An inhibitor of DNA topoisomerase I from Xenopus laevis ovaries

A novel, heat-resistant and Pronase-sensitive, inhibitor of eukaryotic DNA topoisomerase I has been purified from Xenopus laevis ovaries. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of the most purified fraction revealed three bands with apparent molecular masses of 25, 28.5, and 33.5 kDa. The 25- and 33.5-kDa peptides recovered from an SDS-PAGE gel inhibited X. laevis DNA topoisomerase I. The purified inhibitor was specific to DNA topoisomerase I and did not inhibit other DNA enzymes tested. The inhibitor blocked the catalytic activity of DNA topoisomerase I by interacting with the enzyme, rather than by competing for binding sites on substrate DNA. Binding of DNA topoisomerase I to substrate DNA was blocked by the inhibitor, as was the cleavage reaction catalyzed by DNA topoisomerase I. Inhibition of DNA topoisomerase I was relieved by divalent cations Ca2+, Mg2+, or Mn2+.     

TNT-RDX混合废水处理的实验研究——生物-吸附法

介绍了在２５￣３５℃的温度下，用厌氧－兼氧－水生生物－吸附组合工艺处理ＴＮＴ和ＲＤＸ混合废水的方法，进行了日处理量为６０￣９００Ｌ的实验室放大实验。当ＴＮＴ和ＲＤＸ混合废水总浓度为４￣１２ｍｇ／Ｌ时，经过该工艺处理后可达到国家排放标准。其中厌氧－兼氧能去除废水中８０％以上的ＴＮＴ和ＲＤＸ，水生生物（水葫芦）对ＴＮＴ及ＲＤＸ也有一定的降解效果，最后用活性炭吸附可以实现深度处理。     

反常声电光频谱分析器

介绍了一种新型的反常声电光频谱分析器，它可以采用外加电压的办法改变器件的中心频率，扩大器件的频带宽度，并改善器件在频带宽度范围内的频率响应特性。用ＬｉＮｂＯ３制作了一个６０ＭＨｚ的反常声电光频谱分析器件，测试结果表明，器件中心频率可以由５０ＭＨｚ变到７０ＭＨｚ，频带宽度由原来的２６ＭＨｚ扩大到３７ＭＨｚ。     

Si_（1－x）Ge_x／Si定向耦合器的研制

在运用ＳｉＧｅ脊形波导单模条件和有效折射率法分析ＳｉＧｅ／Ｓｉ定向耦合器结构参数的基础上，采用分子束外延和各向异性腐蚀技术制备出Ｓｉ１－ｘＧｅｘ／Ｓｉ（ｘ＝０．０５）单模定向耦合器．在波长为１．３μｍ时，平均串音小于－１８．１ｄＢ，输出功率耦合效率达到９８．１％     

G.652光纤上的2.5Gbit／s色散受限系统

本文根据色散受限中继段长度的计算，对实际工程中１５５０ｎｍ波长２．５Ｇｂｉｔ／ｓ系统进行计算比较得出啁啾声引起的色散不容忽视，它使２．５Ｇｂｉｔ／ｓ成为色散受限系统。对１３１０ｎｍ波长６２２Ｍｂｉｔ／ｓ系统，当使用多纵模激光器时，往往也会成为色散受限系统。     

多级脉冲深穿透射孔技术

目前国内较先进的射孔工艺是增效射孔和三相流射孔,这2种射孔工艺均存在射孔深度和造缝深度浅的问题,尤其是对低渗油藏和纵向渗透率远大于横向渗透率的油藏,此造缝深度并不能满足油田生产的需要.介绍了一种新型的射孔技术,它是一种能进行深度射孔造缝的多级射孔技术,利用三级推进剂燃爆时产生峰值不连续的高温、高压气流,形成多级脉冲,多次冲击射孔孔眼前沿的裂缝,使其有效延伸至地层深处,从而较单独的射孔更能有效地增加油气产量.通过地面水泥靶的试验,证明了该射孔器的延缝功能和安全性;通过塘32等井的现场试验,证明该射孔技术对污染地层解堵有显著效果,可明显地降低地层破裂压力.     

A Novel Athermal 40-Channel DWDM Multi/Demultiplexer Based on the Combination of AWGs and Interleaver

An athermal 40-channel dense wavelength-division-multiplexing multi/demultiplexer using a novel combination technology is proposed. It consists of one 1times4 100- to 400-GHz spacing interleaver filter and four sub-arrayed-waveguide gratings (AWGs). The temperature-dependent wavelength shift of the combined device is successfully suppressed to 0.058 nm in the -20degC to 70degC temperature range. Moreover, the combined device's adjacent crosstalk (typically -35 dB) is much better than conventional AWGs (typically -25 dB).     

Reliability Analysis on the δ-Shock Model of Complex Systems

We investigate the delta-shock model of complex systems consisting of n i.i.d. components. We first obtain a general lifetime distribution for the delta-shock model of a general complex system by reducing the system to a linear combination of parallel systems. We then consider coherent system structures including series, parallel, and k-out-of-n, then derive some useful results including reliability bounds, bounds on the mean lifetime, limiting distributions, and Laplace-Stieltes transforms     

适用于高速长途DWDM系统的色散管理线路

对于高速长途密集波分复用（DWDM）传输，必需采用各种各样的色散补偿、色散管理技术，其中，交替使用正负色散光纤构成色散管理线路（DML）是可行的解决方案之一，在国际上已经取得显著进展，正成为人们关注的焦点，国内在这方面的研究报道还少见.文章以高速长途DWDM系统对传输线路的性能要求为基础，综述了有代表性的3种不同类型的DML的特点和最新进展。