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排序方式: 共有700条查询结果,搜索用时 15 毫秒
41.
Losana MC Magnoni M Bertino S Procopio S Facchinelli A Sacchi E 《Radiation protection dosimetry》2004,111(4):419-422
In this study the air gamma dose rate map of Piemonte, a region in the North-West of Italy, was produced from gamma spectrometry soil data. Soil samples collected in 110 different sites of Piemonte were analysed with Hyperpure Germanium (HPGe) detectors (30% relative efficiency), which allow the evaluation of the activity concentrations of natural radionuclides and (137)Cs. Then, using the available mathematical models, the gamma absorbed dose rate in air due to radionuclides was calculated. The contribution of the cosmic radiation to the total absorbed dose rate, which depend on the site altitude was also evaluated and added to the soil contribution. Finally, the map of the whole region was obtained by fitting the dose rate values of the different sites with kriging algorithms. 相似文献
42.
Carbon-13 chemical shifts are reported for tetralin, hydrophenanthrenes and hydropyrenes and their alkyl substituted derivatives. Mono- and di- plus tri-aromatic fractions of hydrogenated phenanthrene and pyrene were also examined by carbon-13 n.m.r. and, wherever possible, the components in them identified. 相似文献
43.
De Luca S Ragone R Bracco C Digilio G Aloj L Tesauro D Saviano M Pedone C Morelli G 《Chembiochem : a European journal of chemical biology》2003,4(11):1176-1187
A cyclic CCK8 analogue, cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 (Dpr=L-2,3-diaminopropionic acid), has been designed on the basis of the NMR structure of the bimolecular complex between the N-terminal fragment of the CCK(A) receptor and its natural ligand CCK8. The conformational features of cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 have been determined by NMR spectroscopy in aqueous solution and in water containing DPC-d(38) micelles (DPC=dodecylphosphocholine). The structure of the cyclic peptide in aqueous solution is found to be in a relaxed conformation, with the backbone and Dpr29 side chain atoms making a planar ring and the N-terminal tripeptide extending approximately along the plane of this ring. In DPC/water, the cyclic peptide adopts a "boat-shaped" conformation, which is more compact than that found in aqueous solution. The cyclic constraint between the Dpr29 side chain and the CCK8 carboxyl terminus (Lys34) introduces a restriction in the backbone conformational freedom. However, the interaction of cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 with the micelles still plays an important role in the stabilisation of the bioactive conformation. A careful comparison of the NMR structure of the cyclic peptide in a DPC micelle aqueous solution with the structure of the rationally designed model underlines that the turn-like conformation in the Trp30-Met31 region is preserved, such that the Trp30 and Met31 side chains can adopt the proper spatial orientation to interact with the CCK(A) receptor. The binding properties of cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 to the N-terminal receptor fragment have been investigated by fluorescence spectroscopy in a micellar environment. Estimates of the apparent dissociation constant, K(d), were in the range of 70-150 nM, with a mean value of 120+/-27 nM. Preliminary nuclear medicine studies on cell lines transfected with the CCK(A) receptor indicate that the sulfated-Tyr derivative of cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 displaces the natural ligand with an IC(50) value of 15 microM. 相似文献
44.
The two-dimensional suffix tree of an n × n square matrix A is a compacted trie that represents all square submatrices of
A[11]. For the off-line case, i.e., A is given in advance to the algorithm, it is known how to build it in optimal time, for
any type of alphabet size [11],[18]. Motivated by applications in Image Compression[22[, Giancarlo and Guaiana [14] considered
the on-line version of the two-dimensional suffix tree and presented an O(n2 log2 n)-time algorithm, which we refer to as GG. That algorithm is a nontrivial generalization of Ukkonen's on-line algorithm
for standard suffix trees [23]. The main contribution in this paper is an O(log n) factor improvement in the time complexity
of the GG algorithm, making it optimal for unbounded alphabets [9]. Moreover, the ideas presented here also lead to a major
simplification of the GG algorithm. Technically, we are able to preserve most of the structure of the original GG algorithm,
by reducing a computational bottleneck to a primitive operation, i.e., comparison of Lcharacters, which is here implemented
in constant time rather than O(log n) time as in GG. However, preserving that structure comes at a price. Indeed, in order
to make everything work, we need a careful reorganization of another fundamental algorithm: Weiner's algorithm for the construction
of standard suffix trees [24]. Specifically, here we provide a version of that algorithm which takes linear time and works
on-line and concurrently over a set of strings. 相似文献
45.
