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The measurement of broadband ultrasonic attenuation (BUA) in cancellous bone at the calcaneus was first described in 1984. The assessment of osteoporosis by BUA has recently been recognized by Universities UK, within its EurekaUK book, as being one of the "100 discoveries and developments in UK Universities that have changed the world" over the past 50 years, covering the whole academic spectrum from the arts and humanities to science and technology. Indeed, BUA technique has been clinically validated and is utilized worldwide, with at least seven commercial systems providing calcaneal BUA measurement. However, a fundamental understanding of the dependence of BUA upon the material and structural properties of cancellous bone is still lacking. This review aims to provide a science- and technology-orientated perspective on the application of BUA to the medical disease of osteoporosis.  相似文献   
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In this paper we present a tabu search heuristic which can be used for scheduling the production at an oil refinery. The scheduling problem is to decide which production modes to use at the different processing units at each point in time. The problem is a type of lot-sizing problem where costs of changeovers, inventories and production are considered. In the suggested tabu search heuristic we explore the use of variable neighbourhood, dynamic penalty and different tabu lists. Computational results are presented for different versions of the heuristic and the results are compared to the best-known lower bound for a set of scheduling scenarios.  相似文献   
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Myosin was isolated from bovine m. semimembranosus and gels were formed by heat treatment at different pH values and ionic strengths. The gels were subjected to rigidity measurements and their microstructure was studied by scanning electron microscopy. This article provides evidence that myosin can form two completely different gel structures in the pH range 5.5–6.0, depending on ionic strength. Fine stranded gel structures were formed at low ionic strength (0.25M KCl), whereas coarsely aggregated gel structures were formed at high ionic strength (0.6M KCl). The fine stranded structure had a higher rigidity than the coarsely aggregated structure. It was found that all fine strand myosin gels were formed from turbid solutions and the aggregate gels from clear solutions. When the pH was lowered to 4 in 0.6M KCl a strand-type gel structure formed spontaneously on dialysis, even without heat treatment. This structure did not change in character on heating. It was concluded that the conditions required for the formation of strand-type myosin gels were already present before the heat treatment and that the strands were made up of myosin filaments at certain pH and ionic strength combinations, which produced a turbid solution. The strand-type structures were considered specific with regard to myosin interactions which was not the case for the aggregated structures. Variation of the heating temperature in the range 55 to 65°C had no major effect on the type of structure formed.  相似文献   
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The direction of another person's gaze is difficult to ignore when presented at the center of attention. In 6 experiments, perception of unattended gaze was investigated. Participants made directional (left-right) judgments to gazing-face or pointing-hand targets, which were accompanied by a distractor face or hand. Processing of the distractor was assessed via congruency effects on target response times. Congruency effects were found from the direction of distractor hands but not from the direction of distractor gazes (Experiment 1). This pattern persisted even when distractor sizes were increased to compensate for their peripheral presentation (Experiments 2 and 5). In contrast, congruency effects were exerted by profile heads (Experiments 3 and 4). In Experiment 6, isolated eye region distractors produced no congruency effects, even when they were presented near the target. These results suggest that, unlike other facial information, gaze direction cannot be perceived outside the focus of attention. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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Polychrome alabaster carvings, representing religious scenes, constitute England's major contribution to European mediaeval sculpture. During the period between 1350 and 1550, large number of alabaster carvings were produced in the Midlands. Despite their massive destruction during the English Reformation (ca.1534), more than 2500 of them still survive, either legally exported or sold clandestinely to the Continent. With more than 100 panels still existing, the Bordeaux region holds one of the largest concentrations of these reliefs. Most of them have unfortunately lost their medieval polychromy, but 20 can still provide valuable information. They are currently studied in our multidisciplinary research program “ALBATRES” (Polychromie, pigments, perception: les albâtres anglais de la fin du Moyen Âge conservés sur le territoire aquitain. Labex LaScArBx project [2018-2020]). Focused on the panels' polychromy, the project links art history, archaeometry, optical and 3D engineering, and experimental archeology. The first aim is to obtain complete information on the materials and techniques used by medieval painters. The second consists in studying the functions of polychromy and its perception, by determining and interpreting the selection criteria and aesthetic uses of colors and gilding. The polychrome remains of the Aquitaine corpus are studied by means of visual examination, macrophotographic documentation, and noninvasive portable spectroscopic analyses (reflectance spectroscopy by fiber optics in visible and infrared ranges, fluorimetry, etc.). They reveal, among others, the presence of cinnabar, red lead, red ochre, copper green pigments, yellow ochre, gold, lead white, and others. The results allow the production of model samples to help understand the medieval color organization before proposing the coloring of a real copy of one of the studied panels (Virgin's Assumption, Musée d'Aquitaine, Bordeaux). The shape and the appearance of the color rendering could be improved thanks to a special device built at the IOGS to develop a shader that approximates as closely as possible the appearance of the panels. Finally, all information will be integrated on 3D model panels for better appreciation of the carvings and the artistic taste of medieval spectators.  相似文献   
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Carbon dioxide (CO2) and methane (CH4) diffusive emissions were measured during two field surveys in Queensland and Tasmania, Australia, using the floating chamber method. Bubbling and degassing emissions in 2010 were estimated in Koombooloomba Dam reservoir using only inverted funnels and gas concentrations, respectively. A total of 14 reservoirs and 16 rivers and lakes were sampled from 2006 to 2010. Spatial variation was substantial within each water body, as well as between them. The main drivers of diffusive emission variation were physiographic region and climate, with a clear demarcation being observed between diffusive emissions from tropical Queensland and temperate Tasmania, and between the humid West Coast Range (Tasmania) and dry Central Plateau (Tasmania). Higher CO2 and CH4 diffusive emissions were observed during the dry season, when long water residence times would promote organic matter degradation. Estimated total gross emissions, including diffusive, bubbling and degassing emissions, for Koombooloomba Dam reservoir were about 1.5 × 106 t CO2eq km2 per year, or 24 × 106 t CO2eq per year. This corresponds to a plant emission factor of 3.18 kg CO2eq MWh?1. Using an estimate of terrestrial emissions derived from literature data for the Tully River catchment area, rough estimated net emissions from the catchment area are about 44 kt CO2eq per year, or 5.83 kg CO2eq MWh?1, which is in the lower range of the studied reservoirs.  相似文献   
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A solution for interaction using finger tracking in a cubic immersive virtual reality system (or immersive cube) is presented. Rather than using a traditional wand device, users can manipulate objects with fingers of both hands in a close-to-natural manner for moderately complex, general purpose tasks. Our solution couples finger tracking with a real-time physics engine, combined with a heuristic approach for hand manipulation, which is robust to tracker noise and simulation instabilities. A first study has been performed to evaluate our interface, with tasks involving complex manipulations, such as balancing objects while walking in the cube. The user’s finger-tracked manipulation was compared to manipulation with a 6 degree-of-freedom wand (or flystick), as well as with carrying out the same task in the real world. Users were also asked to perform a free task, allowing us to observe their perceived level of presence in the scene. Our results show that our approach provides a feasible interface for immersive cube environments and is perceived by users as being closer to the real experience compared to the wand. However, the wand outperforms direct manipulation in terms of speed and precision. We conclude with a discussion of the results and implications for further research.  相似文献   
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