全文获取类型
收费全文 | 5420篇 |
免费 | 7篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 8篇 |
化学工业 | 81篇 |
金属工艺 | 13篇 |
机械仪表 | 14篇 |
建筑科学 | 14篇 |
矿业工程 | 3篇 |
能源动力 | 11篇 |
轻工业 | 37篇 |
水利工程 | 3篇 |
无线电 | 52篇 |
一般工业技术 | 105篇 |
冶金工业 | 4995篇 |
原子能技术 | 6篇 |
自动化技术 | 86篇 |
出版年
2022年 | 4篇 |
2021年 | 4篇 |
2020年 | 6篇 |
2019年 | 5篇 |
2017年 | 5篇 |
2016年 | 4篇 |
2015年 | 4篇 |
2014年 | 4篇 |
2013年 | 19篇 |
2012年 | 16篇 |
2011年 | 19篇 |
2010年 | 9篇 |
2009年 | 13篇 |
2008年 | 19篇 |
2007年 | 14篇 |
2006年 | 24篇 |
2005年 | 14篇 |
2004年 | 23篇 |
2003年 | 19篇 |
2002年 | 12篇 |
2001年 | 20篇 |
2000年 | 8篇 |
1999年 | 169篇 |
1998年 | 1551篇 |
1997年 | 895篇 |
1996年 | 594篇 |
1995年 | 341篇 |
1994年 | 274篇 |
1993年 | 312篇 |
1992年 | 54篇 |
1991年 | 70篇 |
1990年 | 63篇 |
1989年 | 78篇 |
1988年 | 64篇 |
1987年 | 73篇 |
1986年 | 61篇 |
1985年 | 73篇 |
1984年 | 9篇 |
1983年 | 16篇 |
1982年 | 25篇 |
1981年 | 23篇 |
1980年 | 41篇 |
1979年 | 8篇 |
1978年 | 11篇 |
1977年 | 96篇 |
1976年 | 206篇 |
1975年 | 14篇 |
1974年 | 10篇 |
1973年 | 4篇 |
1972年 | 3篇 |
排序方式: 共有5428条查询结果,搜索用时 15 毫秒
91.
DJ Benos BH Hahn JK Bubien SK Ghosh NA Mashburn MA Chaikin GM Shaw EN Benveniste 《Canadian Metallurgical Quarterly》1994,91(2):494-498
Infection by human immunodeficiency virus type 1 (HIV-1) is often complicated by a variety of neurological abnormalities. The most common clinical syndrome, termed acquired immunodeficiency syndrome (AIDS) dementia complex, presents as a subcortical dementia with cognitive, motor, and behavioral disturbances and is unique to HIV-1 infection. The pathogenesis of this syndrome is poorly understood but is believed to involve interactions among virally infected macrophages/microglia, astrocytes, and neurons. In this study, we show that exposure of primary rat and human astrocytes to heat-activated HIV-1 virions, or to eukaryotically expressed HIV-1 and HIV-2 envelope glycoproteins (gp120) stimulates amiloride-sensitive Na+/H+ antiport, potassium conductance, and glutamate efflux. These effects are blocked specifically by amiloride, an inhibitor of Na+/H+ antiport and by the selective removal of gp120 with immobilized monoclonal antibody. As a result of modulation of astrocytic function by gp120, the ensuing neuronal depolarization and glutamate exposure could activate both voltage-gated and N-methyl-D-aspartate-regulated Ca2+ channels, leading to increases in intraneuronal Ca2+ and neuronal death. These findings implicate the astrocyte directly in the pathogenesis of AIDS dementia complex. 相似文献
92.
Sheep pulmonary adenomatosis (SPA) is a contagious bronchiolo-alveolar carcinoma of sheep associated with an exogenous type D/B retrovirus known as jaagsiekte sheep retrovirus (JSRV). SPA represents a unique model for lung cancer, and studies on its aetiopathogenesis can provide further insight into the mechanisms of epithelial neoplasms. 相似文献
93.
In this paper we consider two results motivated by Livsic's well-known theorem that, for a hyperbolic system, a Hölder continuous function is determined, up to a coboundary, by its values around closed orbits. The first result relates to negative values around orbits and the second result to values for finitely many orbits. We also present some new results on maximizing measures and the boundary of the unit ball in the stable norm for a surface. 相似文献
94.
95.
96.
