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21.
Cold uniaxial pressing of powder into a green body is a common forming process used in ceramic and pharmaceutical industries.
Argillaceous particles are used as a model system to investigate granule failure during compaction. Indeed, the volume enclosed
between the die and punches is reduced and the powder consolidates until a final height is obtained or a prescribed compacting
pressure is reached. Desired properties of the green body are high strength, uniform density, no defects and fracture. In
this work an experimental investigation has been focused on the ‘cracking cone’ fracture in powder compacts. This includes
studies of crack propagation and determination of operating conditions to avoid the green body fracture. The numerical modelling
is implemented using a finite element method based on the Von Mises criterion. A case of simulation is presented to demonstrate
the ability of the model to compute the distribution of the relative stresses. 相似文献
22.
Z Abbas AH Khan SM Jafri SS Hamid SH Shah S Abid JA Qureshi 《Canadian Metallurgical Quarterly》1997,12(11):703-706
The authors compared in a controlled clinical study two groups of patients after a first renal transplantation treated by triple drug immunosuppressive therapy. In a group of 31 patients the triple combination comprised Sandimmune Neoral. In the control group there were 30 patients who received Sandimmune. No differences were found between the two groups as regards the effectiveness of this treatment and the authors did not confirm a lower incidence of rejections described in patients treated with Sandimmune Neoral. They confirmed, however, a lower interindividual variability of Cy-A levels assessed specifically in patients treated with Sandimmune Neoral. 相似文献
23.
Mohamed Abid Author Vitae 《Computers & Electrical Engineering》2007,33(4):231-232
24.
Serrano-Guisan S di Domenicantonio G Abid M Abid JP Hillenkamp M Gravier L Ansermet JP Félix C 《Nature materials》2006,5(9):730-734
The emerging field of spintronics explores the many possibilities offered by the prospect of using the spin of the electrons for fast, nanosized electronic devices. The effect of magnetization acting on a current is the essence of giant or tunnel magnetoresistance. Although such spintronics effects already find technological applications, much of the underlying physics remains to be explored. The aim of this article is to demonstrate the importance of spin mixing in metallic nanostructures. Here we show that magnetic clusters embedded in a metallic matrix exhibit a giant magnetic response of more than 500% at low temperature, using a recently developed thermoelectric measurement. This method eliminates the dominating resistivity component of the magnetic response and thus reveals an intrinsic spin-dependent process: the conduction-electron spin precession about the exchange field as the electron crosses the clusters, giving rise to a spin-mixing mechanism with strong field dependence. This effect appears sensibly only in the smallest clusters, that is, at the level of less than 100 atoms per cluster. 相似文献
25.
Dr. Eric Largy Wenbo Liu Abid Hasan Prof. David M. Perrin 《Chembiochem : a European journal of chemical biology》2013,14(16):2199-2208
Janus‐type nucleosides are heterocycles with two faces, each of which is designed to complement the H‐bonding interactions of natural nucleosides comprising a canonical Watson–Crick base pair. By intercepting all of the hydrogen bonds contained within the base pair, oligomeric Janus nucleosides are expected to achieve sequence‐specific DNA recognition through the formation of J‐loops that will be more stable than D‐loops, which simply replaces one base‐pair with another. Herein, we report the synthesis of a novel Janus‐AT nucleoside analogue, JAT, affixed on a carbocyclic analogue of deoxyribose that was converted to the corresponding phosphoramidite. A single JAT was successfully incorporated into a DNA strand by solid phase for targeting both A and T bases, and characterized through biophysical and computational methods. Experimental UV‐melting and circular dichroism data demonstrated that within the context of a standard duplex, JAT associates preferentially with T over A, and much more poorly with C and G. Density functional theory calculations confirm that the JAT structure is well suited to associate only with A and T thereby highlighting the importance of the electronic structure in terms of H‐bonding. Finally, molecular dynamics simulations validated the observation that JAT can substitute more effectively as an A‐analogue than as a T‐analogue without substantial distortion of the B‐helix. Overall, this new Janus nucleotide is a promising tool for the targeting of A–T base pairs in DNA, and will lead to the development of oligo‐Janus‐nucleotide strands for sequence‐specific DNA recognition. 相似文献
26.
Karim BENYAHI Youcef BOUAFIA Salma BARBOURA Mohand Said KACHI 《Frontiers of Structural and Civil Engineering》2018,12(4):577-593
The present study goes into the search for the safety domain of civil engineering structures. The objective is to show how a reliability-evaluation brought by a mechanical sizing can be obtained. For that purpose, it is necessary to have a mechanical model and a reliability model representing correctly the behavior of this type of structure.It is a question on one hand, to propose a formulation for the nonlinear calculation (mechanical nonlinearity) of the spatial structures in trusses, and on the other hand, to propose or to adapt a formulation and a modeling of the reliability. The principle of Hasofer-Lind can be applied, in first approach, for the reliability index estimation, scenarios and the probability of failure.The made check concerned metallic in truss structures. Finally, some structures are calculated using the method adapted by Hasofer-Lind to validate the probability approach of the reliability analysis. 相似文献
27.
