Fatty acid and carotenoid composition of egg yolk as an effect of microalgae addition to feed formula for laying hens

Hens were fed five diets based on rapeseed/corn oils with or without addition of the marine microalgae, Nannochloropsis oculata. Colours of egg yolk, fatty acid profiles in phospholipid (PL) and triacylglycerol (TAG) fractions and carotenoid contents were analysed. The major effects on yolk fatty acid composition were observed in the PL fraction with changes in 18:2n − 6, 18:3n − 3, 20:4n − 6, 20:5n − 3 and 22:6n − 3. The highest amounts of eicosapentaenoic acid and docosahexaenoic acid were obtained from the diet containing 20% N. oculata, whereas the highest arachidonic acid content in yolk was from the corn oil diet. In addition, colour (a* value) and carotenoid content increased when N. oculata was included in the diet. Long chained fatty acids were almost exclusively present in the PL fraction of yolk. This study shows that fatty acid composition and carotenoid content of egg yolk are improved by addition of N. oculata in laying hen diet.     

The effect of moisture on the dynamical mechanical properties of bacterial cellulose/glucuronoxylan nanocomposites

The plant cell wall possesses unique material properties due to its hierarchical organisation. In order to biomimic a native structure like a plant cell wall, a model system consisting of microfibrillar cellulose, produced by the gram-negative bacteria Acetobacter xylinum, and a glucuronoxylan matrix derived from aspen holocellulose was constructed. The glucuronoxylan was extracted from delignified aspen (Populus tremula) wood chips using DMSO to preserve its native chemical composition. Dynamic mechanical analysis (DMA) measurements performed with moisture scans showed a moisture-induced softening of delignified aspen wood fibres due to the plasticization of glucuronoxylan. A similar result was observed for the model system. However, the softening behaviour of the delignified aspen fibre and the model system was not identical, most probably due to differences in spatial organisation of the components. Dynamic FTIR-studies indicated that interactions between the cellulose and the glucuronoxylan exist in the aspen holocellulose while the components in the nanocomposite appear to be more isolated.     

Safety evaluation of slender high-strength concrete columns under sustained loads

A realistic analysis of the reliability of slender high-strength concrete (HSC) columns must include the long-term effects of sustained loads. In this paper, the long-term reliability of eccentrically loaded slender HSC columns under sustained loads is evaluated. The reliability of slender reinforced concrete columns representing normal-strength concrete and HSC is investigated. Since most of the variables involved in column design (material properties, geometric characteristics, loads, etc.) are random, probabilistic methods are used in the analysis. The effects of the concrete compressive strength, amount of longitudinal steel, load eccentricity, and slenderness ratio on the column reliability are investigated. It was found that all these factors have a considerable impact on the resulting column reliability.     

Intestinal transport of gentamicin with a novel, glycosteroid drug transport agent

PURPOSE: The objective was to investigate the ability of a glycosteroid (TC002) to increase the oral bioavailability of gentamicin. METHODS: Admixtures of gentamicin and TC002 were administered to the rat ileum by injection and to dogs by ileal or jejunal externalized ports, or PO. Bioavailability of gentamicin was determined by HPLC. 3H-TC002 was injected via externalized cannulas into rat ileum or jejunum, or PO and its distribution and elimination was determined. The metabolism of TC002 in rats was evaluated by solid phase extraction and HPLC analysis of plasma, urine and feces following oral or intestinal administration. RESULTS: The bioavailability of gentamicin was substantially increased in the presence of TC002 in both rats and dogs. The level of absorption was dependent on the concentration of TC002 and site of administration. Greatest absorption occurred following ileal orjejunal administration. TC002 was significantly more efficacious than sodium taurocholate, but similar in cytotoxicity. TC002 remained primarily in the GI tract following oral or intestinal administration and cleared rapidly from the body. It was only partly metabolized in the GI tract, but was rapidly and completely converted to its metabolite in plasma and urine. CONCLUSIONS: TC002 shows promise as a new drug transport agent for promoting intestinal absorption of polar molecules such as gentamicin.     

