Novel design approach for the creation of 3D geometrical model of personalized bone scaffold

Bone scaffolds provide a structural support for tissue development. Existing bone scaffolds are mainly characterized by complex porous designs whose shortcomings are a low level of permeability for growing tissue, and a difficult design customization. Scaffolds with nucleuses (rods or lattices) as basic elements should improve bone regeneration and enable higher design flexibility. In this paper, we present two new methods for building 3D geometrical models of personalized scaffolds, which are based on method of anatomical features. Methods are demonstrated in the case of scaffold for the mandible bone. This approach greatly reduces the designer effort and time, while enabling easy personalization of scaffolds’ shape and geometry.     

Linear models‐based LPV modelling and control for wind turbines

The non‐linear behaviour of wind turbines demands control strategies that guarantee the robustness of the closed‐loop system. Linear parameter‐varying (LPV) controllers adapt their dynamics to the system operating points, and the robustness of the closed loop is guaranteed in the controller design process. An LPV collective pitch controller has been developed within this work to regulate the generator speed in the above rated power production control zone. The performance of this LPV controller has been compared with two baseline control strategies previously designed, on the basis of classical gain scheduling methods and linear time‐invariant robust H_∞ controllers. The synthesis of the LPV controller is based on the solution of a linear matrix inequalities system, proposed in a mixed‐sensitivity control scenario where not only weight functions are used but also an LPV model of the wind turbine is necessary. As a contribution, the LPV model used is derived from a family of linear models extracted from the linearization process of the wind turbine non‐linear model. The offshore wind turbine of 5 MW defined in the Upwind European project is the used reference non‐linear model, and it has been modelled using the GH Bladed 4.0 software package. The designed LPV controller has been validated in GH Bladed, and an exhaustive analysis has been carried out to calculate fatigue load reductions on wind turbine components, as well as to analyse the load mitigation in some extreme cases. Copyright © 2014 John Wiley & Sons, Ltd.     

Epoxidized perfluoropolyethers: A route to hydrophobic,negative‐tone photoresists

The synthesis, formulation, and wafer level processing conditions of a heavily fluorinated hydrophobic photoresist was demonstrated. The synthesis is based on terminal epoxy modification of commercially available perfluoropolyethers. Structural characterization shows that terminal epoxide can open during the synthetic process, but in a simple formulation has a negligible effect on photoresolution of the photoresist. Formulation into a traditional photoresist requires careful selection of appropriate cosolvents to ensure solubility of the hydrophobic epoxy and hydrophilic photoacid generator while attaining adequate coating quality. Formulation processing conditions are presented and the chemical resistance of the resist through aggressive processing steps is demonstrated. Wafer level patterning using traditional photolithographic tools illustrates the applicability of the formulation and process conditions for traditional resist or microfluidic applications. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011     

Analysis of the strain and hardness in self-cured and light-cured self-adhesive resin based cement

The study showed an application of the 3?D Digital Image Correlation Method (3?D-DIC) for detection of von Mises strain in samples of the self-etch, self-adhesive resin based cement (RBC). The aim was to determine and compare strain in the self-cured and light-cured Maxcem Elite, furthermore to investigate the hardness of these two cement-types. The experiment was carried out using two groups of Maxcem Elite (Kerr, Orange, CA, USA) samples; each tested group includes five (ø5?×?2?mm sized) samples, for both self-curing and light-curing mode. All samples were prepared by filling teflon ring-type molds. In addition, Vickers micro-hardness was measured for all samples. Maxcem Elite showed similar maximum strain values from 10% to 12% for both groups. Besides the maximum strain value, the 3?D-DIC method also enabled monitoring the change of strain field even after the recommended polymerization time. This method has shown that the polymerization shrinkage continues even after 10?min which disagreed with manufacturer’s suggestion. Group II showed maximum strain values of 12% in the peripheral zone after 10?min, in the last Stage (Stage 60). Statistically significant difference was not found in the overall strain between self- and light-cured Maxcem Elite neither peripherally (p?=?0.118) nor centrally (p?=?0.879). However, statistical significance was found in strain regarding central and peripheral zone in both, self-cured (p?=?0.020) and light-cured (p?=?0.002) Maxcem Elite. The mean von Mises strain values in the periphery of the samples (Section 0) were significantly higher compared to strain values in the center of the samples (for Section 1 and 2). The last stage (Stage 60) of the light-cured Maxcem Elite polymerization showed significantly higher values of von Mises strain compared to initial stage (Stage 0). Higher values of micro-hardness were noticed on the surfaces directly exposed to LED lamp after performing measurements of micro-hardness on light-cured samples.     

