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排序方式: 共有1450条查询结果,搜索用时 265 毫秒
41.
Jorge Moreda–Piñeiro Elia Alonso-Rodríguez Vanessa Romarís-Hortas Antonio Moreda-Piñeiro Purificación López-Mahía Soledad Muniategui-Lorenzo Darío Prada-Rodríguez Pilar Bermejo-Barrera 《Food chemistry》2012,130(3):552-560
Bioavailability of total arsenic, toxic (arsenite, As(III); and arsenate, As(V)), and non-toxic (monomethylarsonic acid, MA; dimethylarsonic acid, DMA; arsenobetaine, AB; and arsenocholine, AC) arsenic species has been assessed in different raw seafood samples (white fish, cold water fish and molluscs) by using an in vitro model that combines simulated gastric and intestinal digestion/dialysis methods. Correlations between arsenic species bioavailability and seafood nutrient contents (fat and protein) have also been established. Total arsenic content in seafood samples, and dialyzable and non-dialyzable fractions, were analyzed by inductively coupled plasma – mass spectrometry (ICP–MS) after a microwave-assisted acid digestion treatment. The determination of the different arsenic species concentrations in the samples (after an optimised matrix solid phase dispersion (MSPD) approach) and in the dialyzable fraction was done by high performance liquid chromatography (HPLC) coupled to ICP-MS as a selective detector. Accuracy of the procedure (total arsenic determination) was assessed by analyzing DORM-2 and BCR-627 certified reference materials. The accuracy of the in vitro procedure was established through a mass-balance study. After statistical evaluation (95% confidence interval), good accuracy of the whole in vitro process, for total arsenic and for arsenic speciation, was observed. High dialyzability percentages for total arsenic and for arsenic species were found (i.e. from 84.6 ± 1.7% to 106 ± 2.6%). Bioavailability of arsenic exhibits a negative correlation with the fat content of the seafood. However, no correlation was observed between the bioavailable fraction of total arsenic and arsenic species and the protein content of the seafood studied. 相似文献
42.
43.
María Alba Pilar Formentín Josep Ferré-Borrull Josep Pallarès Lluís F Marsal 《Nanoscale research letters》2014,9(1):411
We report on the fabrication of polyelectrolyte multilayer-coated hollow silicon dioxide micropillars as pH-responsive drug delivery systems. Silicon dioxide micropillars are based on macroporous silicon formed by electrochemical etching. Due to their hollow core capable of being loaded with chemically active agents, silicon dioxide micropillars provide additional function such as drug delivery system. The polyelectrolyte multilayer was assembled by the layer-by-layer technique based on the alternative deposition of cationic and anionic polyelectrolytes. The polyelectrolyte pair poly(allylamine hydrochloride) and sodium poly(styrene sulfonate) exhibited pH-responsive properties for the loading and release of a positively charged drug doxorubicin. The drug release rate was observed to be higher at pH 5.2 compared to that at pH 7.4. Furthermore, we assessed the effect of the number of polyelectrolyte bilayers on the drug release loading and release rate. Thus, this hybrid composite could be potentially applicable as a pH-controlled system for localized drug release. 相似文献
44.
Metal‐Organic Framework Surface Functionalization: GraftFast Surface Engineering to Improve MOF Nanoparticles Furtiveness (Small 40/2018)
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45.
Valderrama Pilar Escabias Manuel Jiménez-Contreras Evaristo Valderrama Mariano J. Baca Pilar 《Scientometrics》2018,116(2):1203-1212
Scientometrics - In order to estimate the impact factor value for a journal in Dentistry, two sets of variables were considered in this study: the first takes in the longitudinal behavior of the... 相似文献
46.
Daniele da Silva Bastos Maria do Pilar Gonçalves Cristina Tristão de Andrade Kátia Gomes de Lima Araújo Maria Helena Miguez da Rocha Leão 《Food and Bioproducts Processing》2012,90(4):683-692
The aim of this work was to obtain a new stable food product from cashew apple juice encapsulated by spray-drying technique using chitosan–whey protein isolate systems. The materials were evaluated according to their physicochemical stability during storage at different conditions and characterized with respect to their particle size distribution and structure. Encapsulated commercial and natural juices showed homogenous and unimodal particle size distribution with diameters ranging from 0.2 to 5.0 μm and from 0.2 to 40.0 μm, respectively. Both juices demonstrated higher physicochemical stability for vitamin C and color measurements than their respective non-encapsulated juices. X-ray diffractograms evidenced that the powder juices after the 140th day of storage were still in amorphous state. These results indicate that the new product was effective in protecting sensitive compounds present in the food matrix and it was also able to remain stable throughout the study period. 相似文献
47.
