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111.
Noriyuki Hayashi Hiroo Tarao Katsuo Isaka 《IEEJ Transactions on Electrical and Electronic Engineering》2009,4(4):523-533
Characteristics of power-frequency touch current inside an anatomically realistic human model of Japanese adult were numerically analyzed under various scenarios of current paths using a modified scalar potential finite difference (SPFD) method. Then, complex distributions of the current density in the model were visually illustrated. Results of the dosimetry of current density for excitable tissues indicates that the touch current within the reference level (0.5 mA) does not always satisfy the basic restriction of current density in the light of ICNIRP guideline for general public. Two sets of the internal body resistances Ri (i.e., 1130–1510Ω and 1460–1920Ω) are obtained, depending on the conductivity sets used. Although Ri considerably depends on the current scenario concerned, the highest values of Ri were obtained for the hand-to-hand scenario, regardless of the conductivity set. The inhomogeneous model always gives a higher value of Ri than does the homogeneous model that has a single conductivity equivalent to the weighted-average conductivity of the inhomogeneous model. It is found that the conductivity of muscle has significant influence on Ri, and that the resistance around the wrist and ankle is one of the predominant parameters to decide Ri. It is clearly shown that the current scenarios affect the pattern of the heart current flow, especially the direction of it, to a large extent. It is found that a current of 34–40% of touch current flows into the heart, and then the heart-current ratio is remarkably larger than old data. The heart-current factors of around 0.85 obtained are almost independent of the current scenarios, unlike those indicated in IEC60479-1, provided that the direction of heart current is ignored. © 2009 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. 相似文献
112.
Okochi M Hayashi H Ito A Kato R Tamura Y Sato N Honda H 《Journal of Bioscience and Bioengineering》2008,105(3):198-203
Heat shock protein 70 (Hsp70) family members are known as facilitators of immune responses by interacting with receptors on antigen-presenting cells leading to Hsp70-peptide uptake and antigen cross priming. Here, identification of human leukocyte antigen (HLA)-A24-restricted epitopes was achieved using peptide arrays for evaluation of their affinities to Hsp70 and HLA-A24 binding prediction tools. Using Hsp70 as the model antigen, the GYPVTNAVI and VFQHGKVEI peptides were identified as antigens. These peptides actually bound to HLA-A24 in the stabilization assay using T2-A*2402 cells, and induced a strong peptide-reactive cytotoxic T lymphocyte response in HLA-A24 transgenic mice after vaccination. 相似文献
113.
Mastitis is the most frequent and prevalent production disease in dairy herds in developed countries. Based on a milk somatic cell count (SCC) of either >300,000 or <200,000 cells/ml in this study, we defined the quarter as either inflamed or uninflamed, respectively. The electrical conductivity (EC) of milk was used as an indicator of udder epithelial cell damage. We determined the amount of H2O2 produced by utilizing a small molecular weight compound in milk, and examined the characteristics of H2O2 production and EC in milk from inflamed and uninflamed quarters. In cows with milk of delivery grade (control population), H2O2 production and EC were 3.6+/-1.3 nmol/ml and 5.4+/-0.4 mS/cm (mean+/-sd), respectively. In 37 inflamed quarter milk samples, the production of H2O2 was 1.9+/-1.0 nmol/ml and was significantly smaller than that in the control population (P<0.01). Production of H2O2 was moderately but significantly correlated with EC (r<-0.71). In 20 cows with inflamed quarters, the production of H2O2 in milk from inflamed quarters was significantly smaller than that in milk from uninflamed quarters (P<0.01). In 18 out of 20 cows, milk from inflamed quarters showed the smallest H2O2 production among all tested quarters in each cow. We conclude that inflammation caused a decrease in H2O2 production in milk. In this study, we present parameters for evaluating the lactoperoxidase/H2O2/thiocyanate antibacterial defence system in bovine milk. 相似文献
114.
Peerawut Yutthagowith Akihiro Ametani Naoto Nagaoka Yoshihiro Baba 《IEEJ Transactions on Electrical and Electronic Engineering》2011,6(4):324-330
This article presents calculations of tower surge responses and insulator voltages of an actual transmission tower including ground wires and phase wires. The partial element equivalent circuit (PEEC) method is applied as a simulation tool. Surge responses of the tower and insulator voltages calculated by the PEEC method are compared with electro magnetic transients program (EMTP) simulated results and experimental results collected from the literatures. The results calculated by the PEEC method agree well with the experimetal results, not only amplitudes but also waveshapes. © 2011 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. 相似文献
115.
