Optical activity and conformation of cobra neurotoxin

Cobra neurotoxin from Formosan cobra (Naja naja atra) venom is a compact globular protein having an intrinsic viscosity of 4.5 mL/g. The protein is stable in 7.5 M urea but can be denatured in 4.1 M guanidine hydrochloride or at elevated temperature (above 70 degrees C). Its conformation remains virtually the same in solvents of lower polarity than water such as 1,2-ethanediol or a mixed solvent of 1-propanol-1,2-ethanediol-water (5:1:1 by volume). The circular dichroism spectrum is "atypical" in water in that the peptide chromophores show a small negative circular dichroic (CD) band at 215 nm, a large positive one at 199 nm, and another large negative one below 190 nm. The CD pattern resembles to some extent that of a beta form but differs in both positions and magnitudes from the latter. It agrees qualitatively with the theoretical calculations of the reverse beta bends, suggesting that cobra toxin contains a considerable amount of beta turns and possibly a mixture of beta form and beta turns.     

Performance evaluation of priority CSMA-CA mechanism on ISA100.11a wireless network

The International Society of Automation recently released ISA100.11a as an open standard for reliable wireless networks for industrial automation. ISA100.11a uses the TDMA scheme in the medium access layer to provide deterministic services. However, ISA100.11a adopts the CSMA-CA mechanism with priorities for retransmission from failure on dedicated links, sporadic data, and network configuration.This paper evaluates ISA100.11a CSMA-CA by simulation, considering the effects of backoff procedures and priority settings to probability of collision and successful use of slots. It's demonstrated that a high number of priority classes enable better network utilization resulting in less number of packets exceeding their lifetime.     

Pre‐convolved Radiance Caching

The incident indirect light over a range of image pixels is often coherent. Two common approaches to exploit this inter‐pixel coherence to improve rendering performance are Irradiance Caching and Radiance Caching. Both compute incident indirect light only for a small subset of pixels (the cache), and later interpolate between pixels. Irradiance Caching uses scalar values that can be interpolated efficiently, but cannot account for shading variations caused by normal and reflectance variation between cache items. Radiance Caching maintains directional information, e.g., to allow highlights between cache items, but at the cost of storing and evaluating a Spherical Harmonics (SH) function per pixel. The arithmetic and bandwidth cost for this evaluation is linear in the number of coefficients and can be substantial. In this paper, we propose a method to replace it by an efficient per‐cache item pre‐filtering based on MIP maps — such as previously done for environment maps — leading to a single constant‐time lookup per pixel. Additionally, per‐cache item geometry statistics stored in distance‐MIP maps are used to improve the quality of each pixel's lookup. Our approximate interactive global illumination approach is an order of magnitude faster than Radiance Caching with Phong BRDFs and can be combined with Monte Carlo‐raytracing, Point‐based Global Illumination or Instant Radiosity.     

A multi-start iterated local search with tabu list and path relinking for the two-echelon location-routing problem

The two-echelon location-routing problem (LRP-2E) is raised by the design of transportation networks with two types of trips: first-level trips serving from one main depot a set of satellite depots, to be located, and second-level trips supplying customers from these satellites. In the proposed multi-start iterated local search (MS-ILS), three greedy randomized heuristics are used cyclically to get initial solutions. Each ILS run alternates between two search spaces: LRP-2E solutions, and travelling salesman (TSP) tours covering the main depot and the customers. The number of iterations allotted to a run is reduced whenever a known solution (stored in a tabu list) is revisited. MS-ILS can be reinforced by a path-relinking procedure (PR), used internally for intensification, as post-optimization, or both. On two sets with 24 and 30 LRP-2E instances, MS-ILS outperforms on average two GRASP algorithms and adding PR brings a further improvement. Our metaheuristic also surpasses a tabu search on 30 instances for a more general problem with several main depots. It is still effective on a particular case, the capacitated location-routing problem (CLRP): In a comparison with four published metaheuristics, only one (LRGTS, Prins et al., 2007) does better.     