Characterization and quantification of folates produced by yeast strains isolated from kefir granules

For the first time to our knowledge, distribution and content of individual folate forms in kefir yeast strains were investigated. This was done using a validated method based on reversed-phase high performance liquid chromatography (HPLC) with fluorescence and diode array (DAD) detection. Eight kefir yeast strains, belonging to different Candida and Saccharomyces species, were isolated from Russian kefir granules. They were grown in synthetic media at standardized conditions before analysis. The average folate content for these yeast strains was 10,780±550 μg/100 g dry matter. In all yeast strains tested, the most abundant folate forms as percentages were 5-methyltetrahydrofolate (43–59%), and 5-formyltetrahydrofolate (23–38%), whereas tetrahydrafolate occurred in a lesser proportion (19–23%).     

Highly sensitive In0.53Ga0.47As/InP Hallsensors grown by MOVPE

High performance InP/InGaAs Hall sensors appropriate for applications requiring high sensitivity at low power dissipation, good linearity, low temperature sensitivity, and high resolution are reported. The layer structures grown by MOVPE combine a high mobility In _0.53Ga_0.47As channel with isolation by semi-insulating InP. With this design bias current related sensitivities up to 760 V/AT at sheet resistances below 840 Ω/square have been achieved, allowing high output signals at low power dissipation. Due to the active layer isolation by semi-insulating InP, bias currents are not limited by channel pinch-off or junction breakdown. This leads to absolute sensitivities as high as 12.5 V/T. Linearity errors are lower than -0.8% up to magnetic fields of 0.5 T. Temperature coefficients of the sensitivity were measured for different donor concentrations of the active layer. The lowest value of -0.07%/K was found for a doping of 10 ¹⁶ cm^-3, in accordance with theoretical predictions. High signal-to-noise ratios corresponding to minimal detectable fields of 50 nT/Hz^l/2 and 160 nT/Hz^l/2, respectively, were measured at 1 kHz and 100 Hz     

Optical bandwidth and fabrication tolerances of multimodeinterference couplers

Analytical expressions are derived which relate the optical bandwidth and the fabrication tolerances of multimode interference (MMI) couplers to their most important design parameters. These expressions compare adequately with mode analysis simulations. For strong guided structures, the optical bandwidth is shown to he inversely proportional to the number of input and output ports N and to the length of the device. The fabrication tolerances are independent of N and proportional to the output channel separation D. Measurements on MMI couplers in InP/InGaAsP corroborate the theoretical predictions     

A two-stage heuristic method for balancing mixed-model assembly lines with parallel workstations

This work presents a new mathematical programming model for the mixed-model assembly line balancing problem with parallel workstations and zoning constraints. It allows the user to control the process to create parallel workstations. The model's primary goal is to minimize the number of workstations along the line, for a given cycle time, and its secondary goal is to balance the workloads between and within workstations. A two-stage procedure, using a simulated annealing approach, was developed to tackle this complex problem. The first stage of the procedure looks for a sub-optimal solution to the problem's primary goal, whilst the second stage deals with the secondary goal. The procedure is illustrated with a numerical example and the results from computational experiments show that even for large-scale problems the proposed procedure performs very well.     

Unsteady aspects of sodium–water–air reaction

One important issue for the Sodium Fast Reactor (SFR) concept is the reactivity of metallic sodium and its exothermal reaction with water. In particular during equipments washing operations, sodium needs to be firstly converted (‘destroyed’) into non reactive species via a chemical reaction with water. Today, such operations are performed in tanks that confine the system and mitigate the consequences of any possible abnormal condition.     

Transient dynamic analysis of a fluid-saturated porous gradient elastic column

The dynamic response of a fluid-saturated porous gradient elastic column to a transient disturbance is determined analytically and numerically. The basic dynamic theory of a fluid-saturated poroelastic medium due to Biot is modified by replacing the classical linear elastic model of the solid skeleton by the simple gradient elastic model of Mindlin with just one elastic constant (internal length scale) in addition to the classical ones. Thus, the new theory, which is presently restricted to the one-dimensional case, can take into account the microstructural effects of the solid skeleton. After the establishment of appropriate boundary and initial conditions, the one-dimensional dynamic column problem is solved analytically with the aid of the Laplace transform with respect to time. The time domain response is finally obtained by a numerical inversion of the transformed solution. The effect of the solid microstructure on the response is assessed and discussed.