Vittorio Sgrigna Francesco Altamura Simone Ascani Roberto Battiston Raffaele Bencardino Sandor Blasko Aurora Buzzi Marco Casolino Livio Conti Stefano Lucidi Mauro Minori Andrea Papi Piergiorgio Picozza Stefano Rossi Carlo Stagni David Zilpimiani 《Microgravity science and technology》2007,19(5-6):70-74
EGLE is a wide frequency band search- coil magnetometer designed and built at the Roma Tre University. It has been installed onboard the ISS by the Italian astronaut Roberto Vittori on April 25, 2005 within the LAZIO- EGLE experiment carried out during the ENEIDE Soyuz mission. The scope of the experiment is to test EGLE in space and to investigate geomagnetic field variations. The main applications of EGLE are the study of electromagnetic environment inside the ISS, the correlation of magnetic field data with particle fluxes detected by LAZIO particle detector, and the monitoring of ionospheric perturbations possibly caused by Earth seismic activity. Since continuous electromagnetic field measurements on board the ISS are important for diverse space applications, a magnetometer with a suitable design is requested. Appropriate solutions for these applications, which have been adopted by EGLE, are in particular the use of 1- Wire technology and the possibility to detect by means of a search- coil magnetometer a large portion of the ULF frequency band, usually measured by flux- gate probes. To investigate the topside ionosphere electromagnetic environment and stability of Van Allen radiation belts in relation with seismic and anthropogenic electromagnetic emissions, a specific satellite mission (the ESPERIA project) has been designed for the Italian Space Agency (ASI), and up to now a few instruments of its payload have been built and tested in space. One of them is exactly the EGLE search- coil magnetometer. The first magnetic observations performed by this instrument reveal to be promising and demand for a further and deeper analysis based on a longer time series of data. 相似文献
46.
Design of an enhanced access point to optimize TCP performance in Wi-Fi hotspot networks 总被引:1,自引:0,他引:1
In the last years, the number of Wi-Fi hotspots at public venues has undergone a substantial growth, promoting the WLAN technologies
as the ubiquitous solution to provide high-speed wireless connectivity in public areas. However, the adoption of a random
access CSMA-based paradigm for the 802.11 MAC protocol makes difficult to ensure high throughput and a fair allocation of
radio resources in 802.11-based WLANs. In this paper we evaluate extensively via simulations the interaction between the flow
control mechanisms implemented at the TCP layer and the contention avoidance techniques used at the 802.11 MAC layer. We conducted
our study considering initially M wireless stations performing downloads from the Internet. From our results, we observed that the TCP downlink throughput
is not limited by the collision events, but by the inability of the MAC protocol to assign a higher chance of accessing the
channel to the base station. We propose a simple and easy to implement modification of the base station’s behavior with the
purpose of increasing the TCP throughput reducing useless MAC protocol overheads. With our scheme, the base station is allowed
to transmit periodically bursts of data frames towards the mobile hosts. We design a resource allocation protocol aimed at
maximizing the success probability of the uplink transmissions by dynamically adapting the burst length to the collision probability
estimated by the base station. By its design, our scheme is also beneficial to achieve a fairer allocation of the channel
bandwidth among the downlink and uplink flows, and among TCP and UDP flows. Simulation results confirm both the improvement
in the TCP downlink throughput and the reduction of system unfairness. 相似文献
47.
