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91.
92.
Remanufacturing facilities usually face a trade-off between limited information about remanufacturing yields and potentially long supplier lead times. To improve production performance, these firms may attempt to acquire more timely and accurate information about remanufacturing yields or alternatively, to reduce the lead times of purchased parts. We develop four decision-making models to evaluate the impact of yield information and supplier lead time on manufacturing costs. We identify the operating conditions under which these capabilities are valuable, along with their relative impact on facility performance. Each model is formulated as an infinite horizon, stochastic dynamic program (Markov decision process). Our results indicate that the yield information is generally quite valuable, while investments in supplier responsiveness provide trivial returns to products with few parts. However, as product complexity increases with large number of target parts, the value of short lead times increases. 相似文献
93.
Michael J Doughty 《Contact lens & anterior eye》2003,26(3):117-129
PURPOSE: The present studies were designed to assess whether measurement of corneal stroma swelling in the laboratory, especially in non-physiological solutions, was associated with a measurable effect on the keratocytes. METHODS: Complete corneal stroma preparations were made from quality- and age-selected recent post-mortem cattle eyes. These were either assessed immediately or incubated in three different solutions, namely a balanced salts solution with glucose (BSSG), isotonic phosphate buffered saline (PBS) or pure water. Incubations were carried out at 37 degrees C for 9h, and repeated measures of wet mass made so that the rates and extent of swelling could be determined. After incubation, an aqueous extract was made of the stroma for measurements of the levels the enzymes lactate dehydrogenase (LDH), aldehyde dehydrogenase (ALDH) and N-acetyl-beta-glucosaminidase. RESULTS: The initial rates of swelling were lowest in BSSG, marginally faster in PBS and much faster in water. The secondary rates of swelling showed the same sequence being 10.0%/h in BSSG, 14.8%/h in PBS and 34.2%/h in water. Compared to non-incubated preparations, reductions in all three enzyme activities occurred. For LDH, these were 15% with BSSG, 40% in PBS and 80% with water. Similar results were seen with ALDH activity when comparing the three incubation solutions, while incubation in BSSG also resulted in a substantial (40%) reduction in N-acetyl-glucosaminidase activity. CONCLUSIONS: When immersed in an isotonic BSSG with added glucose at 37 degrees C, the swelling of a complete bovine corneal stroma is much less than smaller pieces of stroma, and also slightly less than if isotonic PBS was used. With the use of BSSG, little or no change in cytoplasmic enzyme activities occurred, but measurable decreases were noted with PBS and very substantial decreases when water was used, indicating a toxic effect on the keratocytes. The observation that substantial decreases in a lysosomal enzyme activity could occur even with the use of BSSG indicate substantial stress is imposed on the stroma during these types of experiments. Notwithstanding, the data collectively indicate that the keratocyte cells within the collagen matrix of the stroma can be substantially damaged and this needs to be taken into account in future experiments on the true physiology of the corneal stroma. 相似文献
94.
This paper investigates the catalytic ignition of the H2/O2/CO2 mixture on platinum in a stagnation flow at atmospheric pressure experimentally and numerically. We measure the ignition temperatures of the gas mixtures flowing towards resistively heated platinum with various composition ratios and various diluent gases of N2, Ar and CO2. Compared with N2 or Ar, the CO2 dilution shows higher ignition temperature by about 50 K, even at the same composition ratio. The ignition temperature increase is proportional to the dilution ratio. Through the numerical simulation, it is illustrated that higher ignition temperature is caused by the adsorption of CO2 and following dissociation on platinum surface, which was to date considered negligible in catalytic combustion. 相似文献
95.
An adaptive p-persistent MAC scheme for multimedia WLAN 总被引:1,自引:0,他引:1
Chih-Ming Yen Chung-Ju Chang Yih-Shen Chen 《Communications Letters, IEEE》2006,10(11):737-739
The letter proposes an adaptive p-persistent-based (APP) medium access control (MAC) scheme for the IEEE 802.11e distributed WLAN supporting multimedia services. The APP MAC scheme adaptively gives differentiated permission probabilities to transmission stations which are in different access category and with various waiting delay. Simulation results show that the APP MAC scheme can improve the performance of multimedia WLAN, such as small voice packet dropping probability, low delay variation, and high system throughput, compared to conventional MAC algorithms 相似文献
96.
