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71.
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Donald E. Wasserman Stephen D. Hudock Jack F. Wasserman Logan Mullinix Steven J. Wurzelbacher Karl V. Siegfried 《人机工程学与制造业中的人性因素》2002,12(2):211-226
Vibration acceleration was triaxially and basicentrically measured, and digital‐audio‐tape‐recorded with each axis separately evaluated using both the ANSI S3.34 and ACGIH hand‐arm vibration (HAV) guidelines, for two pairs of pneumatic handheld grinders commonly used in metal fabrication operations including shipyards. Each tool pair consisted of a new and used grinder of the same model, performing the same simulated grinding tasks using new small grinding wheels, carbide burrs, wire brushes, and flap wheels. The results of this limited study showed, primarily, that the HAV standards were not exceeded, but there was a consistent tendency for the acceleration levels to increase between new and used tools, ranging from 11% to 66% on the Z‐axis, 13% to 66% on the Y‐axis, 44% to 58% on the X‐axis, when tasks involved using grinding wheels and carbide burrs (hard implements). The results were mixed when using disposable wire brushes and flap wheels (softer implements). The overall results suggest the need for and implementation of a regular tool vibration monitoring and maintenance program as a primary element to help maintain tool acceleration levels to a minimum. © 2002 Wiley Periodicals, Inc. 相似文献
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A method is described for obtaining information about the local order existing in monoatomic model solids or real materials based on their atomistic configurations. An efficient algorithmic implementation is provided. The shape of the polyhedra formed by ‘relevant’ neighbors of each atom enter a pattern recognition method to resolve the type of the (usually non-ideal) crystal structure to which atoms surrounded by their relevant neighbors belong: hexagonal close-packed, face-centered cubic or body-centered cubic. Further, this approach allows for the analysis of icosahedral structure which preferably occurs in amorphous solids. Results of a molecular dynamics computer simulation illustrate how this method can be applied to contribute to an understanding of the mechanical and structural properties of solids (i) undergoing a steady shear stress and (ii) upon increasing temperature. 相似文献
75.
L Siegfried M Kmetová V Janigová M Sasinka V Takácová 《Canadian Metallurgical Quarterly》1995,63(11):4543-4545
A total of 109 alpha-hemolytic and 104 nonhemolytic Escherichia coli isolates from children with dyspepsia and urinary tract infections were investigated for resistance to the bactericidal activity of human serum. A significantly higher proportion of serum resistance was found in alpha-hemolytic E. coli isolates than in nonhemolytic isolates (P < 0.01). An association between the titer of alpha-hemolysin produced and serum resistance was found. 相似文献
76.
Abstract Volatile organic compounds (VOCs) were measured in the air of 51 renovated rooms in Schleswig-Holstein. The buildings examined were of different types – private flats, schools, kindergartens, office buildings – the only common characteristic being that they had all been renovated within the last two years. Among the dominating substances in the 46/51 complaint cases were well-known substances such as alkylbenzenes or monoterpenes at high concentrations but also less common substances, i.e. those which have only recently been reported as indoor air contaminants, for example phenoxyethanol, 2-(2-butoxyethoxy)-ethylacetate (butyldiglycolacetate) or longifolene (Mohr, 1994) at remarkable concentrations. A tentative investigation was made to identify the simultaneous occurrences of the different substances, especially the uncommon ones with their potential sources, as well as health impairments. Finally, VOC emissions from two carpet glues, suspected during the investigations of playing a role as a potential source of the less common substances, were carefully measured under test chamber conditions. This additional laboratory experiment was made to verify the tendency shown in the field study that modern ecological building materials contain less volatile and less common substances but with increased indoor persistence, that could partially account for the increasing number of complaints in relation to the SBS phenomenon. 相似文献
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P Keohavong D Zhu TL Whiteside P Swalsky A Bakker EM Elder JM Siegfried S Srivastava SD Finkelstein 《Canadian Metallurgical Quarterly》1997,247(2):394-403
A sensitive method was developed and applied to examine the distribution of K-ras gene mutations in histologically differing areas of lung tissues obtained from lung cancer patients. This method, which combines polymerase chain reaction (PCR), mutation allele enrichment (MAE), and denaturing gradient gel electrophoresis (DGGE), allows detection of one K-ras mutant allele present in 10(4) to 10(5) wild-type alleles. It was applied to analyze mutations in codon 12 of the K-ras gene in 43 tissue sites microdissected from paraffin-embedded sections obtained from 8 archival cases of lung cancer, all previously shown to have codon 12 K-ras mutations by direct sequencing. In four cases, mutations were detected only in the tumor, while in the other four cases, the same mutations were also found in tissues adjacent to tumors, using the MAE + DGGE method. No mutations were detected among normal-appearing cells in areas distant from the tumors in any of the cases studied. These findings demonstrate that K-ras mutations can be detected at low frequencies in normal-appearing cells from tissues adjacent to the tumor in some lung cancer cases. In addition, this approach also allowed detection of multiple mutations in colorectal tissues obtained from colorectal cancer patients. Thus, the MAE + DGGE method may be applicable to study of K-ras mutations in premalignant or morphologically suspicious lesions in bronchial mucosa or other types of human cancer. 相似文献
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80.
Siegfried Bauer Simona Bauer‐Gogonea Ingrid Graz Martin Kaltenbrunner Christoph Keplinger Reinhard Schwödiauer 《Advanced materials (Deerfield Beach, Fla.)》2014,26(1):149-162
Scientists are exploring elastic and soft forms of robots, electronic skin and energy harvesters, dreaming to mimic nature and to enable novel applications in wide fields, from consumer and mobile appliances to biomedical systems, sports and healthcare. All conceivable classes of materials with a wide range of mechanical, physical and chemical properties are employed, from liquids and gels to organic and inorganic solids. Functionalities never seen before are achieved. In this review we discuss soft robots which allow actuation with several degrees of freedom. We show that different actuation mechanisms lead to similar actuators, capable of complex and smooth movements in 3d space. We introduce latest research examples in sensor skin development and discuss ultraflexible electronic circuits, light emitting diodes and solar cells as examples. Additional functionalities of sensor skin, such as visual sensors inspired by animal eyes, camouflage, self‐cleaning and healing and on‐skin energy storage and generation are briefly reviewed. Finally, we discuss a paradigm change in energy harvesting, away from hard energy generators to soft ones based on dielectric elastomers. Such systems are shown to work with high energy of conversion, making them potentially interesting for harvesting mechanical energy from human gait, winds and ocean waves. 相似文献