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51.
Intensive research in the area of medical nanotechnology, especially to cope with the bacterial resistance against conventional antibiotics, has shown strong antimicrobial action of metallic and metal-oxide nanomaterials towards a wide variety of bacteria. However, the important remaining problem is that nanomaterials with highest antibacterial activity generally express also a high level of cytotoxicity for mammalian cells. Here we present gallium nanoparticles as a new solution to this problem. We developed a nanocomposite from bioactive hydroxyapatite nanorods (84?wt %) and antibacterial nanospheres of elemental gallium (16?wt %) with mode diameter of 22?±?11?nm. In direct comparison, such nanocomposite with gallium nanoparticles exhibited better antibacterial properties against Pseudomonas aeruginosa and lower in-vitro cytotoxicity for human lung fibroblasts IMR-90 and mouse fibroblasts L929 (efficient antibacterial action and low toxicity from 0.1 to 1?g/L) than the nanocomposite of hydroxyapatite and silver nanoparticles (efficient antibacterial action and low toxicity from 0.2 to 0.25?g/L). This is the first report of a biomaterial composite with gallium nanoparticles. The observed strong antibacterial properties and low cytotoxicity make the investigated material promising for the prevention of implantation–induced infections that are frequently caused by P. aeruginosa.  相似文献   
52.
This paper presents a Computational Intelligence scheme to deal with subjective human inspection tasks in the industry that are subjective measurements. The scheme is used to solve two cosmetic subjective measurements tasks, classification of cosmetic defects and detection of non-uniform color regions in a translucent film. The first problem is solved with two approaches supervised and unsupervised Artificial Neural Networks. Both techniques yield the same performance, 92.35% of correct classification. Considering that a human inspector has a performance between 85% and 90%, the performance achieved is acceptable. The second problem is faced with a hybrid system based on fuzzy clustering and a Self-Organizing Map. The hybrid approach involves management of uncertainty through fuzzy theory and unsupervised training supported by the SOM. The proposed system is able to find non-uniform color regions with better resolution than a human inspector. The system also showed to be more sensitive than a simple fuzzy clustering approach.  相似文献   
53.
ContextModel-Driven Development (MDD) is an alternative approach for information systems development. The basic underlying concept of this approach is the definition of abstract models that can be transformed to obtain models near implementation. One fairly widespread proposal in this sphere is that of Model Driven Architecture (MDA). Business process models are abstract models which additionally contain key information about the tasks that are being carried out to achieve the company’s goals, and two notations currently exist for modelling business processes: the Unified Modelling Language (UML), through activity diagrams, and the Business Process Modelling Notation (BPMN).ObjectiveOur research is particularly focused on security requirements, in such a way that security is modelled along with the other aspects that are included in a business process. To this end, in earlier works we have defined a metamodel called secure business process (SBP), which may assist in the process of developing software as a source of highly valuable requirements (including very abstract security requirements), which are transformed into models with a lower abstraction level, such as analysis class diagrams and use case diagrams through the approach presented in this paper.MethodWe have defined all the transformation rules necessary to obtain analysis class diagrams and use case diagrams from SBP, and refined them through the characteristic iterative process of the action-research method.ResultsWe have obtained a set of rules and a checklist that make it possible to automatically obtain a set of UML analysis classes and use cases, starting from SBP models. Our approach has additionally been applied in a real environment in the area of the payment of electrical energy consumption.ConclusionsThe application of our proposal shows that our semi-automatic process can be used to obtain a set of useful artifacts for software development processes.  相似文献   
54.
Vehicular sensing where vehicles on the road continuously gather, process, and share location-relevant sensor data (e.g., road condition, traffic flow) is emerging as a new network paradigm for sensor information sharing in urban environments. Recently, smartphones have also received a lot of attention for their potential as portable vehicular urban sensing platforms, as they are equipped with a variety of environment and motion sensors (e.g., audio/video, accelerometer, and GPS) and multiple wireless interfaces (e.g., WiFi, Bluetooth and 2/3G). The ability to take a smartphone on board a vehicle and to complement the sensors of the latter with advanced smartphone capabilities is of immense interest to the industry. In this paper we survey recent vehicular sensor network developments and identify new trends. In particular we review the way sensor information is collected, stored and harvested using inter-vehicular communications (e.g., mobility-assist mobility-assisted dissemination and geographic storage), as well using the infrastructure (e.g., centralized and distributed storage in the wired Internet). The comparative performance of the various sensing schemes is important to us. Thus, we review key results by carefully examining and explaining the evaluation methodology, in the process gaining insight into vehicular sensor network design. Our comparative study confirms that system performance is impacted by a variety of factors such as wireless access methods, mobility, user location, and popularity of the information.  相似文献   
55.
