Vitamin D Deficiency in Testicular Cancer Survivors: A Systematic Review

Testicular cancer (TC) is the most frequent tumor in young males. In the vast majority of cases, it is a curable disease; therefore, very often patients experience a long survival, also due to their young age at diagnosis. In the last decades, the role of the vitamin D deficiency related to orchiectomy has become an increasingly debated topic. Indeed, vitamin D is essential in bone metabolism and many other metabolic pathways, so its deficiency could lead to various metabolic disorders especially in long-term TC survivors. In our article, we report data from studies that evaluated the incidence of hypovitaminosis D in TC survivors compared with cohorts of healthy peers and we discuss molecular mechanisms and clinical implications.     

From cassava to gari: mapping of quality characteristics and end-user preferences in Cameroon and Nigeria

User’s preferences of cassava and cassava products along the value chain are supported by specific root quality characteristics that can be linked to root traits. Therefore, providing an evidence base of user preferred characteristics along the value chain can help in the functional choice of cassava varieties. In this respect, the present paper presents the results from focus group discussions and individual interviews on user preferred quality characteristics of raw cassava roots and the derived product, gari, – one of the major cassava products in Sub-Saharan Africa – in major production and consumption areas of Cameroon and Nigeria. Choice of cassava varieties for farming is mainly determined by the multiple end uses of the roots, their agricultural yield and the processing determinants of roots that support their major high-quality characteristics: size, density, low water content, maturity, colour and safety. Processing of cassava roots into gari goes through different technological variants leading to a gari whose high-quality characteristics are dryness, colour, shiny/attractive appearance, uniform granules and taste. Eba, the major consumption form of gari in Cameroon and Nigeria, is mainly characterised by its textural properties: smoothness, firmness, stickiness, elasticity and mouldability. Recommendations are made, suggesting that breeding will have to start evaluating cassava clones for brightness/shininess, as well as textural properties such as mouldability and elasticity of cassava food products, for the purpose of supporting decision-making by breeders and the development of high-throughput selection methods of cassava varieties. Women are identified as important beneficiaries of such initiatives giving their disadvantaged position and their prominent role in cassava processing and marketing of gari.     

Intermediates and isomers in the substitution of cobalt carbonyl hydride with tertiary phosphorous ligands

Mono- and disubstitution of HCo(CO)₄ with tertiary phosphines and phosphites was studied by IR and¹H-NMR spectroscopy. It was found that these substitutions proceed through phosphonium tetracarbonylcobaltate intermediates, leading to a mixture of isomers. The crystal and molecular structure of trans-HCo(CO)₃[P(O-p-C₆H₄Ph)₃] was determined by X-ray diffraction.GDR research fellow at the University of Veszprém.     

Reversible client/server interactions

In the setting of session behaviours, we study an extension of the concept of compliance when a disciplined form of backtracking and of output skipping is present. After adding checkpoints to the syntax of session behaviours, we formalise the operational semantics via an LTS, and define natural notions of checkpoint compliance and sub-behaviour, which we prove to be both decidable. Then we extend the operational semantics with skips and we show the decidability of the obtained compliance.     

Photo‐crosslinked poly(ethylene glycol) diacrylate (PEGDA) hydrogels from low molecular weight prepolymer: Swelling and permeation studies

The aim of this work was to assess the diffusive properties of poly(ethylene glycol) diacrylate (PEGDA)‐based hydrogels, derived from low MW prepolymers, in view of potential biomedical applications. Several hydrogels were synthesized through UV irradiation of PEGDA solutions for different exposure times. Swelling measurements in distilled water were performed to estimate the yielded crosslink density, while swelling tests at 37 °C in selected media allowed to analyze the mesh size changes induced by various pH and ionic strength (IonS) conditions. The transport of glucose and insulin through thin hydrogel membranes was finally assessed in a modified Ussing chamber at physiological values of pH and IonS (7.4 and 150 mM, respectively). Results showed that the swelling was dependent on the IonS (with swelling reductions up to 20–30% for IonS increases in the range 0–300 mM) and, to a lesser extent, on the pH of the surrounding medium (with swelling increments of about 10% for increasing pH in the range 2.5–11). All hydrogels were also permeable to glucose and insulin, which displayed comparable diffusion coefficients (in the order of 10^?6 cm²/s). Specific interactions between glucose and the polymer chains were evidenced by values of the partition coefficient higher than unity. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 44380.     

Building a geodatabase for mapping hydrogeological features and 3D modeling of groundwater systems: Application to the Saguenay-Lac-St.-Jean region, Canada

Understanding and managing groundwater resources require the integration of a large amount of high-quality data from a variety of sources. Due to the limitations in accessing information related to groundwater and subsurface conditions, the gathering of available existing information is of crucial importance when conducting a successful hydrogeological study. Here, we present an approach for the development of an exhaustive and comprehensive groundwater database through (1) the gathering of relevant sources of information relating to groundwater, and (2) the application of a quality control process in order to screen the data for accuracy and quality. This hydrogeological database is then implemented within a GIS (geographic information system) framework coupled to a Relational Database Management System (RDBMS) as a personal geodatabase (ESRI format) GIS technology. Once established, the spatial database allows a user to request the relevant data required for a specific hydrogeological study. In addition, stratigraphic data stored within the spatial database may be utilized for constructing 3D subsurface hydrostructural models. In order to achieve this objective, the software Arc Hydro Groundwater combined with the ArcGIS spatial database is shown to be appropriate for the 3D structural representation of aquifers (groundwater reservoirs). The innovative contribution of this approach in building 3D hydrostructural subsurface models from a spatial database resides in simplifying the required step-by-step processes by considering a unified compatible combination of “RDBMS-ArcGIS-Arc Hydro Groundwater” technologies. The proposed methodology is illustrated using data from an ongoing project aimed at developing an inventory of the groundwater resources of the Saguenay-Lac-Saint-Jean region, Quebec (Canada).     

Sub-Finsler Structures from the Time-Optimal Control Viewpoint for some Nilpotent Distributions

In this paper, we study the sub-Finsler geometry as a time-optimal control problem. In particular, we consider non-smooth and non-strictly convex sub-Finsler structures associated with the Heisenberg, Grushin, and Martinet distributions. Motivated by problems in geometric group theory, we characterize extremal curves, discuss their optimality, and calculate the metric spheres, proving their Euclidean rectifiability.     

Exploring the effectiveness of an augmented reality dressing room

Multimedia Tools and Applications - In this paper, we describe our experience with the design of an augmented reality dressing room in which 3D models of a dress are overlaid with a color image...