Isaac Pinyol Jordi Sabater-Mir Pilar Dellunde Mario Paolucci 《Autonomous Agents and Multi-Agent Systems》2012,24(1):175-216
Computational trust and reputation models have been recognized as one of the key technologies required to design and implement
agent systems. These models manage and aggregate the information needed by agents to efficiently perform partner selection
in uncertain situations. For simple applications, a game theoretical approach similar to that used in most models can suffice.
However, if we want to undertake problems found in socially complex virtual societies, we need more sophisticated trust and
reputation systems. In this context, reputation-based decisions that agents make take on special relevance and can be as important
as the reputation model itself. In this paper, we propose a possible integration of a cognitive reputation model, Repage,
into a cognitive BDI agent. First, we specify a belief logic capable to capture the semantics of Repage information, which
encodes probabilities. This logic is defined by means of a two first-order languages hierarchy, allowing the specification
of axioms as first-order theories. The belief logic integrates the information coming from Repage in terms if image and reputation,
and combines them, defining a typology of agents depending of such combination. We use this logic to build a complete graded
BDI model specified as a multi-context system where beliefs, desires, intentions and plans interact among each other to perform
a BDI reasoning. We conclude the paper with an example and a related work section that compares our approach with current
state-of-the-art models. 相似文献
48.
Inés González‐Hidalgo Sancho Bañón José María Ros 《International Journal of Food Science & Technology》2012,47(4):674-681
The main by‐product from the table olive canning industry is the stone with some residual olive flesh. The purpose of this study was to evaluate the composition – phenolic compounds (hydroxytyrosol, tyrosol and oleuropein) and tocopherol – and the antioxidant activity in different fractions (flesh, stone and seed) from the table olive by‐product and the whole by‐product. The highest amounts of phenolic compounds (1710.0 ± 33.8 mg kg?1) as well as the highest antioxidant activity (8226.9 ± 9.9 hydroxytyrosol equivalents mg kg?1) were obtained in the seed. The highest amounts of hydroxytyrosol (854.8 ± 66.0 mg kg?1) and tyrosol (423.6 ± 56.9 mg kg?1) were found in the whole by‐product from the pepper stuffed olives, while the stone without seed had the maximum oleuropein content (750.2 ± 85.3 mg kg?1). α‐Tocopherol values were between 79.8 ± 20.8 mg kg?1 in the seed of the olive stone and 6.2 ± 1.2 mg kg?1 in the whole by‐product from the anchovy‐stuffed olives. In light of the results obtained, it would seem possible to use table olive by‐product as a source of natural antioxidants in foods, cosmetics or pharmaceutical products, thus contributing to diminishing the environmental impact of table olive by‐product and to its revalorisation. 相似文献
49.
50.
María del Pilar Monge Alejandra Paola Magnoli Maria Virginia Bergesio Nestor Tancredi Carina E. Magnoli 《Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment》2016,33(6):1043-1052
Aflatoxin B1 (AFB1) and fumonisin B1 (FB1) are mycotoxins that often co-occur in feedstuffs. The ingestion of AFB1 causes aflatoxicosis in humans and animals. Sodium bentonite (NaB), a cheap non-nutritive unselective sequestering agent incorporated in animal diets, can effectively prevent aflatoxicosis. Fumonisins are responsible for equine leukoencephalomalacia and porcine pulmonary oedema, and often have subclinical toxic effects in poultries. Fumonisin B1 and aflatoxin B1 are both strongly adsorbed in vitro on sodium bentonite. Co-adsorption studies, carried out with a weight ratio of FB1 to AFB1 that mimics the natural occurrence (200:1), showed that FB1 greatly decreases the in vitro ability of NaB to adsorb AFB1. The ability of two activated carbons to adsorb FB1 was also investigated. Both carbons showed high affinity for FB1. A complex behaviour of the FB1 adsorption isotherms with pH was observed. In vitro results suggest that under natural contamination levels of AFB1 and FB1, a mixture of activated carbon and sodium bentonite might be potentially useful for prevention of sub-acute aflatoxicosis. 相似文献