We report the palladium(II)‐catalyzed aerobic oxidative coupling of isocyanides with various (2‐aminophenyl)azoles using air as the stoichiometric oxidant. A diverse range of medicinally valuable azolo[c]quinazolines was obtained by this new approach.
The structural buildup during reticulation of thermoset systems containing reactive modifiers can strongly influence the final properties of such blends. This was studied by considering the rheological behavior during cure of an epoxy/amine thermoset system blended with reactive dendritic hyperbranched polymers (HBPs). Depending on the chemical structure of the HBP used in the blend, a phase separation could be observed. The onset and offset of the phase separation process could be detected by observing the evolution of the viscoelastic properties. The phase separation onsets obtained by rheological measurements were compared with the values obtained by traditional cloud point observations. Good agreement between the two techniques was observed. Hyperbranched polymers that did not phase separate during the curing process were used to study gelation phenomena and its dependence on the reactivity and functionality of the HBP. The gelation of the homogeneous blend system using the Flory‐Stockmayer theory was also modeled. This highlighted the influence of both functionality and reactivity of the components, and the appearance of co‐operative polymerization mechanisms in homogeneous blends. 相似文献
The effects of concentration of polyacrylic acid as a dispersant on rheological properties of aqueous alumina suspensions have been investigated under steady and oscillatory shear conditions. At solid volume fractions between 0.45 and 0.6, a high degree of particle stabilization is achieved when 0.2 wt% of polyacrylic acid is added. At lower dispersant concentrations, suspensions exhibit pronounced irreversible thixotropic behaviour, whereas at higher dispersant concentrations, time dependent effects on the flow properties are not detectable. When the saturation adsorption limit of the polyelectrolyte on Al2O3 is reached, further addition of the dispersant appreciably changes the flow behaviour, as well as the viscoelastic response of investigated suspensions. The data under steady shear are described by application of the generalized Casson model, and for the analysis of viscoelastic data the generalized Maxwell model is used. 相似文献
Nowadays, the construction sector is more and more oriented toward the promotion of sustainability in all its activities. The goal to achieve is the optimization of performances, over the whole life-cycle, with respect to environmental, economic and social requirements. According to the latest advances, the concept of sustainability applied to constructions covers a number of branches such as life-cycle costing, ecology, durability and even structural design. Several procedures and design tools have been implemented in the framework of international research. Indeed the current trend in civil engineering research is moving towards life-time engineering, with the aim to implement integrated methodologies to consider as a whole all the sustainability requirements according to time-dependent multi-performance-based design approaches. Following a general introduction of the concept of sustainability applied to constructions, this paper presents an overview of life-time engineering methodologies according to the current state-of-the-art. In particular the methods currently received by International Standards are discussed. A special focus is devoted to the durability design of metal structures with respect to the degradation phenomena able to impair the structural capacity over time. Finally a proposal towards an integrated approach to life-time engineering design of steel structures and needs for further advances are presented. 相似文献
Blastoschizomyces capitatus strains resistant to fluconazole were isolated in three cancer patients. All of the strains had identical genomic DNA restriction profiles. Our findings give evidence for the emergence of fluconazole-resistant B. capitatus and suggest a nosocomial acquisition emanating from a common source within the hospital environment. 相似文献
A mixed finite element scheme is used to simulate a consistent energy-transport model for electron transport in semiconductor
devices, free of any fitting parameters, formulated on the basis of the maximum entropy principle.
Simulations of silicon n+-n-n+ diodes, 2D-MESFET and 2D-MOSFET and comparisons with the results obtained with Monte Carlo direct simulation and with other
energy-transport models, known in literature, show the validity of the model and the robustness of the numerical scheme. 相似文献
A new motion-generation approach is proposed for wheeled mobile robots described by the unicycle kinematic model. This approach permits the generation of smooth continuous-acceleration controls using a dynamic path-inversion procedure that exploits the concept of G/sup 3/ -paths, i.e., Cartesian paths with third-order geometric continuity (both the curvature function and its derivative, with respect to the arc length, are continuous). The exposed steering method is well suited to be adopted for the robot's iterative steering within a supervisory control architecture for sensor-based autonomous navigation. A worked example illustrates the approach. 相似文献
In this paper, we present a formulation and numerical simulation for the phase shift of light as it is passed through dynamically forced optical fibers. A generalized representation for the induced phase shift, as well as a finite element model appropriate for an isotropic, arbitrarily oriented fiber is developed. These general expressions are then specialized to the particular case of a straight, finite length of fiber, which is forced normally along its entire length. Calculations are carried out for three quite different fiber configurations over a spectrum of frequencies, and the resulting phase and strain responses are presented and discussed 相似文献
