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61.
This article presents two algorithms for online mode thermal stress determination in machinery components based on Green's Function Technique approach and on the artificial neural network, respectively. A modification of the GFT algorithm is proposed involving the use of the component metal temperature rather than the temperature of the flowing fluid. The algorithms developed were used to calculate stresses in rotors and casings of new generation turbines. A possibility was also shown of using the algorithms to solve the inverse problem, i.e., to control the rate of temperature changes while keeping stresses within an allowable range. 相似文献
62.
Jan Langer Marian Klasztorny Salah El-Sayed El-Bagalaty' 《International journal for numerical methods in engineering》1992,33(5):889-905
The paper presents a family of methods with postintegration, for numerical integration of non-linear dynamic equations of motion of discrete systems. Both explicit and implicit algorithms of these methods are conditionally stable, but can give solutions of accuracy of a few orders higher than the known methods with preintegration, corresponding to them. A general analysis of stability and accuracy of single-step methods is carried out. The postintegration methods have been tested on a single-degree-of-freedom non-linear system. 相似文献
63.
Mariana Pinteala Valeria Harabagiu Cornelia Cotzur Marian N. Holerca Bogdan C. Simionescu 《Polymer Bulletin》1994,32(2):173-178
Summary Carboxyester- and carboxyamido-terminated polydimethylsiloxanes were obtained through the reaction of cyclic anhydrides (succinic, maleic and phthalic anhydride) with hydroxypropyl- and aminoalkyl-terminated polydimethylsiloxanes, respectively. The reactivity of the starting compounds and the influence of the reaction conditions on the characteristics of the final products are discussed.Part 1: Eur. Polym. J., in press 相似文献
64.
Jens Bender Dennis Kügler Marian Margraf Ingo Naumann 《Datenschutz und Datensicherheit - DuD》2010,34(5):295-298
Dieser Artikel beschreibt im Detail die datenschutzfreundliche Ausgestaltung des Sperrmanagements, wie es im neuen deutschen Personalausweis zum Einsatz kommt. 相似文献
65.
Turek Marian 《中国矿业大学学报(英文版)》2011,21(1)
The author presents the results being the effect of the analysis of innovative rate of individual technologies applied in opening up, development and extraction works which was carried out within the project: "scenarios of technological development of hard coal extractive industry". After presentation of opening up, development and extraction technologies that are applied in Polish hard coal industry and their classification with regard to innovation degree the author describes those technologies in a detailed manner. He brings attention to the most effective systems for hard coal deposits' opening up, development and their extraction, including the extraction of the residual coal. The attention is also paid to the safety level of the applied technologies. 相似文献
66.
Peter Kubatka Martin Kello Karol Kajo Marek Samec Alena Liskova Karin Jasek Lenka Koklesova Tomas Kuruc Marian Adamkov Karel Smejkal Emil Svajdlenka Peter Solar Martin Pec Dietrich Büsselberg Vladimira Sadlonova Jan Mojzis 《International journal of molecular sciences》2021,22(1)
Comprehensive scientific data provide evidence that isolated phytochemicals or whole plant foods may beneficially modify carcinogenesis. The aim of this study was to evaluate the oncostatic activities of Rhus coriaria L. (sumac) using animal models (rat and mouse), and cell lines of breast carcinoma. R. coriaria (as a powder) was administered through the diet at two concentrations (low dose: 0.1% (w/w) and high dose: 1 % (w/w)) for the duration of the experiment in a syngeneic 4T1 mouse and chemically-induced rat mammary carcinoma models. After autopsy, histopathological and molecular analyses of tumor samples in rodents were performed. Moreover, in vitro analyses using MCF-7 and MDA-MB-231 cells were conducted. The dominant metabolites present in tested R. coriaria methanolic extract were glycosides of gallic acid (possible gallotannins). In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. In addition, treated tumors showed significant dose-dependent decrease in mitotic activity index by 36.5% and 51% in comparison with the control group. In the chemoprevention study using rats, R. coriaria at a higher dose significantly reduced the tumor incidence by 20% and in lower dose non-significantly reduced tumor frequency by 29% when compared to controls. Evaluations of the mechanism of oncostatic action using valid clinical markers demonstrated several positive alterations in rat tumor cells after the treatment with R. coriaria. In this regard, histopathological analysis of treated tumor specimens showed robust dose-dependent decrease in the ratio of high-/low-grade carcinomas by 66% and 73% compared to controls. In treated rat carcinomas, we found significant caspase-3, Bax, and Bax/Bcl-2 expression increases; on the other side, a significant down-regulation of Bcl-2, Ki67, CD24, ALDH1, and EpCam expressions and MDA levels. When compared to control specimens, evaluation of epigenetic alterations in rat tumor cells in vivo showed significant dose-dependent decrease in lysine methylation status of H3K4m3 and H3K9m3 and dose-dependent increase in lysine acetylation in H4K16ac levels (H4K20m3 was not changed) in treated groups. However, only in lower dose of sumac were significant decreases in the expression of oncogenic miR210 and increase of tumor-suppressive miR145 (miR21, miR22, and miR155 were not changed) observed. Finally, only in lower sumac dose, significant decreases in methylation status of three out of five gene promoters–ATM, PTEN, and TIMP3 (PITX2 and RASSF1 promoters were not changed). In vitro evaluations using methanolic extract of R. coriaria showed significant anticancer efficacy in MCF-7 and MDA-MB-231 cells (using Resazurin, cell cycle, annexin V/PI, caspase-3/7, Bcl-2, PARP, and mitochondrial membrane potential analyses). In conclusion, sumac demonstrated significant oncostatic activities in rodent models of breast carcinoma that were validated by mechanistic studies in vivo and in vitro. 相似文献
67.
Ryszard Zadernowski Marian Naczk Sylwester Czaplicki 《European Journal of Lipid Science and Technology》2009,111(7):698-704
The chemical composition of oil obtained from Pinus sibirica was investigated. The nonpolar lipids were the predominant lipid fraction while the triacylglycerols were the major component of this fraction. α‐ and γ‐tocopherols were the dominant tocopherols in pine oils. Eleven fatty acids (FA) were identified in pine nut oil. The unsaturated FA comprised over 90% of the total FA. Of these, polyunsaturated FA accounted for 66% of the total FA. 18:2 and 18:3 acids were the dominant unsaturated FA, while palmitic and stearic acids were the major saturated FA. Three unusual FA, namely 10,13‐octadecadienoic, gorlic and 11,13‐eicosadienoic acid, were tentatively identified in pine nut oil. 相似文献
68.
69.
Experimental breads were made with 2, 4, 6, 8, 10, and 12% torula yeast flour (TYF). Taste panels found that bread fortified with 8% TYF was acceptable. Eight percent TYF raised protein content from 12.42% for all wheat flour bread to 14.22% for supplemented bread. Amino acid analyses indicated a marked increase in amino acid content especially lysine. The protein efficiency ratio (PER) for rats on all-wheat-flour bread was 1.3 1; replacing 8% of the wheat flour with TYF raised PER of supplemented bread to 2.28. Total carcass nitrogen retained by animals fed a diet containing supplemented bread was higher than that retained by rats whose protein was obtained from unsupplemented bread. 相似文献
70.
Review of book: Heinz Kohut (Au.) Paul Tolpin and Marian Tolpin (Eds.) The Chicago Institute Lectures. Hillsdale, NJ: Analytic Press, 1996, 432 pp. Reviewed by Donna M. Orange. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献