The Early voltage for abrupt double heterojunction bipolar transistors (DHBTs) has been calculated by using an effective junction velocity (Sc) at the base-collector heterojunction. Sc is obtained by self-consistently partitioning thermionic and quantum mechanical tunneling currents. Unlike single heterojunction bipolar transistors (SHBTs), the Early voltage varies very rapidly at low reverse bias and approaches the SHBT-limit at sufficiently high reverse bias. This is attributed to the presence of an energy barrier at the b-c heterojunction 相似文献
Here we demonstrate how sex allocation theory, one of the best verified areas of metazoan evolutionary biology, can be successfully applied to microparasitic organisms, by relating parasite prevalence and sex ratio in the Haemosporina. Members of this taxon, which includes Plasmodium, are parasitic protozoa with obligate sexual cycles in which dioecious haploid gametes drawn from the peripheral blood of a vertebrate host fuse within a dipteran vector. Consequently mating takes place within a highly subdivided population, a condition known to promote local mate competition and inbreeding and hence the evolution of female-biased sex ratios. We used an epidemiological framework to investigate mating patterns and sex ratio evolution within natural populations of these parasites. This phenotypic approach compliments more conventional biochemical approaches to the population genetics of parasitic protozoa. Data are presented which support a theoretical relation between transmission-stage sex ratio and prevalence across parasite populations. These results are consistent with a large inter-population variation in genetic structure and argue against sweeping generalizations about the clonality or otherwise of populations of these parasitic protozoa. 相似文献
Surfactant mixtures are used in many different industrial formulations. In this study, the mixed micelle formation behavior of 2 different cationic surfactants, namely dodecyltrimethylammonium bromide (DTAB) and benzyldimethylhexadecylammonium chloride (BDHAC), in the absence and presence of urea at various temperatures (298.15–318.15 K) was studied using the conductometric method. The attractive interaction between DTAB and BDHAC was estimated from the values of critical micelle concentration (CMC) and the CMC for ideal mixing (CMCid). Urea increases the CMC value as a result of the enrichment in the surface charge of the micelles/mixed micelles. The values of micellar mole fraction (X1Rub [Rubingh], X1M [Motomura], X1Rod [Rodenas]) and ideal micellar (X1id) of surfactant BDHAC were obtained by different models and are shown to exhibit the high contribution or effective involvement of BDHAC in mixed micelles and increase with increasing BDHAC mole fraction (α1). Activity coefficients (f1 and f2) were also evaluated from the relevant formula given in the literature. The negative values of the interaction parameters (β) show the attractive interaction among the studied components. Excess Gibbs free energy (?Gex) of micellization revealed that the stability of mixed micelles is higher in aqueous solution than in urea solution. The thermodynamic parameters, namely the Gibbs free energy change, enthalpy change, and entropy change (?Gom, ΔHom, and ?Som, respectively), were also calculated from the conventional standard equations. 相似文献
Indoor and cell‐edge coverage has been a major issue of concern for predeployed traditional macrocell (MC)–based homogeneous cellular network. Moreover, with the extensive increase of mobile users and developments of smart and highly specified devices, user demands and activities have led to huge cellular traffic. The key solutions to these that include network upgradation, overlaying of small cells (SCs), and scaling of resources have turned out to be the major causes for intercell interference (ICI) and energy‐efficiency degradation in heterogeneous cellular networks (HetCNs). In this paper, authors have tried to analyze the downlink performance metrics of cell boundary users with MCs overlaying SCs for three‐cell circular and seven‐cell sectorized networks through frequency reuse (FR) schemes. This paper also discusses the impact of ICI being encountered by users and the effect of SCs on the energy efficiency of the network. The locations for SCs are perceived where user density is large and demands high data rate such as at hot‐spot (HS) areas, railway stations, shopping malls, working farms, and organization. The performance metrics sum rate, average user throughput, and energy efficiency are compared by employing FR‐1 (full spectrum) and FR‐3 (three subbands) among MCs and deployed SCs. For both scenarios, simulation results and analyses depict that without SCs, utilization of FR‐1 results in performance degradation due to ICI effects. However, the downlink performance of cell boundary user and energy efficiency of the network could be enhanced by overlaying SCs near cell boundaries of preexisting MCs along with the allocation of FR‐1. 相似文献
In this article, the Cattaneo–Christov heat flux model is implemented to study non-Fourier heat and mass transfer in the magnetohydrodynamic flow of an upper-convected Maxwell fluid over a permeable stretching sheet under a transverse constant magnetic field. Thermal radiation and chemical reaction effects are also considered. The nonlinear partial differential conservation equations for mass, momentum, energy and species conservation are transformed with appropriate similarity variables into a system of coupled, highly nonlinear ordinary differential equations with appropriate boundary conditions. Numerical solutions have been presented for the influence of elasticity parameter (α), magnetic parameter (M2), suction/injection parameter \((\lambda ),\) Prandtl number (Pr), conduction–radiation parameter (Rd), sheet stretching parameter (A), Schmidt number (Sc), chemical reaction parameter \(\left( {\gamma_{c} } \right)\), modified Deborah number with respect to relaxation time of heat flux (i.e., non-Fourier Deborah number) on velocity components, temperature and concentration profiles using the successive Taylor series linearization method (STSLM) utilizing Chebyshev interpolating polynomials and Gauss–Lobatto collocation. The effects of selected parameters on skin friction coefficient, Nusselt number and Sherwood number are also presented with the help of tables. Verification of the STSLM solutions is achieved with existing published results demonstrating close agreement. Further validation of skin friction coefficient, Nusselt number and Sherwood number values computed with STSLM is included using Mathematica software shooting quadrature.
