基于时变系数与社会认知模拟的粒子群优化

粒子群优化算法利用一群在可行区域内飞行的粒子来搜索最优解,具有易实现、收敛速度快的特点,然而也面临"早熟"的问题.提出了一种基于时变系数与社会认知模拟的粒子群优化算法.实验结果显示,在5种不同的标准化测试函数下,新算法较另外3种常用的算法优越.     

不完备信息系统中决策规则的不确定性表示

将完备信息系统中决策规则的不确定性度量引入到不完备信息系统中,充分讨论了条件属性值缺失时规则的不确定性度量表现为概率区间的特性,在此基础上给出了确信度和覆盖度的近似概率值,并利用确信度计算出规则对分类的反映程度.     

基于半实物仿真的电路板故障注入系统设计与实现

为了满足某型装备电路板测试性与诊断设计评价的需求,提出了一种基于DSP技术,利用半实物仿真方式实现的故障注入系统;该系统以TMS320C5416系列DSP器件为核心器件,利用CPLD扩展外部电路,主控计算机与该系统的通信通过USB接口实现,在故障注入时通过半实物仿真模式实现对电路板典型故障的注入;通过对典型电路的故障注入试验表明,该系统可靠性高,配置灵活,使用方便;目前该系统已经在工程实践中得到应用,效果明显,对提高电路板测试性设计水平具有重要意义。     

Performance index based learning controls for the partial non-regular systems using lifting technique

Deficiencies of the performance-based iterative learning control （ILC） for the non-regular systems are investigated in detail, then a faster control input updating and lifting technique is introduced in the design of performance index based ILCs for the partial non-regular systems. Two ldnds of optimal ILCs based on different performance indices are considered. Finally, simulation examples are given to illustrate the feasibility of the proposed learning controls.     

基于改进的基因表达式编程算法在作业车间调度问题中的应用

文章提出一种新颖的方法一改进的基因表达式编程算法来求解作业车间调度问题。作业车间调度问题是许多实际生产调度问题的简化模型,基因表达式编程算法结合了遗传算法和遗传编程的优点,具有更强的解决问题能力,对基因表达式编程算法进行改进使其在作业车间调度问题的应用上更加有效;最后应用一个实例来验证提出方法的有效性。     

Macrophage Membrane-Coated Nanoparticles Sensitize Glioblastoma to Radiation by Suppressing Proneural–Mesenchymal Transformation in Glioma Stem Cells

Radiotherapy is identified as a crucial treatment for patients with glioblastoma, but recurrence is inevitable. The efficacy of radiotherapy is severely hampered partially due to the tumor evolution. Growing evidence suggests that proneural glioma stem cells can acquire mesenchymal features coupled with increased radioresistance. Thus, a better understanding of mechanisms underlying tumor subclonal evolution may develop new strategies. Herein, data highlighting a positive correlation between the accumulation of macrophage in the glioblastoma microenvironment after irradiation and mesenchymal transdifferentiation in glioblastoma are presented. Mechanistically, elevated production of inflammatory cytokines released by macrophages promotes mesenchymal transition in an NF-κB-dependent manner. Hence, rationally designed macrophage membrane-coated porous mesoporous silica nanoparticles (MMNs) in which therapeutic anti-NF-κB peptides are loaded for enhancing radiotherapy of glioblastoma are constructed. The combination of MMNs and fractionated irradiation results in the blockage of tumor evolution and therapy resistance in glioblastoma-bearing mice. Intriguingly, the macrophage invasion across the blood-brain barrier is inhibited competitively by MMNs, suggesting that these nanoparticles can fundamentally halt the evolution of radioresistant clones. Taken together, the biomimetic MMNs represent a promising strategy that prevents mesenchymal transition and improves therapeutic response to irradiation as well as overall survival in patients with glioblastoma.     

增材制造技术在电机中的应用综述

增材制造技术(即3D打印)因具有高设计自由度、高材料利用率、高成形效率和精度等优势,逐渐成为高效轻质高功率密度电机设计与制造的研究热点。该文旨在对3D打印电机的性能及其应用作系统性综述。首先,对3D打印电机的发展脉络进行简要概括。其次,分别对3D打印铁心、磁钢、绕组,以及散热和机械支撑结构的研究现状进行总结,并与传统工艺加工的样件进行性能对比。随后,介绍了适用于增材制造的结构设计方法——拓扑优化。最后,根据目前的研究情况归纳了3D打印电机未来的发展趋势和面临的挑战。     

Comparison of gas sensing properties based on hollow and porous α-Fe<Subscript>2</Subscript>O<Subscript>3</Subscript> nanotubes

Hollow and porous α-Fe₂O₃ nanotubes were successfully synthesized by single nozzle electrospinning method followed by annealing treatment. The crystal structures and morphologies of the as-prepared materials were characterized by X-ray diffraction and scanning electron microscopy, respectively. The as-prepared materials were applied to construct gas sensor devices which gas sensing properties were further investigated. The obtained results revealed that porous α-Fe₂O₃ nanotube gas sensors exhibit a markedly enhanced gas sensing performance compared with hollow α-Fe₂O₃ nanotube gas sensors, which was about three times higher to 100 ppm acetone at 240 °C. Interestingly, hollow and porous α-Fe₂O₃ nanotube gas sensors both showed fast response–recovery time and good selectivity, but the porous ones possessed the shorter recovery time. The improved properties could be attributed to the unique morphology of porous nanotubes. Thus, further improvement of performance in metal-oxide-semiconductors materials could be realized by preparation the unique porous structures of nanotubes. Moreover, it is expected that porous metal-oxide-semiconductors nanotubes could be further design as promising candidates for gas sensing materials.