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61.
New feasibilities are considered for the optical-correlation diagnostics of rough surfaces with different distributions of irregularities. The influence of deviations of the height surface roughness distribution from a Gaussian probability distribution on the accuracy of optical analysis is discussed. Possibilities for the optical diagnostics of fractal surface structures are shown, and a set of statistical and dimensional parameters of the scattered fields for surface roughness diagnostics is determined. Finally, a multifunctional measuring device for estimating these parameters is proposed. 相似文献
62.
63.
Van Houte H De Hoffmann E Van Veldhoven PP Mannaerts GP Carchon H Baes MI Declercq PE 《Lipids》2001,36(4):367-372
The goal of this study was to clarify the mechanism responsible for the catabolism of α-tocopherol. The vitamin, bound to
albumin, was incubated with rat liver microsomes and appeared to be broken down. Optimal production of the metabolite was
obtained when 1 mg of microsomal protein was incubated with 36 μM of α-tocopherol in the presence of 1.5 mM of NADPH. Chromatographic
and mass spectrometric analyses of the metabolite led to the conclusion that it consists of an ω-acid with an opened chroman
ring, although we could not perform nuclear magnetic resonance analysis to confirm this. Our data show that α-tocopherol is
ω-oxidized to a carboxylic acid and that this process can occur in rat liver microsomes in the presence of NADPH and O2. The oxidation to the quinone structure appears to be a subsequent event that may be artifactual and/or catalyzed by a microsomal
enzyme(s). 相似文献
64.
The introduction of the double bond in the sphingoid backbone of sphingolipids occurs at the level of dihydroceramide via an NADPH-dependent desaturase, as discovered in permeabilized rat hepatocytes. In the rat, the enzyme activity, which has
now been further characterized, appeared to be mostly enriched in liver and Harderian gland. By means of subcellular fractionation
of rat liver homogenates and density gradient separation of microsomal fractions, the desaturase was localized to the endoplasmic
reticulum. Various detergents were inhibitory to the enzyme, and maximal activities were obtained in the presence of NADPH
and when the substrate was complexed to albumin. In the presence of albumin, the chain length of the fatty acid of the truncated
dihydroceramides hardly affected the activity. Finally, in view of a likely evolutionary relationship between desaturases
and hydroxylases, the formation of hydroxylated intermediates was analyzed. No evidence for their presence was found under
our assay conditions.
In part presented at the Conférence Jacques Monod “Cell lipids: Topology, transport and signalling functions”, Aussois, May
1997 (France); Van Veldhoven, P.P. “Ceramide biosynthesis: Characterisation of the conversion of dihydroceramide to ceramide”.
Contributed equally to this study. 相似文献
65.
针对安钢两座380m3高炉,调查分析了其出铁现状和产生这种情况的原因,提出了强化炉前出铁的可行性措施.指出在6号380m3高炉大修采用大风机后,应该增加出铁次数或延长出铁时间,配备多组渣罐,改进炉前设备和耐火材料,提高出铁实操技能,强化管理.届时,两座380m3高炉平均日产有望突破1 600t,缓解集体公司缺铁现状. 相似文献
66.
67.
68.
3月23日.郎酒集团2011年全国经销商大会在成都召开。会上,郎酒集团董事长汪俊林宣布。2010年郎酒集团销售收入突破58亿元,同时2011年初郎酒提价工作顺利完成,未来十年郎酒将继续向着既定的“123工程”迈进,力争在2012年实现销售收入100亿元.2015年实现200亿元.2020年实现300亿元。 相似文献
69.
作为茅台股份公司个性化产品之一,仁酒自2007年面市以来一直保持稳健的发展步伐,到2009年,仁酒在前期市场建设、布局的基础上开始进入了新一轮的调整和布局。 相似文献