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排序方式: 共有1910条查询结果,搜索用时 15 毫秒
91.
Massimo Lorusso Alberta Aversa Diego Manfredi Flaviana Calignano Elisa Paola Ambrosio Daniele Ugues Matteo Pavese 《Journal of Materials Engineering and Performance》2016,25(8):3152-3160
Direct metal laser sintering (DMLS) is an additive manufacturing technique for the production of parts with complex geometry and it is especially appropriate for structural applications in aircraft and automotive industries. Aluminum-based metal matrix composites (MMCs) are promising materials for these applications because they are lightweight, ductile, and have a good strength-to-weight ratio This paper presents an investigation of microstructure, hardness, and tribological properties of AlSi10Mg alloy and AlSi10Mg alloy/TiB2 composites prepared by DMLS. MMCs were realized with two different compositions: 10% wt. of microsize TiB2, 1% wt. of nanosize TiB2. Wear tests were performed using a pin-on-disk apparatus on the prepared samples. Performances of AlSi10Mg samples manufactured by DMLS were also compared with the results obtained on AlSi10Mg alloy samples made by casting. It was found that the composites displayed a lower coefficient of friction (COF), but in the case of microsize TiB2 reinforcement the wear rate was higher than with nanosize reinforcements and aluminum alloy without reinforcement. AlSi10Mg obtained by DMLS showed a higher COF than AlSi10Mg obtained by casting, but the wear rate was higher in the latter case. 相似文献
92.
Paola Savoia Giovanni Cavaliere Elisa Zavattaro Federica Veronese Paolo Fava 《International journal of molecular sciences》2016,17(8)
Kidney transplant recipients frequently suffer from skin infections and malignancies, possibly due to the effects of long-term immunosuppressive therapy. While the relationships between immunosuppression and these pathological conditions have been widely investigated, little is known about the relative incidence and characteristics of inflammatory skin diseases in this type of patient. In this study, we analyze the incidence of a number of inflammatory cutaneous diseases in a cohort of patients who underwent kidney transplantation. Although our study shows a relatively low incidence of these pathologies in transplanted patients—in agreement with the general action of immunosuppressant therapies in reducing inflammation—we scored a different efficacy of the various immunosuppressive regimens on inflammatory and autoimmune skin diseases. This information can be key for designing immunosuppressive regimens and devising accurate follow-up protocols. 相似文献
93.
Marta Anna Szychlinska Francesca Maria Trovato Michelino Di Rosa Lucia Malaguarnera Lidia Puzzo Rosy Leonardi Paola Castrogiovanni Giuseppe Musumeci 《International journal of molecular sciences》2016,17(3)
Osteoarthritis is the most common human arthritis characterized by degeneration of articular cartilage. Several studies reported that levels of human cartilage glycoprotein chitinase 3-like-1 (CHI3L1) are known as a potential marker for the activation of chondrocytes and the progression of Osteoarthritis (OA), whereas lubricin appears to be chondroprotective. The aim of this study was to investigate the co-expression and co-localization of CHI3L1 and lubricin in normal and osteoarthritic rat articular cartilage to correlate their modified expression to a specific grade of OA. Samples of normal and osteoarthritic rat articular cartilage were analyzed by the Kellgren–Lawrence OA severity scores, the Kraus’ modified Mankin score and the Histopathology Osteoarthritis Research Society International (OARSI) system for histomorphometric evaluations, and through CHI3L1 and lubricin gene expression, immunohistochemistry and double immuno-staining analysis. The immunoexpression and the mRNA levels of lubricin increased in normal cartilage and decreased in OA cartilage (normal vs. OA, p < 0.01). By contrast, the immunoexpression and the mRNA levels of CHI3L1 increased in OA cartilage and decreased in normal cartilage (normal vs. OA, p < 0.01). Our findings are consistent with reports suggesting that these two glycoproteins are functionally associated with the development of OA and in particular with grade 2/3 of OA, suggesting that in the future they could be helpful to stage the severity and progression of the disease. 相似文献
94.
95.