A procedure is described by which the length of a tendon at the onset of loading is determined objectively. The procedure includes the fitting of third-order polynomial functions on the load-elongation data. The onset of loading is detected by an increasing fit of the polynomial by selective data reduction of the initial part of the load-elongation curve. The procedure results in an objective and reproducible definition of the zero strain level of a tendon. 相似文献
97.
98.
We report the construction of a synthetic flavo-heme protein that incorporates two major physiological activities of flavoproteins: light activation of flavin analogous to DNA photolyase and rapid intramolecular electron transfer between the flavin and heme cofactors as in several oxidoreductases. The functional tetra-alpha-helix protein comprises two 62-aa helix-loop-helix subunits. Each subunit contains a single cysteine to which flavin (7-acetyl-10-methylisoalloxazine) is covalently attached and two histidines appropriately positioned for bis-his coordination of heme cofactors. Both flavins and hemes are situated within the hydrophobic core of the protein. Intramolecular electron transfer from flavosemiquinone generated by photoreduction from a sacrificial electron donor in solution was examined between protoporphyrin IX and 1-methyl-2-oxomesoheme XIII. Laser pulse-activated electron transfer from flavin to meso heme occurs on a 100-ns time scale, with a favorable free energy of approximately -100 meV. Electron transfer from flavin to the lower potential protoporphyrin IX, with an unfavorable free energy, can be induced after a lag phase under continuous light illumination. Thus, the supporting peptide matrix provides an excellent framework for the positioning of closely juxtaposed redox groups capable of facilitating intramolecular electron transfer and begins to clarify in a simplified and malleable system the natural engineering of flavoproteins. 相似文献
99.
Reexpansion pulmonary edema is a rare complication attending the rapid reexpansion of a chronically collapsed lung, such as occurs after evacuation of a large amount of air or fluid from the pleural space. The condition usually appears unexpectedly and dramatically-immediately or within 1 h in 64% of patients and within 24 h in the remainder. The clinical manifestations are varied; they range from roentgenographic findings alone in asymptomatic patients to severe cardiorespiratory insufficiency. The radiographic evidence of reexpansion pulmonary edema is a unilateral alveolar filling pattern, seen within a few hours of reexpansion of the lung. The edema may progress for 24-48 h and persist for 4-5 days. Human data on the pathophysiology of reexpansion pulmonary edema derive from small series of patients, case reports, and reviews of the literature. On the other hand, a larger body of data exists on experimental reexpansion pulmonary edema in cats, monkeys, rabbits, sheep, and goats. This review examines the clinical and experimental evidence for reexpansion pulmonary edema. In addition, we detail the historical background, clinical setting, treatment, and outcome of reexpansion pulmonary edema. 相似文献
100.
DJ MacGowan MN Janal WC Clark RN Wharton RM Lazar RL Sacco JP Mohr 《Canadian Metallurgical Quarterly》1997,49(1):120-125
BACKGROUND: Questionnaire-based surveys from several countries have consistently detected adverse health associated with home dampness and mould growth. METHODS: To test the validity of questions commonly used to indicate the presence of indoor mould, questionnaires were administered in 403 homes where dust samples were taken for viable fungi and air samples for ergosterol. RESULTS: Geometric mean concentrations of the total viable fungi were 255 (SE 116) x 10(3) CFU/g when mouldy odours were reported and 155 (SE 55) when odours were not reported (P = 0.01). Similarly, reported water damage was associated with a 50% increase (P = 0.06). Geometric mean concentrations of the predominantly indoor-source fungi, Aspergillus plus Penicillium, were twice as high when mould or mildew was reported than when not mentioned (P = 0.01). The presence of reported mould or water damage was unrelated to the presence of detectable levels of ergosterol. There was evidence for reporting bias: in the presence of low concentrations of viable fungi in dust, respondents reporting allergies were more likely to report visible mould growth (odds ratio [OR] = 1.8, 95% confidence interval [CI]: 0.9-3.5, P = 0.10. In the presence of elevated concentrations of dust fungi, respondents who smoked were less likely to report visible mould growth, (OR = 0.4, 95% CI: 0.2-0.7, P = 0.005). CONCLUSIONS: Reported mould, water damage, and mouldy odours were associated with elevated levels of indoor fungi. However, inaccuracy was high and there was evidence of a systematic reporting bias. Future research should concentrate on developing accurate objective measures of exposure to fungi, and then use this information to develop valid questionnaires. Currently, objective measures not questionnaires, are recommended to clarify the health effects of indoor fungi. 相似文献