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31.
32.
González-Coloma A Reina M Medinaveitia A Guadaño A Santana O Martínez-Díaz R Ruiz-Mesía L Alva A Grandez M Díaz R Gavín JA De la Fuente G 《Journal of chemical ecology》2004,30(7):1393-1408
We have tested the insect antifeedant and toxic activity of 43 norditerpenoid alkaloids on Spodoptera littoralis and Leptinotarsa decemlineata including eserine (physostigmine), anabasine, and atropine. Antifeedant effects of the test compounds were structure- and species-dependent. The most active antifeedants to L. decemlineata were 1,14-diacetylcardiopetaline (9) and 18-hydroxy- 14-O-methylgadesine (33), followed by 8-O-methylconsolarine (12), 14-O-acetyldelectinine (27), karakoline (7), cardiopetaline (8), 18-O-demethylpubescenine (13), 14-O-acetyldeltatsine (18), takaosamine (21), ajadine (24), and 8-O-methylcolumbianine (6) (EC50 < 1 microg/cm2). This insect showed a moderate response to atropine. S. littoralis had the strongest antifeedant response to 24, 18, 14-O-acetyldelcosine (19), and delphatine (29) (EC50 < 3 microg/cm2). None of the model substances affected the feeding behavior of this insect. The most toxic compound to L. decemlineata was aconitine (1), followed by cardiopetalidine (10) (% mortality > 60), 14-deacetylpubescenine (14), 18-O-benzoyl-18-O-demethyl-14-O-deacetylpubescenine (17), 14-O-acetyldelcosine (19), 14-deacetylajadine (25) and methyllycaconitine (30) (% mortality > 45). Orally injected S. littoralis larvae were negatively affected by 1, cardiopetaline (8), 10, 1,14-O-acetylcardiopetalidina (11), 12, 14, 1,18-O-diacetyl-19-oxo-gigactonine (41), olivimine (43), and eserine in varying degrees. Their antifeedant or insecticidal potencies did not parallel their reported nAChR binding activity, but did correlate with the agonist/antagonist insecticidal/antifeedant model proposed for nicotininc insecticides. A few compounds [14, tuguaconitine (38), 14-demethyldelboxine (40), 19, dehydrodelsoline (36), 18-O-demethylpubescenine (13), 41, 9, and delcosine (23)] had selective cytotoxic effects to ward insect-derived Sf9 cells. None were cytotoxic to mammalian CHO cells and none increased Trypanosoma cruzi mortality. The selective cytotoxic effects of some structures indicate that they can act on biological targets other than neuroreceptors. 相似文献
33.
Antonio Muñoz San Roque Carlos Maté Javier Arroyo Ángel Sarabia 《Neural Processing Letters》2007,25(2):157-169
Interval-valued data offer a valuable way of representing the available information in complex problems where uncertainty,
inaccuracy or variability must be taken into account. In addition, the combination of Interval Analysis with soft-computing
methods, such as neural networks, have shown their potential to satisfy the requirements of the decision support systems when
tackling complex situations. This paper proposes and analyzes a new model of Multilayer Perceptron based on interval arithmetic
that facilitates handling input and output interval data, but where weights and biases are single-valued and not interval-valued.
Two applications are considered. The first one shows an interval-valued function approximation model and the second one evaluates
the prediction intervals of crisp models fed with interval-valued input data. The approximation capabilities of the proposed
model are illustrated by means of its application to the forecasting of daily electricity price intervals. Finally, further
research issues are discussed.
Research funded by Universidad Pontificia Comillas. 相似文献
34.
