Approach for a Standardized Methodology for Multisite Processing of 300-mm Wafers at R&D Sites

This paper describes the objectives and results of a joint European project named FLYING WAFER. The goal of the project was to provide a methodology for interlinking European R&D centers in micro and nano technologies to a distributed 300-mm CMOS R&D line. The project was carried out as a feasibility study. Therefore, the results provide a model and concept which has the potential of guaranteeing a safe and fast exchange of wafers and data between European R&D nodes to allow multisite processing. An implementation phase is planned as a second step.     

Short communication: Effects of different blood buffers administered in electrolyte solution to grain-fed veal calves experiencing diarrhea

Calf diarrhea can commonly lead to dehydration and metabolic acidosis due to the loss of fluid and electrolytes. The objective of this randomized clinical trial was to examine differences between treating male dairy calves experiencing diarrhea with either a basic bicarbonate electrolyte powder (BBP) composed of sodium bicarbonate (50.7 mmol/L); a mixed buffer powder (MBP) including sodium bicarbonate (33.8 mmol/L), sodium citrate (8.4 mmol/L), sodium acetate (6.3 mmol/L), and potassium citrate (1.9 mmol/L); or a liquid electrolyte (HAL) composed of sodium acetate (50.1 mmol/L). All 3 electrolyte solutions were standardized to provide 50 mmol/L blood buffers and a similarly strong ion difference (74.4, 74.9, and 82.6 mEq/L for BBP, MBP, and HAL, respectively). Holstein male calves (n = 80) were sourced from auction barns or local farms and delivered in 1 batch to the research facility. Calves were housed in individual pens and fed a 24% crude protein and 17% fat calf milk replacer (CMR) twice daily. Starter grain and water were offered ad libitum. Calves were randomly enrolled in 1 of the 3 treatments when experiencing either 2 consecutive days of a fecal score of 2 (runny, spreads easily) or 1 d with a fecal score of 3 (liquid devoid of solid material). Calves were blocked by the different enrollment criteria. The respective electrolyte solution was administered via esophageal tube 1 h after feeding CMR until the fecal score returned to 0 (normal consistency) or 1 (semiformed or pasty). Blood gas measurements were taken at 1, 8, and 24 h post the initial electrolyte feeding, and weight was measured at 1, 2, 7, 14, and 28 d postenrollment. Mixed repeated measure linear regression models were built to assess the effect that the electrolyte solutions had on the blood gas measurements and body weight. A total of 45 calves were enrolled in the trial with 14, 16, and 15 calves randomly assigned to the MBP, HAL, and BBP groups, respectively. As compared with BBP, MBP increased blood CO₂ at 8 and 24 h, increased bicarbonate at 24 h, increased base excess at 8 and 24 h, and increased anion gap at 24 h. Calves in the BBP and HAL groups noted more severe eye recession when compared with the MBP group. Average daily gain did not differ between treatments at any time point. Although a severe dehydration challenge was not present, which should be considered a limitation of the study, MBP improved the acid-base status of calves compared with BBP, whereas HAL performed similarly to MBP.     

Identification of biomarkers measured upon arrival associated with morbidity,mortality, and average daily gain in grain-fed veal calves

There is a strong need for management strategies that help reduce the incidence of disease and subsequent antimicrobial use in the veal industry. Biomarkers could serve as useful tools that allow producers to take preventative measures before clinical problems occur. The objective of this prospective cohort study was to identify biomarkers measured upon arrival associated with morbidity, mortality, and average daily gain (ADG) in grain-fed veal calves. Upon arrival at a grain-fed veal facility in Ontario, Canada, calves were weighed and health-scored using a standardized health-scoring system. Several metabolites were measured including creatine kinase (CK), cholesterol, haptoglobin, manganese, serum total protein, iron, cobalt, zinc, selenium, molybdenum, and IgG. Farm personnel treated calves according to their farm protocol and weighed them at 78 d after arrival. Performance, treatment, and mortality records from the facility were used for analysis. Multivariable Cox proportional hazard models were created to evaluate metabolic biomarkers associated with morbidity and mortality. A mixed linear regression model was created to determine biomarkers associated with ADG. A total of 992 male dairy calves were evaluated at arrival from January to December 2017. Of the calves evaluated, 74 calves (7.5%) died and 877 (88.4%) were treated for illness over the 11-wk period under observation. Higher levels of haptoglobin and molybdenum were associated with a greater hazard of morbidity, whereas higher weight upon arrival and higher levels of both CK and IgG were associated with a reduced hazard of morbidity. For mortality, higher weight upon arrival and higher levels of cholesterol and IgG were associated with a lower hazard of mortality occurring over the 78-d period of observation. Higher weight, cholesterol, copper, CK, iron, and IgG were associated with increased ADG, whereas increased zinc and haptoglobin were negatively associated with ADG. These results demonstrate that certain biomarkers could be used to identify high-risk calves when measured upon arrival at a veal facility. Future research should focus on determining the utility of these biomarkers to selectively target intervention strategies to improve ADG and reduce morbidity and mortality.     