Kinetically Stable Bicelles with Dilution Tolerance,Size Tunability,and Thermoresponsiveness for Drug Delivery Applications
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Dr. Noriyuki Uchida Dr. Noriko Nishizawa Horimoto Kuniyo Yamada Dr. Takaaki Hikima Dr. Yasuhiro Ishida 《Chembiochem : a European journal of chemical biology》2018,19(18):1922-1926
Mixtures of a phospholipid (1,2‐dipalmitoyl‐sn‐glycero‐3‐phosphatidylcholine, DPPC) and a sodium‐cholate‐derived surfactant (SC‐C5) at room temperature formed phospholipid bilayer fragments that were edge‐stabilized by SC‐C5: so‐called “bicelles”. Because the bilayer melting point of DPPC (41 °C) is above room temperature and because SC‐C5 has an exceptionally low critical micelle concentration (<0.5 mm ), the bicelles are kinetically frozen at room temperature. Consequently, they exist even when the mixture is diluted to a concentration of 0.04 wt %. In addition, the lateral size of the bicelles can be fine‐tuned by altering the molar ratio of DPPC to SC‐C5. On heating to ≈37 °C, the bicelles transformed into micelles composed of DPPC and SC‐C5. By taking advantage of the dilution tolerance, size tunability, and thermoresponsiveness, we demonstrated in vitro drug delivery based on use of the bicelles as carriers, which suggests their potential utility in transdermal drug delivery. 相似文献
116.
Relationship between degree of polymerization and optical and thermal properties of fluorene in polycarbonate polymers
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The influences of average degree of polymerization (Dp) and terminal group on thermal and optical properties of high refractive indexed transparent polymers were investigated. In this study, 9,9‐bis[4–(2‐hydroxyethoxy) phenyl] fluorene (BPEF) homo polymer was selected because it has been used as a representative monomer in high refractive index polymers as well as its unique property. BPEF has stable amorphous phase and reacts like a polymer. Its unique reaction allows continuous investigation from monomer to polymer. For hydroxyl‐terminated polymer, the refractive index (nd) decreased with increasing Dp. On the other hand, for a phenolic‐terminated group, nd increased with increasing Dp, and both converged to same value in high Dp region. As for glass transition temperatures (Tg), both terminal group series were increased as Dp increased. Though Tg of hydroxyl‐terminated polymer was higher than that of phenolic‐terminated polymer in the low Dp region, both converged to the same value and the inverse number of Tg had linear correlation against the weight percentage of carbonyl groups (CO), which was calculated by Dp. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134, 45042. 相似文献
117.
118.
Nagaoka K Hiraide I Sato K Yamagami T Nakamura T Yabutani T 《Radiation protection dosimetry》2007,126(1-4):585-589
Measurements of cosmic-ray neutron dose rates with a balloon in Sanriku, Japan (geographic location: 39 degrees N, 142 degrees E; corresponding geomagnetic latitude: 30 degrees N) were conducted at an altitude from 0.2 to 25 km on 25-26 August 2004 when solar activity was at an average level. Neutron dose rates given as ambient dose equivalent rates (H*(10)) were measured with high-sensitive neutron dose equivalent counters and electronic silicon personal dosimeters (EPDs). The neutron dose rates increased with increasing altitude, but they were saturated around 15-20 km and decreased with increasing altitude beyond 20 km. The neutron ambient dose equivalent rate was 1.5 microSv/h(- 1) at 20 km. Measured values were corrected for the deviation of the energy response of the dose equivalent counter from the fluence-to-ambient dose equivalent conversion coefficient, and the corrected values were very close to the calculated values with EPCARD. On the other hand, neutron measurements by the EPDs gave about 10 times overestimation because of the high sensitivity to cosmic-ray protons. 相似文献
119.
The micro gravity effect on the product selectivity of electrochemical reduction of CCl2 F2 (CFC-12) was studied using the metal supported gas diffusion electrodes (GDEs). Under the micro gravity, the current efficiency
for methane formation (the final product) increased, whereas that for CHClF2formation (a intermediate product) decreased at the Cu-supported GDE compared with the result under the normal gravity. This
result suggests that the convection has an influence on the product selectivity for electrochemical reaction. 相似文献
120.
In the vapor phase nitration of benzene with diluted nitric acid, we have succeeded in keeping a high nitration activity of the supported sulfuric acid catalyst for more than 2 months by co-feeding a trace amount of sulfuric acid (H2SO4/HNO3 = 1/5000 (wt. ratio)). The results after 60 days on-stream over 10 wt.%–H2SO4/SiO2 catalyst are as follows: yield of nitrobenzene (NB), 93% based on HNO3; selectivity of NB, 97% based on HNO3; productivity of NB (STY), 0.76 kg/kg cat h. These performances were demonstrated in bench scale experiments using molded silica or quartz supports. Finally, nitration reactions of toluene and chlorobenzene were conducted and compared with each other over several solid acid catalysts developed by us. 相似文献