Isabel Matía Fernando González-Camacho Roberto Marco John Z. Kiss Gilbert Gasset Jack van Loon Francisco Javier Medina 《Microgravity science and technology》2007,19(5-6):128-132
In an experiment conducted in the “Cervantes” Spanish Soyuz Mission, a 10-day flight to the International Space Station, Arabidopsis seeds were germinated, seedlings grew for 4 days at 22ºC, and they were fixed in flight with paraformaldehyde. A ground 1 g control experiment was replicated, and an additional experiment in simulated microgravity, using a Random Positioning Machine, was performed in the same conditions. Structural, morphometric and immunocytochemical data were compared. Glutaraldehyde-fixed seedlings similarly grown in the Space Shuttle (STS-84 Mission) were also used for ultrastructural and morphometric studies. Seedlings grown for 4 days in real or simulated weightlessness showed a longer size than the ground 1 g control. Root meristematic cells showed an enhanced proliferating rate, but ribosome biogenesis was reduced, as inferred from the nucleolar size and from the levels of the nucleolar protein nucleolin. This could be the consequence of the acceleration of the cell cycle, with shortening of its phases. Weightlessness induces stress in the plant, influencing cellular processes decisive for development and morphogenesis. This stress may endanger the plant and would require the action of compensating specialized defence mechanisms. 相似文献
35.
Jérémie Chalopin Shantanu Das Yann Disser Matúš Mihalák Peter Widmayer 《Algorithmica》2013,65(1):43-59
We consider the problem of mapping an initially unknown polygon of size n with a simple robot that moves inside the polygon along straight lines between the vertices. The robot sees distant vertices in counter-clockwise order and is able to recognize the vertex among them which it came from in its last move, i.e. the robot can look back. Other than that the robot has no means of distinguishing distant vertices. We assume that an upper bound on n is known to the robot beforehand and show that it can always uniquely reconstruct the visibility graph of the polygon. Additionally, we show that multiple identical and deterministic robots can always solve the weak rendezvous problem in which the robots need to position themselves such that all of them are mutually visible to each other. Our results are tight in the sense that the strong rendezvous problem, where robots need to gather at a vertex, cannot be solved in general, and, without knowing a bound beforehand, not even n can be determined. In terms of mobile agents exploring a graph, our result implies that they can reconstruct any graph that is the visibility graph of a simple polygon. This is in contrast to the known result that the reconstruction of arbitrary graphs is impossible in general, even if n is known. 相似文献
36.
Abdul Nasir Khan M. L. Mat Kiah Sajjad A. Madani Atta ur Rehman Khan Mazhar Ali 《The Journal of supercomputing》2013,66(3):1687-1706
To improve the resource limitation of mobile devices, mobile users may utilize cloud-computational and storage services. Although the utilization of the cloud services improves the processing and storage capacity of mobile devices, the migration of confidential information on untrusted cloud raises security and privacy issues. Considering the security of mobile-cloud-computing subscribers’ information, a mechanism to authenticate legitimate mobile users in the cloud environment is sought. Usually, the mobile users are authenticated in the cloud environment through digital credential methods, such as password. Once the users’ credential information theft occurs, the adversary can use the hacked information for impersonating the mobile user later on. The alarming situation is that the mobile user is unaware about adversary’s malicious activities. In this paper, a light-weight security scheme is proposed for mobile user in cloud environment to protect the mobile user’s identity with dynamic credentials. The proposed scheme offloads the frequently occurring dynamic credential generation operations on a trusted entity to keep minimum processing burden on the mobile device. To enhance the security and reliability of the scheme, the credential information is updated frequently on the basis of mobile-cloud packets exchange. Furthermore, the proposed scheme is compared with the existing scheme on the basis of performance metrics i.e. turnaround time and energy consumption. The experimental results for the proposed scheme showed significant improvement in turnaround time and energy consumption as compared to the existing scheme. 相似文献
37.
