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51.
This article proposes an approach for real-time monitoring of risks in executable business process models. The approach considers risks in all phases of the business process management lifecycle, from process design, where risks are defined on top of process models, through to process diagnosis, where risks are detected during process execution. The approach has been realized via a distributed, sensor-based architecture. At design-time, sensors are defined to specify risk conditions which when fulfilled, are a likely indicator of negative process states (faults) to eventuate. Both historical and current process execution data can be used to compose such conditions. At run-time, each sensor independently notifies a sensor manager when a risk is detected. In turn, the sensor manager interacts with the monitoring component of a business process management system to prompt the results to process administrators who may take remedial actions. The proposed architecture has been implemented on top of the YAWL system, and evaluated through performance measurements and usability tests with students. The results show that risk conditions can be computed efficiently and that the approach is perceived as useful by the participants in the tests.  相似文献   
52.
Effective identification of polynomial input–output models for applications requiring long-range prediction or simulation performance relies on both careful model selection and accurate parameter estimation. The simulation error minimisation (SEM) approach has been shown to provide significant advantages in the model selection phase by ruling out candidate models with good short-term prediction capabilities but unsuitable long-term dynamics. However, SEM-based parameter estimation has been generally avoided due to excessive computational effort. This article extends to the nonlinear case a computationally efficient approach for this task, that was previously developed for linear models, based on the iterative estimation of predictors with increasing prediction horizon. Conditions for the applicability of the approach to various model classes are also discussed. Finally, some examples are provided to show the effectiveness and computational convenience of the proposed algorithm for polynomial input–output identification, as well as the improvements achievable by enforcing SEM parameter estimation. A benchmark for nonlinear identification is also analysed, with encouraging results.  相似文献   
53.
This article proposes to test the feasibility of long-term surface deformation monitoring based on synthetic aperture radar (SAR) interferometry on carbon dioxide (CO2) storage sites with land cover representative of potential European injection sites (agricultural or forests with minimum built-up land cover). Because no operational injection site is currently active in Europe, a SAR data set (based on EnviSAT–ASAR spaceborne data) is simulated by combining SAR scenes acquired over a potential future European injection site with deformation measurements from SAR analysis carried out on the In-Salah (Algeria) CO2 injection demonstrator site. The study shows that under such conditions, both persistent scatterer interferometry (PSI) and diffuse scatterer (DS) interferometry appear insufficient to provide a sufficiently dense measurement network to characterize surface deformation correctly. Alternative solutions, to be investigated in further studies, include the use of data archives with shorter acquisition time spans (e.g. Sentinel-1 data when available) or installation of corner reflectors. The cost of the latter mixed space/ground solution must be evaluated with respect to conventional ground-based measurement methods in the proposed context.  相似文献   
54.
55.
Thermoelectric TiNiSn-based half Heusler compound reveals high Seebeck coefficient and electrical conductivity, leading to high power factor. As a consequence of the solidification path, TiNiSn single phase cannot be obtained directly from the liquid phase. Thus, a long annealing step is needed to homogenize the alloy. In this work, we present a new processing route for half Heusler compound formation, combining arc melting of pure elements, rapid solidification of the molten alloy and sintering. Rapid solidification of the molten alloy allows to obtain almost single TiNiSn phase, limiting the formation of the primary TiNi2Sn phase as a consequence of the deep undercooling of the liquid. The rapidly solidified alloy was ground to powder and sintered by open die pressing. As-sintered samples show a density around 95% of the theoretical value. Thermal cycling of the sintered samples shows evolution of the phases, suggesting that after sintering the sample is not in equilibrium yet. After the second thermal cycle thermoelectric properties become reproducible, indicating the attainment of the equilibrium. In conclusion, the proposed processing route allows to obtain dense TiNiSn in bulk form avoiding the time-consuming annealing step, typically used to homogenize this alloy after solidification.  相似文献   
56.