The perspective of optical packet switching in IP dominant backboneand metropolitan networks

This article analyses the rationale and technical solutions for the use of optical packet switching techniques for both backbone and metropolitan applications. It also provides information on state-of-the-art technologies available for medium-term product development     

INFLUENCE OF SOLIDS MOISTURE CONTENT ON THE AVERAGE RESIDENCE TIME IN A ROTARY DRYER

The solids mean residence time in a rotary dryer is influenced by several variables such as dryer dimensions and solids characteristics. One of these characteristics, usually not taken into account in correlations proposed to estimate the mean residence time, is the solids feed moisture content. Although it is well known that the solids moisture content has a major impact on the ability of the solids to move along the rotary dryer, it does not enter as a parameter in available correlations. In this investigation, numerous experiments were performed in a pilot-scale rotary dryer to study the influence of solids moisture content and drying gas temperature on the mean residence time. Sand employed in cement makeup was used to perform these experiments. Results show that the mean residence time for a moisture content in the range of 8% to 12% is four times higher than for dry solids. The moisture content and the drying gas temperature influence significantly the shape of the residence time distribution curve.     

On complex eigenvalues and eigenvectors of the velocity gradient

According to Bertrand’s Theorem [J. Bertrand, Théorème relatif au mouvement le plus général d’un fluide, Comptes Rendus de l’Académie des Sciences de Paris, 66, (1867) 1127-1230], at any point in a continuum, at any time, there exists at least one infinitesimal material line element whose direction does not change, instantaneously. This direction is along an eigenvector of the velocity gradient tensor corresponding to a real eigenvalue. Corresponding to this eigenvalue there is also an infinitesimal material area element whose direction does not change, instantaneously. The Theorem does not address the question as to properties associated with complex eigenvalues of the velocity gradient. This note fills the gap. It is shown that corresponding to a complex eigenvalue there are two invariant ellipses, one associated with material line elements and the other with material areal elements.     

Some links between extremum spanning forests,watersheds and min-cuts

Minimum cuts, extremum spanning forests and watersheds have been used as the basis for powerful image segmentation procedures. In this paper, we present some results about the links which exist between these different approaches. Especially, we show that extremum spanning forests are particular cases of watersheds from arbitrary markers and that min-cuts coincide with extremum spanning forests for some particular weight functions.     

Performance and reliability of advanced High-K/Metal gate stacks (Invited Paper)

This paper provides a systematic study of mobility performance and Bias Temperature Instabilities (BTI) reliability in advanced dielectrics stacks. By studying a large variety of dielectric stacks we clearly demonstrate that mobility performance, interface defects Nit and Negative BTI reliability are strongly correlated. All are affected by nitrogen species N which is clearly identified as the main mobility killer when it reaches unintentionally the Si interface during the deposition of nitrided gates or the nitridation steps.     

Fast and Robust Normal Estimation for Point Clouds with Sharp Features

This paper presents a new method for estimating normals on unorganized point clouds that preserves sharp features. It is based on a robust version of the Randomized Hough Transform (RHT). We consider the filled Hough transform accumulator as an image of the discrete probability distribution of possible normals. The normals we estimate corresponds to the maximum of this distribution. We use a fixed‐size accumulator for speed, statistical exploration bounds for robustness, and randomized accumulators to prevent discretization effects. We also propose various sampling strategies to deal with anisotropy, as produced by laser scans due to differences of incidence. Our experiments show that our approach offers an ideal compromise between precision, speed, and robustness: it is at least as precise and noise‐resistant as state‐of‐the‐art methods that preserve sharp features, while being almost an order of magnitude faster. Besides, it can handle anisotropy with minor speed and precision losses.