T. Shimizu A.D. Abid G. Poskrebyshev H. Wang J. Nabity J. Engel J. Yu D. Wickham B. Van Devener S.L. Anderson S. Williams 《Combustion and Flame》2010,157(3):421-435
Catalytic ignition of methane over the surfaces of freely-suspended and in situ generated palladium nanoparticles was investigated experimentally and numerically. The experiments were conducted in a laminar flow reactor. The palladium precursor was a compound (Pd(THD)2, THD: 2,2,6,6-tetramethyl-3,5-heptanedione) dissolved in toluene and injected into the flow reactor as a fine aerosol, along with a methane–oxygen–nitrogen mixture. For experimental conditions chosen in this study, non-catalytic, homogeneous ignition was observed at a furnace temperature of ~1123 K, whereas ignition of the same mixture with the precursor was found to be ~973 K. In situ production of Pd/PdO nanoparticles was confirmed by scanning mobility, transmission electron microscopy and X-ray photoelectron spectroscopy analyses of particles collected at the reactor exit. The catalyst particle size distribution was log-normal. Depending on the precursor loading, the median diameter ranged from 10 to 30 nm. The mechanism behind catalytic ignition was examined using a combined gas-phase and gas-surface reaction model. Simulation results match the experiments closely and suggest that palladium nanocatalyst significantly shortens the ignition delay times of methane–air mixtures over a wide range of conditions. 相似文献
28.
Md. Mustafizur Rahman Salma Parvin Md. Hasanuzzaman Rahman Saidur Nasrudin A. Rahim 《传热工程》2013,34(15):1249-1261
The mixed convection flow and heat transfer characteristics inside a square ventilated cavity with a heat-generating solid circular body located at the center have been investigated numerically. The inlet opening is at the bottom of the left wall, while the outlet one is at the top of the right wall, and all the walls of the cavity are considered to be adiabatic. A Galerkin weighted residual finite element method is used to solve the governing equations of mass, momentum, and energy. The behavior of the fluid in the ranges of dimensionless cylinder diameter from 0.1 to 0.6 of the heat generating body, thermal conductivity ratio range from 0.2 to 50 between solid and fluid, and heat generating parameter range from 1 to 5 is described in detail. The medium considered is air with a Prandtl number of 0.71. It is found that the flow and temperature field is strongly dependent on the already-mentioned parameters for the ranges considered. The variation of the mean Nusselt number, the dimensionless average drag force, and the average temperature of the fluid versus Richardson number are presented for these parameters. 相似文献
29.
Salma Lasram Souheib Oueslati Ana Valero Sonia Marin Abdelwahed Ghorbel Vicente Sanchis 《Journal of food science》2010,75(2):M89-M97
ABSTRACT: This study investigated the effects of temperature (15 to 37 °C) and water activity (0.90 to 0.99) on the growth and production of ochratoxin A (OTA) by Aspergillus carbonarius cultured on synthetic nutrient medium (SNM) after 5 and 10 d of incubation. Total of 8 ochratoxigenic A. carbonarius, isolated from vineyards located in different regions of Tunisia, were used. Growth data were modeled by the flexible model of Baranyi and growth rates at each set of conditions were obtained. For both growth and OTA production, optimal water activity was 0.99; however, optimal temperature varied. The optimal temperature for growth was 30 °C. At 37 °C, the growth rate decreased significantly (P < 0.05). Maximum toxin production occurred at temperatures in the range of 15 to 25 °C with the optimum one depending on the isolate tested. Significant amounts of OTA were produced after only 5 d of incubation. Our results showed that A. carbonarius isolated from Tunisian grapes behave as those from European and Australian grapes, as reported in the literature, although some differences in trends for growth and OTA production were observed. 相似文献
30.
Behisht Ara Mian Muhammad Hira Amin Noori Robina Begum Salma Jabeen 《Polymer-Plastics Technology and Engineering》2016,55(14):1460-1473
In this research work, Zinc(II) and Aluminum(III)-IIP's were synthesized by optimizing the amount of methacrylic acid as monomer, divinylbenzene as cross-linker. The IIP's were functionalized with 8-hydroxy quinolone complexes of the two metal ions under thermal conditions by copolymerization with monomer and cross-linker. The IIP's and Non-IIP's were characterized using FT-IR, TGA, and SEM analysis. A quite remarkable difference in the size was observed of the polymers (Zn(II) 1.0 µm and Al(III) 0.1 µm). A stronger affinity was observed with IIP in comparison with Non-IIP at pH 3.1 and 4.5 for Zn(II) and Al(III) ions on their respective polymers. 相似文献