This paper explores the definition, applications, and limitations of concepts and concept maps in C++, with a focus on library composition. We also compare and contrast concepts to adaptation mechanisms in other languages.Efficient, non-intrusive adaptation mechanisms are essential when adapting data structures to a library’s API. Development with reusable components is a widely practiced method of building software. Components vary in form, ranging from source code to non-modifiable binary libraries. The Concepts language features, slated to appear in the next version of C++, have been designed with such compositions in mind, promising an improved ability to create generic, non-intrusive, efficient, and identity-preserving adapters.We report on two cases of data structure adaptation between different libraries, and illustrate best practices and idioms. First, we adapt GUI widgets from several libraries, with differing APIs, for use with a generic layout engine. We further develop this example to describe the run-time concept idiom, extending the applicability of concepts to domains where run-time polymorphism is required. Second, we compose an image processing library and a graph algorithm library, by making use of a transparent adaptation layer, enabling the efficient application of graph algorithms to the image processing domain. We use the adaptation layer to realize a few key algorithms, and report little or no performance degradation. 相似文献
38.
Jiří Matějíček František Zahálka Jan Bensch Weiguang Chi Josef Sedláček 《Journal of Thermal Spray Technology》2008,17(2):177-180
Copper and copper-tungsten composite coatings were produced by high-velocity oxy-fuel spraying (HVOF). After initial optimization
of the spraying parameters, coatings of various compositions were made and their structure, composition, mechanical, thermal,
and electrical properties were characterized. The HVOF technique was able to produce rather dense coatings with minimal oxide
content and relatively good mechanical and thermal properties compared to, for example, plasma-sprayed coatings; however,
the achieved tungsten content was quite low. 相似文献
39.
This paper presents a methodology of a design optimization technique that can be useful in assessing the best configuration of a finned‐tube evaporator, using a thermoeconomic approach. The assessment has been carried out on a direct expansion finned‐tube evaporator of a vapor compression cycle for a roof‐top bus air‐conditioning (AC) system at a specified cooling capacity. The methodology has been conducted by studying the effect of some operational and geometrical design parameters for the evaporator on the entire cycle exergy destruction or irreversibility, AC system coefficient of performance (COP), and total annual cost. The heat exchangers for the bus AC system are featured by a very compact frontal area due to the stringent space limitations and structure standard for the system installation. Therefore, the current study also takes in its account the effect of the variation of the design parameters on the evaporator frontal area. The irreversibility due to heat transfer across the stream‐to‐stream temperature difference and due to frictional pressure drops is calculated as a function of the design parameters. A cost function is introduced, defined as the sum of two contributions, the investment expense of the evaporator material and the system compressor, and the operational expense of AC system that is usually driven by an auxiliary engine or coupled with the main bus engine. The optimal trade‐off between investment and operating cost is, therefore, investigated. A numerical example is discussed, in which a comparison between the commercial evaporator design and optimal design configuration has been presented in terms of the system COP and evaporator material cost. The results show that a significant improvement can be obtained for the optimal evaporator design compared with that of the commercial finned‐tube evaporator that is designed based on the conventional values of the design parameters. Copyright © 2007 John Wiley & Sons, Ltd. 相似文献
40.
Lazaros Elias Mavromatidis Pierre Michel Mohamed El Mankibi Mat Santamouris 《Building Simulation》2010,3(4):279-294
This paper reports on a numerical and experimental study of heat transfer phenomena through two different multilayer fibrous
insulations for building applications. The investigated samples were composed of different layers of fibrous materials and
aluminium foils, placed between one or two air gaps in the vertical dimension. An experimental apparatus (a guarded hot box)
has been used to measure heat transfer through the samples, while a finite volume numerical model combined radiation/conduction
heat transfer was developed to predict the temperature distribution and heat transfer in such insulation systems comprised
of the materials separated by multiple reflective foils. The model takes into account the coupling between the solid conduction
of the fibrous system and the gaseous conduction and radiation. The radiation heat transfer through the insulation system
has been modelled via the two flux approximation. The numerical results were compared with the experimental data from the
guarded hot box for model validation, as well as to assess the effectiveness of the reflective foils in changing the resistance
of the insulations. The comparative verification of the model showed that the numerical results were consistent with the experimental
data through the environmental conditions under examination. 相似文献