Currently, the design of aesthetic products is a process that requires a set of activities where digital models and physical mockups play a key role. Typically, these are modified (and built) several times before reaching the desired design, increasing the development time and, consequently, the final product cost. In this paper, we present an innovative design environment for computer-aided design (CAD) surface analysis. Our system relies on a direct visuo-haptic display system, which enables users to visualize models using a stereoscopic view, and allows the evaluation of sectional curves using touch. Profile curves are rendered using an haptic device that deforms a plastic strip, thanks to a set of actuators, to reproduce the curvature of the shape co-located with the virtual model. By touching the strip, users are able to evaluate shape characteristics, such as curvature or discontinuities (rendered using sound), and to assess the surface quality. We believe that future computer-aided systems (CAS)/CAD systems based on our approach will contribute in improving the design process at industrial level. Moreover, these will allow companies to reduce the product development time by reducing the number of physical mockups necessary for the product design evaluation and by increasing the quality of the final product, allowing a wider exploration and comparative evaluation of alternatives in the given time.  相似文献   
56.
This paper describes the architecture and implementation of a distributed autonomous gardening system with applications in urban/indoor precision agriculture. The garden is a mesh network of robots and plants. The gardening robots are mobile manipulators with an eye-in-hand camera. They are capable of locating plants in the garden, watering them, and locating and grasping fruit. The plants are potted cherry tomatoes enhanced with sensors and computation to monitor their well-being (e.g. soil humidity, state of fruits) and with networking to communicate servicing requests to the robots. By embedding sensing, computation, and communication into the pots, task allocation in the system is de-centrally coordinated, which makes the system scalable and robust against the failure of a centralized agent. We describe the architecture of this system and present experimental results for navigation, object recognition, and manipulation as well as challenges that lie ahead toward autonomous precision agriculture with multi-robot teams.  相似文献   
57.
Collaboration in transportation between two or more agents is becoming an important approach to find efficient solutions or plans. Efficiency can be measured in, for example, lower cost or more flexibility. An important aspect of the collaboration is to decide on how to share the benefits—for example, cost, profit, or resources. There are many sharing mechanisms or cost allocations proposed in the literature. Some are based on simple proportional rules and others are based on theoretical concepts found in game theory. We provide a survey on cost allocation methods found in the literature on collaborative transportation, including problems on planning, vehicle routing, traveling salesman, distribution, and inventory. A total of 55 scientific articles compose the main part of the survey, most of them published between 2010 and 2015. We identify more than 40 cost allocation methods used in this stream of literature. We describe the theoretical basis for the main methods as well as the cases where they are used. We also report savings from the collaborations when they are based on industrial data. Some directions for future research are discussed.  相似文献   
58.
A smart Information and Communication Technology (ICT) enables a synchronized interplay of different key factors, aligning infrastructures, consumers, and governmental policy-making needs. In the harbor’s logistics context, smart ICT has been driving a multi-year wave of growth. Although there is a standalone value in the technological innovation of a task, the impact of a new smart technology is unknown without quantitative analysis methods on the end-to-end process. In this paper, we first present a review of the smart ICT for marine container terminals, and then we propose to evaluate the impact of such smart ICT via business process model and notation (BPMN) modeling and simulation. The proposed approach is discussed in a real-world modeling and simulation analysis, made on a pilot terminal of the Port of Leghorn (Italy).  相似文献   
59.
60.
Organizations are increasingly concerned about business process model improvement in their efforts to guarantee improved operational efficiency. Quality assurance of business process models should be addressed in the most objective manner, e.g., through the application of measures, but the assessment of measurement results is not a straightforward task and it requires the identification of relevant indicators and threshold values, which are able to distinguish different levels of process model quality. Furthermore, indicators must support the improvements of the models by using suitable guidelines. In this paper, we present a case study to evaluate the BPMIMA framework for BP model improvement. This framework is composed of empirically validated measures related to quality characteristics of the models, a set of indicators with validated thresholds associated with modeling guidelines and a prototype supporting tool. The obtained data suggest that the redesign by applying guidelines driven by the indicator results was successful, as the understandability and modifiability of the models were improved. In addition, the changes in the models according to guidelines were perceived as acceptable by the practitioners who participated in the case study.  相似文献   
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