Two-phase, all-magnetic shift registers have been designed and operated using either two pulse drivers or a single pulse driver and a dc source. The theory of operation of a one-core-per-bit register and a two-core-per-bit register is presented. Experimental information is given that demonstrates the significant operating characteristics of the circuits. 相似文献
Theoretical transition energies, wavelengths, and oscillator strengths for E1 transitions from the low-lying , , and excited states to the and ground states are presented for ten ions isoelectronic with the chlorine atom. The multiconfiguration Dirac-Fock technique is used to generate the wave functions and obtain the energy levels. The effect of some correlation with 3d orbitals is noted. The relativistic forms of the electric-dipole operator are used to obtain values of oscillator strength corresponding to the nonrelativistic length and velocity forms. 相似文献
Heat shock protein 70 (Hsp70) family members are known as facilitators of immune responses by interacting with receptors on antigen-presenting cells leading to Hsp70-peptide uptake and antigen cross priming. Here, identification of human leukocyte antigen (HLA)-A24-restricted epitopes was achieved using peptide arrays for evaluation of their affinities to Hsp70 and HLA-A24 binding prediction tools. Using Hsp70 as the model antigen, the GYPVTNAVI and VFQHGKVEI peptides were identified as antigens. These peptides actually bound to HLA-A24 in the stabilization assay using T2-A*2402 cells, and induced a strong peptide-reactive cytotoxic T lymphocyte response in HLA-A24 transgenic mice after vaccination. 相似文献
An exploration of common rules (property motifs) in amino acid sequences has been required for the design of novel sequences and elucidation of the interactions between molecules controlled by the structural or physical environment. In the present study, we developed a new method to search property motifs that are common in peptide sequence data. Our method comprises the following two characteristics: (i) the automatic determination of the position and length of common property motifs by calculating the physicochemical similarity of amino acids, and (ii) the quick and effective exploration of motif candidates that discriminates the positives and negatives by the introduction of genetic programming (GP). Our method was evaluated by two types of model data sets. First, the intentionally buried property motifs were searched in the artificially derived peptide data containing intentionally buried property motifs. As a result, the expected property motifs were correctly extracted by our algorithm. Second, the peptide data that interact with MHC class II molecules were analyzed as one of the models of biologically active peptides with buried motifs in various lengths. Twofold MHC class II binding peptides were identified with the rule using our method, compared to the existing scoring matrix method. In conclusion, our GP based motif searching approach enabled to obtain knowledge of functional aspects of the peptides without any prior knowledge. 相似文献
The effects of a new latent accelerator and those of two common accelerators of 1-methyl imidazole and 2,4,6-tris(dimethylaminomethyl)phenol (DMP) have been studied in relation to the properties of dicyandiamide (dicy) cured epoxy resin and its prepregs with unidirectional carbon fiber. The new prepared accelerator is an adduct based on DMP (A_DMP). The results showed that the curing behavior of epoxy/dicy did not change when the appropriate amount of new accelerator was used. The amount of 5 phr of new latent accelerator is equal to the amount of 0.6 phr of DMP accelerator and by increasing the amount of new accelerator, the curing reaction of epoxy/dicy increased significantly. Viscosity build-up results and gel time measurements showed the high pot-life of resin system (epoxy/Dicy/A_DMP) and the high shelf-life of their prepreg. The results showed that the lap shear strength of sample containing 5 phr of the new accelerator (A_DMP5) was increased by 127% in comparison to the sample containing 0.6 phr of DMP. Transverse tensile strength and strain-at-break were increased by 27% and 31.7%, respectively. Transverse flexural strength, flexural strain-at-break and flexural modulus increased by 52%, 11% and 60%, respectively. On the other hand, fracture toughness and fracture energy increased significantly by 214% and 700%, respectively. This increase in mechanical properties was due to the bulkiness of the new latent accelerator acting as a toughening agent and also the good adhesion of fiber to the matrix as revealed by scanning electron microscopy.
The Journal of Supercomputing - Technology scaling has exacerbated the aging impact on the performance and reliability of integrated circuits. By entering into nanotechnology era in recent years,... 相似文献
The objective of this study was to investigate the impact of functional labelling on the consumers acceptability and purchase intentions of blueberry functional beverages (BFB). A 2‐day consumer acceptance test was conducted independently with functional information (n = 60) and without any information (n = 80). The presence of functional labelling did not influence the liking attributes of BFBs (P > 0.05). However, functional information positively affected consumer perception of health‐related perceptions associated with BFBs, such as ‘aiding eye health improvement’ and ‘eye fatigue relief’. Subjects perceived more health‐related perceptions when informed test was conducted. The first‐order effect was observed, in which the degree of the first‐order effect was greater for BFBs that had a thicker mouthfeel. Findings from the results can practically guide product developers and marketers in the functional drink industry by providing the strategy for how to evaluate reformulated functional beverages for the consumer acceptance test by warning a counter‐balanced sample presentation. 相似文献
Cerium oxide nanoparticles (CeO2-NPs) have been biosynthesized using the aqueous extract of aerial parts of Prosopis farcta. This plant contains phenolic compounds that function as reducing and capping agents. Biosynthesized particles have been characterized through the use of UV–vis, PXRD, TEM, FESEM, EDX, Raman and FTIR analysis. The UV–vis spectrum clearly showed absorption peak at 317?nm, which indicated the formation of spherical CeO2-NPs. It displayed in the FESEM and TEM images that the biosynthesized particles are uniformly and spherically shaped with a size of about 30?nm, while the EDX has clearly shown that only the elements Ce and O are present in the biosynthesized sample. Moreover, the Raman spectrum of synthesized nanoparticles has displayed a Ce-O stretching band at a measurement of 459?cm?1. The cytotoxic activity of biosynthesized nanoparticles against the HT-29 cancer cell line was studied using the MTT assay. All the concentrations of CeO2-NPs (0–800?µg/ml) showed non-toxic effects and thus, it can be suggested that these nanoparticles have the potential of being utilized in various fields of medicine, such as drug delivery. 相似文献
Cachexia is a complication of dismal prognosis, which often represents the last step of several chronic diseases. For this reason, the comprehension of the molecular drivers of such a condition is crucial for the development of management approaches. Importantly, cachexia is a syndrome affecting various organs, which often results in systemic complications. To date, the majority of the research on cachexia has been focused on skeletal muscle, muscle atrophy being a pivotal cause of weight loss and the major feature associated with the steep reduction in quality of life. Nevertheless, defining the impact of cachexia on other organs is essential to properly comprehend the complexity of such a condition and potentially develop novel therapeutic approaches. 相似文献
Wireless Networks - Single carrier-frequency division multiple access (SC-FDMA) is a multiple access technique in broadband wireless networks which has been adapted by 3GPP for uplink transmission... 相似文献