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Wireless Personal Communications - Cloud computing is a growing technology where lot of heterogeneous resources are available and large amount of requests are submitted by the customers... 相似文献
83.
Evangelopoulos Xenophon Brockmeier Austin J. Mu Tingting Goulermas John Y. 《Machine Learning》2019,108(4):595-626
Machine Learning - We propose a set of highly scalable algorithms for the combinatorial data analysis problem of seriating similarity matrices. Seriation consists of finding a permutation of data... 相似文献
84.
85.
Yilin Yang Siddarth K. Achar John R. Kitchin 《American Institute of Chemical Engineers》2022,68(6):e17653
The degree of rate control (DRC) quantitatively identifies the kinetically relevant (sometimes known as rate-limiting) steps of a complex reaction network. This concept relies on derivatives which are commonly implemented numerically, for example, with finite differences (FDs). Numerical derivatives are tedious to implement, and can be problematic, and unstable or unreliable. In this study, we demonstrate the use of automatic differentiation (AD) in the evaluation of the DRC. AD libraries are increasingly available through modern machine learning frameworks. Compared with the FDs, AD provides solutions with higher accuracy with lower computational cost. We demonstrate applications in steady-state and transient kinetics. Furthermore, we illustrate a hybrid local-global sensitivity analysis method, the distributed evaluation of local sensitivity analysis, to assess the importance of kinetic parameters over an uncertain space. This method also benefits from AD to obtain high-quality results efficiently. 相似文献
86.
Scientometrics - The purpose of this study is to ascertain the suitability of GS’s url-based method as a valid approximation of universities’ academic output measures, taking into... 相似文献
87.
Geetha R. Madhusudhan V. Padmavathy T. Lallithasree A. 《Wireless Personal Communications》2019,108(3):1957-1976
Wireless Personal Communications - The majority of security systems for wireless sensor networks are based on symmetric encryption. The main open issue for these approaches concerns the... 相似文献
88.
D.R. Santos‐Peñate C.M. Campos‐Rodríguez J.A. Moreno‐Pérez 《International Transactions in Operational Research》2019,26(1):340-363
The ‐centroid problem or leader–follower problem is generalized considering different customer choice rules where a customer may use facilities belonging to different firms, if the difference in travel distance (or time) is small enough. Assuming essential goods, some particular customer choice rules are analyzed. Linear programming formulations for the generalized ‐medianoid and ‐centroid problems are presented and an exact solution approach is applied. Some computational examples are included. 相似文献
89.
Rachana R. Borkute Sren Woelke Gang Pei Anca Dorhoi 《International journal of molecular sciences》2021,22(9)
Neutrophils readily infiltrate infection foci, phagocytose and usually destroy microbes. In tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis (Mtb), neutrophils harbor bacilli, are abundant in tissue lesions, and their abundances in blood correlate with poor disease outcomes in patients. The biology of these innate immune cells in TB is complex. Neutrophils have been assigned host-beneficial as well as deleterious roles. The short lifespan of neutrophils purified from blood poses challenges to cell biology studies, leaving intracellular biological processes and the precise consequences of Mtb–neutrophil interactions ill-defined. The phenotypic heterogeneity of neutrophils, and their propensity to engage in cellular cross-talk and to exert various functions during homeostasis and disease, have recently been reported, and such observations are newly emerging in TB. Here, we review the interactions of neutrophils with Mtb, including subcellular events and cell fate upon infection, and summarize the cross-talks between neutrophils and lung-residing and -recruited cells. We highlight the roles of neutrophils in TB pathophysiology, discussing recent findings from distinct models of pulmonary TB, and emphasize technical advances that could facilitate the discovery of novel neutrophil-related disease mechanisms and enrich our knowledge of TB pathogenesis. 相似文献
90.