Treatment for gynecologic cancer: A review of the effects on female sexuality.

Outlines treatments for gynecologic malignancies including radiation therapy or radical hysterectomy for cervical carcinoma, radical vulvectomy for vulvar carcinoma, and pelvic exenteration for recurrent disease. Research relating to their effects on female sexuality is critically reviewed. The relevant domains of treatment and patient characteristics that need assessment in this research area are also discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

IL-3 enhances both presentation of exogenous particulate antigen in association with class I major histocompatibility antigen and generation of primary tumor-specific cytolytic T lymphocytes

Recent studies have reported that APC can present particulate exogenous Ag in the context of class I MHC to CD8+ CTL, and our laboratory demonstrated that IL-3 could enhance CTL generation to exogenous Ag. In this paper, we wished to determine whether presentation of particulate Ag could be enhanced by IL-3. A T cell hybridoma, B3Z86/90.14 (B3Z) restricted to Ova/Kb, was used as an indicator for presentation of particulate Ag with class I MHC. When activated, this hybridoma expresses lacZ, allowing a simple colorimetric measurement of Ag-specific T cell stimulation. We demonstrated that bone marrow cells stimulated by IL-3 in vivo and in vitro exhibited significantly increased presentation of exogenous OVA linked to beads. Lysate from OVA-transfected line 1 murine lung adenocarcinoma cells (line 1/OVA) was also presented by IL-3-stimulated bone marrow cells, suggesting that these APC can process tumor fragments or debris. Studies using TAP1/2-deficient mice and Ag presentation inhibitors indicate that this exogenous Ag presentation is mediated via the conventional class I MHC pathway. Adoptive transfer of IL-3-stimulated bone marrow cells pulsed with lysate from line 1/OVA tumor cells into naive recipient mice led to the generation of a potent CTL response. These observations indicate that use of such cells may provide a new avenue for development of tumor vaccines.     

DC Servomotors?Modeling and Parameter Determination

Present methods of defining and measuring the parameters of separately excited dc servomotors are inadequate. Eight practical servomotor models are identified, and the parameters of each model are clearly defined. Testing procedures are given for determining a servomotor's model type and all the model parameters based only on the current response of the machine to a step input of armature voltage. Excellent agreement is obtained between the actual current responses of several servomotors and their predicted responses obtained from the corresponding mathematical models, indicating the efficacy of the technique.     

The application of the differential transform technique to point source problems of elasticity

The differential transform, being a formal integral transform in which integrations have been eliminated, is used to represent some point sources in operational form. The sources can also be represented by integrals or integral transforms. However, in order to solve some boundary value problems, it is simpler to use the operational representation than the integral or integral transform representation. Three examples illustrate the application of the differential transform and the operational representations.     

Longitudinal field assessment of equity effects on the performance of major league baseball players.

A time-series analysis was used to test predictions based on equity theory in a naturally occurring experiment involving 23 major league baseball players who began the 1976 season without contracts. It was posited that due to historical changes in the reserve system, these players would perceive themselves as undercompensated relative to salient others, and due to substantial reductions in salary as compared to their 1975 compensation, they would also perceive themselves as undercompensated relative to self-referents from the previous year. Such perceptions should produce lower performance. This hypothesis was supported for performance as measured by batting average, home runs, and runs batted in but not for runs scored. (16 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Solution of linear equations for small computer systems

A solution technique, based on Gauss elimination, is described which can solve symmetric or unsymmetric matrices on computers with small core and disk requirement capabilities. The method is related to frontal techniques in that renumbering of the nodes, such as in a finite element mesh, is not required, and the elimination is performed immediately after the equations for a particular node have been fully summed. Only two rows of the matrix need be on core at any step of the solution, but for more efficiency, the program presented here requires all the equations associated with two nodes to be on core. Minimum disk storage is achieved by storing only nonzero entries of the matrix, a single pointing vector for each node, regardless of the number of degrees-of-freedom, and the use of a single sequential file. Special care is taken of the boundary nodes where only the diagonal and the right-hand-side vector are stored. Assembly and elimination for these nodes are avoided completely. The performance of the program is compared with both symmetric and nonsymmetric frontal routines and is shown to be acceptable. The major merit of the method lies in the fact that it can be implemented on small minicomputers. The reduction of core and disk storage inevitably increases the solution time, but the decrease in the output file size also makes the back-substitution and resolution processes more efficient. In some cases, the total solution time can be shorter than for the frontal method due to this property.     

Is a rose always a rose? The role of social category exemplar change in attitude stability and attitude-behavior consistency.

Three experiments tested whether changes in social category exemplars affect attitude stability, attitude–behavior consistency, or attitude change. In Experiment 1, participants displayed greater attitude stability across 1 month, in several social categories, when they named the same rather than different exemplars. In Experiment 2, participants displayed greater attitude–behavior consistency toward each of 2 social categories when they named the same rather than different exemplars at behavior assessment and at attitude assessment. Participants who named a more likable exemplar behaved more positively, and those who named a less likable exemplar behaved more negatively, than their initial attitudes predicted. In Experiment 3, participants changed their attitudes in the predicted direction after estimating the height of an exemplar who was either more or less likable than the one they had earlier named. The results are interpreted as consistent with recent theory and research on attitude introspection, the matching hypothesis, and models of social judgment. (PsycINFO Database Record (c) 2011 APA, all rights reserved)