Over the past few years, taxanes have emerged as a new class of anticancer drugs. Docetaxel (DTX) the prototype of this class has been approved for the treatment of broad range of cancers. However, to date the commercial preparation of DTX (Taxotere®) is accompanying adverse side effects, intolerance, and poor solubility, which can be overcome by encapsulating them using solid lipid nanoparticles (SLNs). SLNs represent versatile delivery system of drugs with newer forms such as polymer–solid lipid hybrid, surface modified and long circulating nanoparticles bringing forth improved prospects for cancer chemotherapy. In this review, the authors have discussed the current uses of various SLNs formulations of DTX with key emphasis on controlled and site‐specific drug delivery along with enhanced antitumour activity elucidated via in vitro and in vivo studies. Furthermore, the review article highlights few approaches that can be used in combination with existing DTX‐loaded SLNs to supplement DTX drug delivery.Inspec keywords: nanoparticles, nanomedicine, drug delivery systems, biomedical materials, cancer, reviews, tumoursOther keywords: docetaxel‐loaded solid lipid nanoparticles, drug delivery system, taxanes, anticancer drugs, Taxotere, SLN encapsulation, polymer‐solid lipid hybrid, surface modified nanoparticles, long circulating nanoparticles, chemotherapy, review相似文献
A hydrostatic drivetrain transmits wind turbine energy to a generator. One hydrostatic transmission system (HTS) configuration utilizes a fixed displacement pump and a variable displacement motor. The system dynamics are captured in a nonlinear multi‐input multi‐output mathematical model. This paper introduces a decentralized control configuration based on this model to achieve two desired objectives: maximizing the harvested energy without direct measurement of wind and regulating the frequency of the generator without using power electronic converters. To accomplish these objectives, suitable pairing of control actuators and system responses are identified through nonlinear relative gain arrays (RGA) analysis. The pairing also provides a strong decoupling of control loops. So maximum power point tracking (MPPT) is achieved independently while the generator speed is regulated to maintain the frequency of generated power at 60 Hz. Simulation results demonstrate robust performance of MPPT and frequency regulation in the presence of uncertainties in the turbine and HTS model. We also demonstrate that the RGA paired input‐out control configuration offers superior performance over other possible input–output paired control configurations. 相似文献
This article reports a Microstrip design for low noise amplifier (LNA) using a packaged commercial GaN‐on‐SiC high electron mobility transistor (HEMT). A cascode configuration with an inter‐stage matching and an independent biasing technique was used. A lumped elements design was first developed, analyzed, and simulated in ADS. Then the design was implemented using microstrip technology and simulated using the momentum EM simulation in ADS. The LNA is easy to fabricate, has a low cost, and can be easily modified for other applications. The proposed GaN LNA showed a gain of 13.5 dB with a noise figure (NF) of 3 dB from 2.8 to 3.8 GHz. 相似文献
This article presents efficient parameters extraction procedure applied to GaN High electron mobility transistor (HEMT) on Si and SiC substrates. The method depends on combined technique of direct and optimization‐based to extract the elements of small‐signal equivalent circuit model (SSECM) for GaN‐on‐Si HEMT. The same model has been also applied to GaN‐on‐SiC substrate to evaluate the effect of the substrates on the model parameters. The quality of extraction was evaluated by means of S‐parameter fitting at pinch‐off and active bias conditions. 相似文献