Theoretical and Experimental Analysis of Moisture-Dependent Thermal Conductivity of Lightweight Ceramic Bricks

The moisture-dependent thermal conductivity of two types of lightweight ceramic brick body is analyzed using both theoretical and experimental approaches. The basic physical properties are determined at first. Then, an impulse method is applied for the thermal-conductivity measurement. Initially, the material samples are dried, after that, they are exposed to liquid water for specific time intervals, and finally the moisture content is allowed to homogenize within the whole volume. The thermal-conductivity measurement is performed for different moisture contents achieved in this way. In the theoretical part, the homogenization principles are used for the calculation of the moisture-dependent thermal conductivity, utilizing the distribution functions based on the pore-size distribution measurement. Finally, a comparison of the measured and calculated data is done, and the validity of the applied effective media treatment is assessed.     

Effect of reduction parameters on the particle size of tungsten monocarbide obtained from the blue tungsten oxide

Conclusions A study was made, using the methods of particle size analysis and metallographic examination, of the effects of temperature and bed thickness in the reduction of the blue tungsten oxide upon some properties of tungsten and tungsten monocarbide powders and sintered 6 wt.% Co hard alloys produced from the monocarbide powders. Quantitative results were obtained showing the relationship between these reduction parameters on the one hand and the particle size of the resultant powders and the physicomechanical properties of hard alloys on the other. It was established that the particle size grows with rise in reduction temperature and with increase in the thickness of the blue oxide bed.Translated from Poroshkovaya Metallurgiya, No. 11(143), pp. 102–107, November, 1974.     

Prenatal gunshot perforation of the colon

Digitoxin plasma levels were determined in the dog by radioimmunoassy after i.v. infusion of this cardenolide in toxic amounts (388 +/- 13 mug/kg). Plasma values found immediately after the administration of this dose were 588.5 +/- 91 ng/ml and attained very low levels (10 ng/ml) 96 h later. The dominant half-life of digitoxin in the dog was found to be 49.6 +/- 6.5 h, but this value was attained only in the final part of our study. The results found are compared with previous data and controversial aspects are discussed.     

Effect of propranolol and IFN-beta on the induction of MHC class II expression and cytokine production by IFN-gamma IN THP-1 human monocytic cells

Technologies for promoting quality of organizational services to the developmentally disabled have been evolving over the past several decades. Feedback reinforcement and, often, goal-setting, powerful change tools, generally are incorporated within behavioral interventions. Despite their promise, wide-scale application of these strategies often is impeded by natural and informal organizational contingencies. In an attempt to combat such impediments, a structure of interlocking contingencies was designed to train and support managers' provision of effective feedback to their subordinates, peers, and superiors. The system included formal scheduling of feedback, reinforcement and goal setting in a way that attempted to (a) minimize financial costs, time and effort; (b) empower participants by involving them in designing the specifics of the system; and (c) promote momentum by encouraging dense schedules of feedback. Within a period of less than 6 months, supervisors, managers, and professional specialists conducted brief audits and delivered nearly 9,000 written feedback reports to workers serving 129 clients, with the result that staff-client interactions and client engagement levels increased substantially. Future research should replicate these methods under more rigorous experimental conditions and formally assess some of the system's spillover into realms such as gains in clients' skill levels, and staff and public acceptance.     

Comparison of different modes of excitation in X-ray emission spectroscopy in the detection of trace elements in coal and coal ash

Three different modes of sample excitation in X-ray emission spectroscopy were used in trace element analysis of coal and coal ash: proton beam, Mo X-ray tube and radioactive sources ⁵⁷Co and ¹⁰⁹Cd. The results of analysis are presented and methods and their possibilities are compared in order to indicate the most appropriate technique for the particular purpose.