Separation tests using hollow-fibre modules were performed for the difficult selective extraction of trivalent actinides over fission lanthanides from acidic media. This article shows that with 2,6-di(5,6-dipropyl-1,2,4-triazin-3-yl)pyridine as the extractant, up to 94% americium could be extracted from 1.0 kmol/m3 HNO3, with minimal lanthanide co-extraction. Using a synergistic mixture of bis(chlorophenyl)dithiophosphinic acid and tri-n-octyl phosphine oxide, tests were performed on extraction, lanthanide scrubbing and stripping. In the extraction test, up to 99.99% americium could be extracted from 0.5 kmol/m3 HNO3, with approximately one third of the lanthanides being co-extracted. Mass transfer calculations using a consistent set of input data showed good agreement with the experiments. 相似文献
97.
Ming-Dou Ker Chyh-Yih Chang Yi-Shu Chang 《Components and Packaging Technologies, IEEE Transactions on》2004,27(3):445-451
This paper reports a real case of electrostatic discharge (ESD) improvement on a complementary metal oxide semiconductor integrated circuit (IC) product with multiple separated power pins. After ESD stresses, the internal damage have been found to locate at the interface circuit connecting between different circuit blocks with different power supplies. Some ESD designs have been implemented to rescue this IC product to meet the required ESD specification. By adding only an extra ESD clamp N-channel metal oxide semiconductor with a channel width of 10 /spl mu/m between the interface node and the ground line, the human-body-model (HBM) ESD level of this IC product can be improved from the original 0.5 to 3 kV. By connecting the separated vertical sync signal (VSS) power lines through the ESD conduction circuit to a common VSS ESD bus realized by the seal ring, the HBM ESD level of the enhanced version IC product with 12 separated power supplies pairs can be significantly improved from original 1 kV up to > 5 kV, without the noise coupling issue. 相似文献
98.
Ching-Wen Tang Chi-Yang Chang 《Electronics letters》2002,38(15):801-803
A novel chip-type ceramic balun designed in the 2.4 GHz ISM band frequency is presented. A buried capacitor is included in the balun, so that the length of the coupled transmission lines can be reduced and can be designed very easily. A meander or spiral broadside coupled-line is adopted to realise the proposed LTCC multi-layer balun. The measured performances of phase and amplitude balance for this LTCC-MLC balun show a good match with computer simulation 相似文献
99.
100.
Amplification or overexpression of HER-2/neu in human lung cancer has been correlated with poor prognosis and chemoresistance. We have previously reported that the adenovirus type 5 early region 1A (E1A) gene product can suppress HER-2/neu-mediated transformation phenotypes through inhibition of HER-2/neu expression. To find an efficient way to treat HER-2/neu-overexpressing lung cancer with E1A, a replication-deficient adenovirus containing the E1A gene, Ad.E1A(+), was used to transduce E1A into HER-2/neu-overexpressing and low expressing human lung cancer cell lines. Tumour cell growth in vitro and colony formation in soft agarose were greatly inhibited by Ad.E1A(+) transduction in HER-2/neu-overexpressing lung cancer cell lines. In HER-2/neu low expressing cell lines, E1A could not inhibit cell growth in vitro but could reduce the colony formation ability in soft agarose, indicating different effects of E1A in these two types of cancer cells. To test the therapeutic efficacy of E1A to lung cancer by systemic delivery in vivo, tumor-bearing mice were established by intratracheal injection of lung cancer cells and treated by i.v. tail injections of Ad.E1A(+). As a result, Ad.E1A(+) suppressed HER-2/neu overexpression and inhibited intratracheal lung cancer growth. However, no significant tumor suppression effect of Ad.E1A(+) was observed in mice bearing HER-2/neu low expressing cell line when the same therapeutic procedure was followed. Thus, we conclude that systemic delivery of Ad.E1A(+) can efficiently achieve therapeutic effect in HER-2/neu-overexpressing lung cancer in vivo. 相似文献