Effect of engine-based thermal aging on surface morphology and performance of Lean NOx Traps

A small single-cylinder diesel engine is used to thermally age model (Pt + Rh/Ba/γ-Al₂O₃) lean NO_x traps (LNTs) under lean/rich cycling at target temperatures of 600 °C, 700 °C, and 800 °C. During an aging cycle, fuel is injected into the exhaust to achieve reproducible exotherms under lean and rich conditions with the average temperature approximating the target temperature. Aging is performed until the cycle-average NO_x conversion measured at 400 °C is approximately constant. Engine-based NO_x conversion decreased by 42% after 60 cycles at 600 °C, 36% after 76 cycles at 700 °C and 57% after 46 cycles at 800 °C. The catalyst samples were removed and characterized by XRD and using a microreactor that allowed controlled measurements of surface area, precious metal size, NO_x storage, and reaction rates. Three aging mechanisms responsible for the deactivation of LNTs have been identified: (i) loss of dispersion of the precious metals, (ii) phase transitions in the washcoat materials, and (iii) loss of surface area of the storage component and support. These three mechanisms are accelerated when the aging temperature exceeds 850 °C—the γ to δ transition temperature of Al₂O₃. Normalization of rates of NO reacted at 400 °C to total surface area demonstrates the biggest impact on performance stems from surface area losses rather than from precious metal sintering.     

Comportement électrocatalytique vis à vis de la réduction d'oxygène des oxydes mixtes AxByMn3−(x+y)O4

Résumé Les résultats expérimentaux présentés dans cette étude et ceux publiés précédemment montrent que l'électroréduction de l'oxygène se fait dans les sites actifs formés par des ions Mn⁴⁺, et que ceux de Mn³⁺ assurent le transport des électrons au sein du solide.

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From the results obtained in this study and those presented in previous publications, it can be deduced that the electroreduction of oxygen occurs via electron transfers at active sites created by Mn⁴⁺ ions and that Mn³⁺ ions contribute to the transport of the electrons through the bulk of the electrocatalysts.

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Certains de ces résultats ont fait l'object d'une communication enPoster à la réunion I.S.E. à Varna, Septembre 1977.

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A=Zn, Cr, Al;B = Ni, Cu; et 0 x,y 1.     

A sensitive method for the determination of amitriptyline and nortriptyline in human plasma

The kinetics of the male gametogenesis during the pregonadal period, prespermatogenesis, and "early" spermatogenesis has been described in detail. Concerning spermatogenesis in the adult individual reference is made to the articles of Courot, Hochereau-de Reviers and Ortavant (1970) and of Clermont (1972). The comparison of female and male gametogenesis (Fig. 1) shows that the "gonia stage" (asterisks) of the female germ cells is limited to one proliferation wave only, whereas the "gonia stage" of the male germ cells consists of a first proliferation wave, comparable to that of oogonia, a preparative phase to initiate spermatogenesis, and a second proliferation wave with renewal and differentiation of the spermatogonia. Germ cells in the "gonia stage" are highly sensitive towards ionising radiation and cytostatic drugs.     

A photonic technique for microwave frequency measurement

A novel photonic technique for microwave frequency measurement utilizing dispersion in a multichannel chirped fiber Bragg grating is presented. The technique is based on the amplitude comparison of power fading functions generated by double sideband modulated optical carriers propagating through a dispersive medium.     

Low-power-consumption and high-gain CMOS distributed amplifiers using cascade of inductively coupled common-source gain cells for UWB systems

A distributed amplifier with new cascade inductively coupled common-source gain-cell configuration is presented. Compared with other existing gain-cell configurations, the proposed cascade common-source gain cell can provide much higher transconductance and, hence, gain. The new distributed amplifier using the proposed gain-cell configuration, fabricated via a TSMC 0.18-/spl mu/m CMOS process, achieves an average power gain of around 10 dB, input match of less than -20 dB, and noise figure of 3.3-6.1 dB with a power consumption of only 19.6 mW over the entire ultra-wideband (UWB) band of 3.1-10.6 GHz. This is the lowest power consumption ever reported for fabricated CMOS distributed amplifiers operating over the whole UWB band. In the high-gain operating mode that consumes 100 mW, the new CMOS distributed amplifier provides an unprecedented power gain of 16 dB with 3.2-6-dB noise figure over the UWB range.     

Comments on “Capture and Retransmission Control in Mobile Radio”

For original paper by Zorzi and Rao, see IEEE J. Sel. Areas Commun., vol.12, no.8, p.1289-98 (1994 October)