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61.
Markel Vigo Amaia Aizpurua Myriam Arrue Julio Abascal 《New Review of Hypermedia and Multimedia》2013,19(3):223-244
Mobile web guidelines aim at providing developers with guidance to develop web content suitable for mobile devices. Automatic guideline review tools help evaluating conformance with respect to these guidelines in a systematic way. Yet, a number of mobile web guidelines refer to specific device features such as screen size, support for particular picture formats or support for pointing device. Since mobile devices are very diverse, in order to address the greater number of devices, guidelines adopt a device profile that may be considered as the common denominator device which is able to provide a satisfactory experience. While this approach is useful to define guidelines and make them more understandable, it introduces critical inaccuracies that make tool effectiveness decrease. This paper presents an application that considers specific device features in the evaluation process to produce device-tailored reports. As a result, higher rates of evaluation tool completeness, correctness and specificity are obtained. 相似文献
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Agriculture and household nutrition security—development practice and research needs 总被引:1,自引:0,他引:1
Aligning agriculture to improve household nutrition security requires agricultural research and development specialists to understand nutrition objectives and be able to contribute to integrated agriculture-health programs. This paper builds on discussions during the household nutrition security session at the second Global Conference on Agriculture Research for Development (GCARD2). To begin, there is a summary of the variety of ways essential nutrition knowledge can underpin nutrition-sensitive agriculture. Lessons for improving nutrition through agriculture, including: efficient and effective production of diversified, highly nutritious and biofortified foods, enhancing value chains to improve nutritional quality and food safety, and better policies and investments, are highlighted. Frequently missing in discussions on nutrition-sensitive agriculture are the requirements for capacity development and extension—critical requirements to scaling-out and sustaining improved nutrition outcomes through agriculture. Gender, local empowerment and other key issues are discussed, as are the opportunities for cost-effective approaches to be implemented and expanded. Finally, research gaps, approaches and priorities to improve practice and anticipate and respond to dynamic changes in biological and social systems are discussed. Four next steps are summarized: (1) align agricultural interventions with those in health services, water and sanitation and social protection; (2) implement approaches to accelerate learning for development implementation and policy and investment enabling; (3) build local and national capacity to adapt and innovate; and (4) empower women and disadvantaged communities, in which the burden and solutions to nutrition security are found. 相似文献
64.
Further Insight into Crystal Structures of Escherichia coli IspH/LytB in Complex with Two Potent Inhibitors of the MEP Pathway: A Starting Point for Rational Design of New Antimicrobials 下载免费PDF全文
Dr. Franck Borel Elodie Barbier Dr. Sergiy Krasutsky Dr. Karnjapan Janthawornpong Dr. Philippe Chaignon Dr. C. Dale Poulter Dr. Jean-Luc Ferrer Dr. Myriam Seemann 《Chembiochem : a European journal of chemical biology》2017,18(21):2137-2144
IspH, also called LytB, a protein involved in the biosynthesis of isoprenoids through the methylerythritol phosphate pathway, is an attractive target for the development of new antimicrobial drugs. Here, we report crystal structures of Escherichia coli IspH in complex with the two most potent inhibitors: (E)-4-mercapto-3-methylbut-2-en-1-yl diphosphate (TMBPP) and (E)-4-amino-3-methylbut-2-en-1-yl diphosphate (AMBPP) at 1.95 and 1.7 Å resolution, respectively. The structure of the E. coli IspH:TMBPP complex exhibited two conformers of the inhibitor. This unexpected feature was exploited to design and evolve new antimicrobial candidates in silico. 相似文献
65.
Hybrid palm oil (Elaeis oleifera × Elaeis guineensis) supplementation improves plasma antioxidant capacity in humans 下载免费PDF全文
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Pierre Lambelet Myriam Richelle Karlheinz Bortlik Federico Franceschi Andrea M. Giori 《Food chemistry》2009
Tomato-based foods rich in Z-lycopene are potentially more bioavailable and have greater bioefficacy compared to natural tomato products which mainly contain all-E-lycopene. To prepare a stable tomato extract with a high level of Z-lycopene, geometrical isomerisation of lycopene was studied in organic solvents either alone or in the presence of a tomato extract. Interconversion between the isomers was observed in all systems with 13Z-lycopene being the least stable. Heating a tomato extract containing mainly the all-E-isomer in ethyl acetate produced successively 13Z-, 9Z- and 5Z-lycopene. An isomerised tomato oleoresin with a minimal content of the most unstable 13Z-lycopene could be obtained by refluxing tomato oleoresin in ethyl acetate for 1 week. In this isomerised tomato oleoresin, total lycopene and lycopene isomer profiles were shown to remain constant for 1 year at room temperature. Accordingly, this product is a valid source of stable and potentially highly bioavailable lycopene. 相似文献
68.
Myriam Lamine Fatma Zohra Rahali Majdi Hammami Ahmed Mliki 《International Journal of Food Science & Technology》2019,54(8):2615-2623
The objective of this study was to investigate the chemical composition of the essential oils from citrus species, as well as their antioxidant and antimicrobial activities. By gas chromatography-mass spectrometry, we identified thirty-seven metabolites and a range of unique compounds, contributing to the discrimination of the species. Different biological potentialities were detected depending on the species supported the significant effect of the genetic factor. C. aurantium and C. limon exhibited the highest antioxidant activities which make them a potential source of natural preservative. C. limon exhibited the highest antibacterial activities and C. reticulata the highest antifungal activities. Essential oils extracted from these agro-wastes could serve as natural food preservatives to prevent food pathogens and then extending the shelf life. A set of potential metabolites could be implicated in the observed biological activity, underlying that the antimicrobial activity is a complex trait. 相似文献
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Krishna Vyncke Inge Huybrechts Myriam Van Winckel Magdalena Cuenca Garcia Idoia Labayen Frederic Gottrand Kurt Widhalm Catherine Leclercq Lars Libuda Yannis Manios Michael Sjostrom Denes Molnar Luis A. Moreno Marcela Gonzalez-Gross André Spinneker Fatima Perez de Heredia Maria Plada Stefaan De Henauw 《Lipids》2014,49(9):881-893
The present study aimed to assess the correlation between food and fatty acid (FA) intake and the serum phospholipid (PL) FA status in European adolescents and explored the percentage of variation in serum PL FA that could be attributed to dietary habits. Participants included 528 adolescents recruited in the HELENA Study. Dietary intake was assessed by two, self-administered, non-consecutive 24-h recalls. PL FA concentrations were measured in fasting venous serum samples. Reduced rank regressions were applied to examine the combined effect of food intakes. Results indicated that the variance in serum PL FA in adolescents, that could be explained by diet varied from 7.0 % for MUFA to 14.2 % for n-3FA. The variance in the long-chain n-3FA was mainly explained by fish intake but also by coffee and tea consumption. In conclusion this study indicated that dietary intake influences the serum PL FA status to a limited amount but that also other factors interfere. However, dietary intake is important as it is among those factors that could be modified. Furthermore, the results suggest that the overall dietary habits should be considered instead of only the consumption of single foods or nutrients, as the medium of the food or concomitant intake of foods and nutrients might interact and as such influence absorption or metabolism. 相似文献