LFSCA-UNet：基于空间与通道注意力机制的肝纤维化区域分割网络

目的 肝纤维化是众多慢性肝脏疾病的常见表现,如不及时治疗可发展为肝硬化甚至引发肝癌。肝纤维化的准确评估对临床治疗和预后评估等至关重要。目前,肝纤维化的诊断通过肝穿活检判断,有创且有并发症危险。为此,基于影像学的无创诊断方法越来越受到关注。本文提出一种基于通道注意力与空间注意力机制改进的用于肝纤维化区域的自动化分割U-Net （liver fibrosis region segmentation network based on spatial and channel attention mechanisms,LFSCA-UNet）。方法 依据Attention U-Net的改进方式,围绕U-Net的跳跃连接结构进行基于注意力的改进,在AG （attention gate）的基础上,加入以ECA （efficient channel attention）模块为实现方式的通道注意力机制,依据加入ECA的位置,LFSCA-UNet分为A、B、C共3个子型。结果 在肝数据集上与其他实验网络进行评估对比,本文提出的LFSCA-UNet网络结构平均Dice系数达到了93.33%,相比原始U-Net的Dice系数提高了0.539 6%。结论 本文方法将空间注意力机制与通道注意力机制进行结合,有效提高了肝纤维化区域的分割精度,对空间注意力模块使用通道注意力模块优化输入和输出,增加了网络的稳定性,提升了网络的整体效果。     

An SVD-based adaptive robust speech steganography using MDCT coefficient

Multimedia Tools and Applications - Speech is one of the essential ways of communication. The study of speech steganography provides great value in information security. To improve imperceptibility...     

基于多季相Sentinel-2影像的白洋淀湿地信息提取

白洋淀湿地是华北平原上重要的浅水湖泊湿地,对雄安新区绿色发展具有重要的生态价值。对白洋淀高度异质化的景观格局进行分类,能够为白洋淀湿地资源的遥感监测提供指导意义。针对湿地季节变化的特点,对白洋淀每个季节选取一期具有代表性的Sentinel-2影像,采用分类与回归树（CART）、支持向量机（SVM）、随机森林（RF）3种常用的机器学习分类器对15种季相组合实验方案进行分类,分析不同季相遥感影像及其组合对白洋淀湿地信息提取的优劣。结果表明：相较于使用单一季相影像分类,多季相影像的组合能够显著提高分类精度,春&夏季相组合能够得到最优的分类效果,相对单季影像总体分类精度提高了10.9%~25.5%,Kappa系数提高了0.09~0.29;SVM分类器的分类表现较为稳定,能够得到最高的平均分类精度,CART分类器在处理高维特征的能力不如随机森林和SVM;不同特征类型对湿地信息提取的贡献度从高到底依次是红边光谱特征、传统光谱特征、缨帽变换特征、主成分分析特征、纹理特征。实验成果能为湿地信息的遥感识别提供依据。     

基于侧重点聚类的数学表达式相似度计算方法

数学表达式相似度计算在信息检索中起着重要的作用,但现有的计算方法较少考虑数学表达式侧重点对相似度计算准确度的影响。为解决该问题,提出一种基于侧重点聚类的数学表达式相似度计算方法。针对侧重点主观性强的特点,定义表达式元素映射规则,使用[K]-means++算法对数学表达式聚类,从而归纳出数学表达式所属侧重点簇;以侧重点簇为依据,使用遗传算法对相似度计算方法中相关参数进行优化调节,以加强侧重点对相似度结果的影响。对比实验表明,该方法的相似度计算性能有所提高,得到的表达式结果列表更为理想。     

基于宽度学习的结构沉降预测

结构监测是确保工程结构建设在施工和运营阶段安全的关键因素,因此采用合理有效的预测模型对结构沉降监测数据进行科学准确的预测成为了当前结构沉降预测研究的重点。针对传统预测方法与深度学习方法用于结构沉降预测存在的预测精度不够高、模型结构复杂、训练耗时等问题,提出了一种基于宽度学习的结构沉降时间序列预测模型。通过实测地铁地下隧道沉降监测数据对宽度学习、人工神经网络、支持向量回归和深度置信网络-支持向量回归预测模型的预测结果进行对比分析。实验结果表明:宽度学习系统(broad learning system,BLS)应用于结构沉降预测具有良好的效果,其训练速度更快,预测精度更高。验证了所提出的宽度学习算法应用于结构沉降预测的可实施性和有效性。     