A wave of recent cross-national research has pointed to the positive consequences for countries with high levels of “quality of government” (QoG), broadly defined, such as corruption, impartiality, and quality of public services. Yet the question of how QoG varies at the sub-national level is still widely overlooked, in particular with measures that are available over time. To address it, we present the third round of data from the regional European Quality of Government Index (EQI) survey corruption (D73), Europe (N44) governance (H11); sub-national (R50), time series (C22), collected in 2017 and built upon the opinions of 78,000 respondents in 193 regions from 21 European countries. The data provides several contributions to the literature. First, while the majority of QoG-type indices rely on expert assessments, the EQI relies on the assessments of citizens, who are the on-the-ground consumers of public services. Second, the data begins to show trends on QoG variation over time, as well as across European regions. Consequently, this data is the most comprehensive sub-national data to date; mapping of QoG within and across EU countries over the past decade. Building on previous rounds of data collected in 2010 and 2013, the 2017 EQI, which is published free for scholarly use, builds on both perceptions and experiences of citizens in public service areas such as health care, education, and law enforcement. This paper presents the results of the latest survey, improved with respect to the previous ones, discussion of trends across space and over time, as well as interesting avenues for future research that we detect across European regions. 相似文献
96.
Xavier Kurten (?–1840) was a Prussian landscape gardener who worked for the Savoy family in the Piedmont region of Italy in the first half of the nineteenth century. He designed or redesigned all royal parks, creating a specific style based on the English naturalistic garden approach. This research was performed with the aim of investigating the development of the English landscape garden in Italy. Historical documents relating to Kurten’s biography and his work in Piedmont, including plans, were collected and analysed. We analyse and discuss the features that characterised his work: the relationship between the landscape—garden—house, the path system, the use of water, the vegetation, and the garden as a productive landscape. Kurten’s style is compared with the projects of William Kent and Lancelot ‘Capability’ Brown. 相似文献
97.
Roberta Gentilini Sabrina Bozzini Fabiola Munarin Paola Petrini Livia Visai Maria Cristina Tanzi 《应用聚合物科学杂志》2014,131(2)
Extraction, purification, and gel preparation of Aloe Vera pectin and the evaluation of the biocompatibility of the pectin gels were studied, considering as end use as implantable materials for regenerative medicine. A. Vera was chosen as source of pectin, as this pectin was described to possess high molecular weight and a low degree of esterification. As the properties of pectins are strictly dependent upon the extraction methods in combination with the natural source, the extraction method was modified in order to optimize the yield of the final product, its purity, the duration of the process and the selection of non‐toxic chemical reagents. Changing the experimental conditions resulted in four different extraction processes and products with different physical and chemical characteristics. The optimal extraction resulted to be the process: with enzimatic deactivation by microwave and the use of sodium citrate as chelating agent the molecular weight of the pectin extracted was estimated to be 118 kDa and the 2.93% esterification degree. Cytocompatibility of pectin gels, prepared by ionotropic gelation, showing an improved cell adhesion if compared to commercial pectin. The results suggest that the extracted A. Vera pectins possess interesting properties to be exploited for the production of mechanically stable gels by ionotropic gelation and high rhamnose content matrices for application in regenerative medicine. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131, 39760. 相似文献
98.
Maurizio Martino Anna Paola Caricato Francesco Romano Tiziana Tunno Daniele Valerini Marco Anni M. Elisabetta Caruso Alessandro Romano Tiziano Verri 《Journal of Materials Science: Materials in Electronics》2009,20(Z1):435-440
We report on the deposition of soft matter thin films by Matrix Assisted Pulsed Laser Evaporation (MAPLE). In particular,
thin layers of biological material (Bovine Serum Albumin) and polymers (polyfluorene) for medical and optoelectronic applications,
were realized by laser irradiating a frozen solution containing a low amount of material diluted in a laser absorbing volatile
solvent. The depositions were carried out varying different parameters as solvent–solute concentration, solvent nature, laser
fluencies, etc. The optical, morphological, structural and spectroscopical properties were detected by means of different
analyses as FTIR, photoluminescence, AFM and SDS. 相似文献
99.
100.
Enzo Castellan Gloria Ischia Alberto Molinari Rishi Raj 《Metallurgical and Materials Transactions A》2013,44(10):4734-4742
We apply an in situ approach, whereby a polymer is incorporated into copper and evolves within the metal into the ceramic phase, to create a dispersion of hard particles in a metal. All constituents for the ceramic phase are contained within the organic polymer. The temperature for this polymer to ceramic conversion lies in the 1073 K to 1273 K (800 °C to 1000 °C) range. The process produces a nanoscale dispersion of the ceramic, which leads to high microhardness that remains unaltered at temperatures up to 1223 K (950 °C) (0.9T M). Apparently, the introduction of the ceramic phase leads to the retention of copper crystallite size of a few hundred nm, despite exposure to heat treatments at these very high temperatures. We call these materials polymer-derived metal-matrix composites. 相似文献