Nanocapsules: Ultrastable Liquid–Liquid Interface as Viable Route for Controlled Deposition of Biodegradable Polymer Nanocapsules (Small 22/2016) 下载免费PDF全文
48.
Ultrastable Liquid–Liquid Interface as Viable Route for Controlled Deposition of Biodegradable Polymer Nanocapsules 下载免费PDF全文
Raffaele Vecchione Giulia Iaccarino Paolo Bianchini Roberto Marotta Francesca D'autilia Vincenzo Quagliariello Alberto Diaspro Paolo A. Netti 《Small (Weinheim an der Bergstrasse, Germany)》2016,12(22):3005-3013
Liquid–liquid interfaces are highly dynamic and characterized by an elevated interfacial tension as compared to solid–liquid interfaces. Therefore, they are gaining an increasing interest as viable templates for ordered assembly of molecules and nanoparticles. However, liquid–liquid interfaces are more difficult to handle compared to solid–liquid interfaces; their intrinsic instability may affect the assembly process, especially in the case of multiple deposition. Indeed, some attempts have been made in the deposition of polymer multilayers at liquid–liquid interfaces, but with limited control over size and stability. This study reports on the preparation of an ultrastable liquid–liquid interface based on an O/W secondary miniemulsion and its possible use as a template for the self‐assembly of polymeric multilayer nanocapsules. Such polymer nanocapsules are made of entirely biodegradable materials, with highly controlled size—well under 200 nm—and multi‐compartment and multifunctional features enriching their field of application in drug delivery, as well as in other bionanotechnology fields. 相似文献
49.
Raffaele Grasso Marco Cococcioni Baptiste Mourre John Osler Jacopo Chiggiato 《Expert systems with applications》2013,40(10):3886-3899
A decision support system for the optimal deployment of drifting acoustic sensor networks for cooperative track detection in underwater surveillance applications is proposed and tested on a simulated scenario. The system integrates sea water current forecasts, sensor range models and simple drifting buoy kinematic models to predict sensor positions and temporal network performance. A multi-objective genetic optimization algorithm is used for searching a set of Pareto optimal deployment solutions (i.e. the initial position of drifting sonobuoys of the network) by simultaneously optimizing two quality of service metrics: the temporal mean of the network area coverage and the tracking coverage. The solutions found after optimization, which represent different efficient tradeoffs between the two metrics, can be conveniently evaluated by the mission planner in order to choose the solution with the desired compromise between the two conflicting objectives. Sensitivity analysis through the Unscented Transform is also performed in order to test the robustness of the solutions with respect to network parameters and environmental uncertainty. Results on a simulated scenario making use of real probabilistic sea water current forecasts are provided showing the effectiveness of the proposed approach. Future work is envisioned to make the tool fully operational and ready to use in real scenarios. 相似文献
50.
Raffaele Conforti Marcello La Rosa Giancarlo Fortino Arthur H.M. ter Hofstede Jan Recker Michael Adams 《Journal of Systems and Software》2013
This article proposes an approach for real-time monitoring of risks in executable business process models. The approach considers risks in all phases of the business process management lifecycle, from process design, where risks are defined on top of process models, through to process diagnosis, where risks are detected during process execution. The approach has been realized via a distributed, sensor-based architecture. At design-time, sensors are defined to specify risk conditions which when fulfilled, are a likely indicator of negative process states (faults) to eventuate. Both historical and current process execution data can be used to compose such conditions. At run-time, each sensor independently notifies a sensor manager when a risk is detected. In turn, the sensor manager interacts with the monitoring component of a business process management system to prompt the results to process administrators who may take remedial actions. The proposed architecture has been implemented on top of the YAWL system, and evaluated through performance measurements and usability tests with students. The results show that risk conditions can be computed efficiently and that the approach is perceived as useful by the participants in the tests. 相似文献