Der Umgang mit „second victims“ als organisationsethische Aufgabe

Background and purpose

Adverse events and medical errors can have severe consequences for patients (“first victims”), but also for the involved health care professionals (“second victims”). Don Berwick, former director of the Boston Institute for Healthcare Improvement (USA), highlighted the support for “second victims” as an “ethical issue”. But there is no clarity about what “ethical issue” implies. This article aims to clarify this question from the perspective of organizational ethics.

Method

Starting with data from the literature, challenges are described and evaluated from the perspective of organizational ethics.

Results

Evidence suggests that current approaches for supporting “second victims” are not sufficiently effective to help professionals to cope with the psychological consequences of adverse patient events and medical errors. This not only has negative consequences for the involved professionals, but can also put patient safety again at risk. In the light of these data, an organizational ethics approach is needed to comply with Don Berwick’s claim to consider the support of “second victims” as an “ethical issue”. This approach fosters the congruence of the organization’s values that are declared and those that are practiced. Its normative foundation is rooted in the organization’s duty of care both for the patients and for the employees.

Conclusions

Using organizational ethics it is possible to conceptualize and visualize the support for “second victims” as a binding component of the safety culture of the organization. It is translated into the organization’s obligation to raise the awareness for the phenomenon and to provide the resources necessary to deal effectively with it, e.?g., evidence-based ethical guidelines, standardized procedures, staff training, and low-threshold coaching programs.

     

PID auf Aneuploidie des Embryos?

Definition of problem

At least in some cases, testing for aneuploidy as part of preimplantation genetic diagnosis (PGD) can be medically useful for pregnancy care. The current legal situation in Germany seems to not generally exclude PGD to detect a maldistribution of chromosomes in an embryo, but testing would require approval by a PGD ethics committee on a case-by-case basis and a well-reasoned application by the concerned woman. This article examines ethically and legally whether fundamental reasons prevent PGD commissions from admitting requests to perform aneuploidy tests as part of PGD.

Arguments

Three constellations – each with differing ethical implications – can be distinguished in which testing for aneuploidy could be considered or could occur: Testing for aneuploidy can (i) be the main reason for in vitro fertilization (IVF), which in itself is not medically indicated; (ii) IVF is done as infertility treatment in which case PGD and aneuploidy testing could be done additionally; or (iii) PGD with IVF is indicated in order to prevent a congenital disease or chromosomal aberration leading to a diagnosis of aneuploidy as an incidental or additional finding. Ethical arguments which could lead to a general rejection of aneuploidy testing are the prevention of discrimination against people with aneuploidy, as well as the protection of embryos. These concerns oppose constellation (i), but do not apply to (ii) and (iii). Yet there are at least three ethical arguments in favour of an admissibility of a request for aneuploidy testing: the “good practice” of IVF, the duty to the emerging child and the parent’s right to have a voice in the discussion.

Conclusion

Aneuploidy testing as part of PGD is not ruled out by legal or ethical reasons and should be openly discussed by the relevant German ethics commissions.

     

Tod des Körpers oder Tod der Person?

Definition of the problem

Within the current philosophical debate on the adequate definition of human death, death is defined either as the death of the body or the death of the person. However, the application of these notions leads to several practical conflicts, which can be seen first and foremost in the brain-death debate and the discussions on how to increase organ donation.

Arguments

The conflicts are based in both a dualistic and objectivistic notion of the human being which are implied in both definitions of death. In order to solve these conflicts, we are in need of a nondualistic concept of human being which at the same time enables us to elaborate a first- and second-person perspective on death. On the basis of Helmuth Plessner’s philosophical anthropology, such an integrative concept of death can be developed.

Conclusion

Following this concept, it seems reasonable to abandon the brain-death criterion as the criterion for human death and to fundamentally reform the current information campaigns for organ donation.