The health‐promoting properties of the Mediterranean diet have been attributed, at least in part, to the chemical diversity of plant foods. Among phytochemicals, polyphenols represent the paradigm of the relationship between healthy foods and reduced risk of chronic‐degenerative diseases, although, in the past few years, a new element has enriched this scenario. Melatonin, and possibly other indoleamines recently discovered in some relevant Mediterranean foods, may represent a new factor contributing to the elucidation of the protective effects of diets rich in plant products. Therefore, in synergy with polyphenols and other bioactive phytochemicals (e.g. carotenoids and glucosinolates), melatonin may contribute to maximizing the benefits of healthy dietary styles. This brief survey deals with the occurrence of melatonin in the Mediterranean diet, with an emphasis on grape products, and focuses on the biological significance of dietary melatonin, an emerging and exciting topic in the field of nutritional sciences. © 2014 Society of Chemical Industry  相似文献   
57.
Lipopolysaccharides (LPSs) are bacterial surface glycolipids, produced by Gram-negative bacteria. LPS is known to determine acute inflammatory reactions, particularly in the context of sepsis. However, LPS can also trigger chronic inflammation. In this case, the source of LPS is not an external infection, but rather an increase in endogenous production, which is usually sustained by gut microbiota (GM), and LPS contained in food. The first site in which LPS can exert its inflammatory action is the gut: both GM and gut-associated lymphoid tissue (GALT) are influenced by LPS and shift towards an inflammatory pattern. The changes in GM and GALT induced by LPS are quite similar to the ones seen in IBD: GM loses diversity, while GALT T regulatory (Tregs) lymphocytes are reduced in number, with an increase in Th17 and Th1 lymphocytes. Additionally, the innate immune system is triggered, through the activation of toll-like receptor (TLR)-4, while the epithelium is directly damaged, further triggering inflammation. In this review, we will discuss the importance of the crosstalk between LPS, GM, and GALT, and discuss the possible implications.  相似文献   
58.
Metallic glasses exhibit particularly attractive mechanical properties, like high stresses to fracture and large elastic strain (up to 2%), but they show generally low plasticity. Aim of this work is to investigate the glass forming range in the Cu–Y system, in order to form the ductile CuY phase (CsCl structure) upon crystallization. Cu58Y42, Cu50Y50 and Cu33Y67 alloys have been prepared by rapid solidification and copper mould casting, obtaining ribbons and cylindrical shaped ingots, with diameter of 2 mm. Fully amorphous, partially amorphous and fully crystalline samples have been obtained for different compositions and quenching conditions. In some cases, the X-ray diffraction results, analysed using the Rietveld method, showed CuY nanocrystals embedded in an amorphous matrix. The microstructure was studied by transmission electron microscopy (TEM) and the presence of nanocrystals of the ductile phase CuY has been confirmed. Microhardness results showed a softening of the amorphous phase due to the presence of CuY nanocrystals and a hardening due to the Cu2Y phase.  相似文献   
59.
A coupled ground-water∕channel flow distributed model has been developed for continuous simulation in a 123-km2 basin. The aim was to analyze the streamflow generation processes in natural vegetated environments. Finite-difference schemes have been used to solve conservation equations of the 2D saturated subsurface flow and the 1D kinematic surface flow. Because of the high hydraulic conductivity of the surface soil, only the saturation excess mechanism of runoff production has been considered. Parameter sensitivity analysis showed the overriding influence of soil storage capacity and conductivity. A grid discretization >100 m produces a hydraulic conductivity greater than physically meaningful, which considerably increases as the space-grid step increases. Results indicate that the model can satisfactorily simulate the water-flow behavior of the catchment after fitting the three parameters of surface hydraulic conductivity, effective porosity, and evapotranspiration losses. These are done after calculating the conductivity as a function of the height of the water table. The simulation efficiency has varied from 87% in the first 5-year calibration period to 85.8% in the subsequent 5-year validation period.  相似文献   
60.
In this paper a novel CAD methodology for yield enhancement of VLSI CMOS circuits including random device variations is presented. The methodology is based on a preliminary characterization of the technological process by means of specific test chips for accurate mismatch modeling. To this purpose, a very accurate position-dependent parameter mismatch model has been formulated and extracted. Finally a CAD tool implementing this model has been developed. The tool is fully integrated in an environment of existing commercial tools and it has been experimented in the STMicroelectronics Flash Memory CAD Group.As an example of application, a bandgap reference circuit has been considered and the results obtained from simulations have been compared with experimental data. Furthermore, the methodology has been applied to the read path of a complex Flash Memory produced by STMicroelectronics, consisting of about 16,000 MOSFETs. Measurements of electrical performances have confirmed the validity of the methodology, and the accuracy of both the mismatch model and the simulation flow.  相似文献   
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