An integrated semantic framework supporting universal accessibility to ICT

As we are moving rapidly to a digital economy, accessing and effectively using Information and Communication Technologies (ICT) in everyday life is widely recognized as an important requirement. However, the accessibility technologies that we have up to date are meeting the needs of only some, at a very high cost and, as a consequence, accessible ICT for all people still remains a major research and development goal. This work presents an integrated ontological framework for the semantic representation of terms and concepts (i.e., related to user needs and preferences (N&P) with respect to ICT use, as well as solutions, platforms and devices) that are required for addressing the universal accessibility in the scope of the Cloud4all project and the Global Public Inclusive Infrastructure (GPII). Cloud4all aims at advancing and building upon the concept of GPII through the development of the necessary tools and models for making ICT accessible for all by exploiting the cloud computing paradigm. The main goal of the proposed framework lays in the separation between generalized accessibility concepts, user interaction mechanisms and N&P with the particular details of different ICT artifacts. Thus, the framework aims at integrating concepts related with user N&P, as well as ICT solutions, platforms, devices and their customizable settings along with information concerning their vendors or implementers, in order to (a) offer the necessary expressiveness for defining/representing personal N&P across applications, platforms and devices, (b) link N&P with the conditions/context according to which these shall be applicable for (e.g., considering the user activity and the physical environment), (c) link interaction requirements (originated from user characteristics) with N&P and (d) support the Cloud4all matchmaking process through the mapping between N&P and application-specific settings based on semantic rules and automatic reasoning techniques.     

The Granger-causality between income and educational inequality: a spatial cross-regressive VAR framework

This paper tests the causal processes between income and educational inequality within regions of the European Union, using a spatial cross-regressive VAR framework. The results show that there is a heterogeneous causality from income inequality to educational inequality and vice versa, and interregional income and educational externalities are relevant to this causality. This finding raises potentially interesting economic policy implications.     

Energy‐aware traffic allocation to optical lightpaths in multilayer core networks

The amount of traffic that is generated by users and high‐demanding services is expected to rise dramatically in the forthcoming years. This will unavoidably deteriorate the performance and increase the consumed energy of core networks, thus constraining the growth of Internet. To this effect, multilayer traffic engineering schemes in IP/multiprotocol label switching over dense wavelength division multiplexing networks have been proposed for achieving improved performance and increased energy savings by flexibly allocating traffic to optical lightpaths. In particular, the consumed energy in a router can be minimized if the lightpaths are established so as to traverse a router without electronic processing and conversion of their signal between optical and electrical layer. Accordingly, this paper aims at providing an energy‐aware solution to the problem of traffic allocation to optical lightpaths in multilayer core networks. The problem is first formulated and then a solution based on a heuristic algorithm, called energy‐aware traffic allocation to optical lightpaths (ETAL) is proposed. The efficiency and worthiness of ETAL is validated through numerous scenarios and simulations. The derived results indicate that the proposed algorithm is an efficient traffic engineering solution that exhibits better performance in terms of consumed energy (up to 44%), when compared to other similar traffic allocation schemes. Copyright © 2015 John Wiley & Sons, Ltd.     

Physical evaluation of a maize‐based extruded snack with curry powder

Response surface methodology was used to analyze the effect of screw speed (200–280 rpm), feed moisture (13.0–17.0%, wet basis), and curry powder (6.0–9.0%) on the bulk density, lateral expansion, and firmness of maize‐based extruded snack with curry powder. Regression equations describing the effect of each variable on the responses were obtained. Responses were most affected by changes in feed moisture followed by screw speed and curry powder (p < 0.05). Lateral expansion increased linearly as the amount of curry powder added was increased whereas a quadratic increase was obtained in lateral expansion with decreasing feed moisture. The firmness of samples was increased with an increase in feed moisture. The bulk density of samples was increased with increasing feed moisture and screw speeds. Radial expansion was found to be a better index to measure the physical properties of the extruded product indicated by a higher correlation coefficient.     

KnowBaSICS-M: an ontology-based system for semantic management of medical problems and computerised algorithmic solutions

In this paper, an ontology-based system (KnowBaSICS-M) is presented for the semantic management of Medical Computational Problems (MCPs), i.e., medical problems and computerised algorithmic solutions. The system provides an open environment, which: (1) allows clinicians and researchers to retrieve potential algorithmic solutions pertinent to a medical problem and (2) enables incorporation of new MCPs into its underlying Knowledge Base (KB). KnowBaSICS-M is a modular system for MCP acquisition and discovery that relies on an innovative ontology-based model incorporating concepts from the Unified Medical Language System (UMLS). Information retrieval (IR) is based on an ontology-based Vector Space Model (VSM) that estimates the similarity among user-defined MCP search criteria and registered MCP solutions in the KB. The results of a preliminary evaluation and specific examples of use are presented to illustrate the benefits of the system. KnowBaSICS-M constitutes an approach towards the construction of an integrated and manageable MCP repository for the biomedical research community.     

Supporting Temporal Views in a Management Information Base

In many network management applications, likepost-mortem fault analysis or performance trendsprofiling, it is advantageous to have the ability toview the state of the network as it was at some time in the past. To support such Temporal Views anefficient data organization, or access method, is neededfor storing and updating network related data (as thenetwork evolves over time) and for retrieving requested past network states. For applications where thenetwork manager is not interested in the full (and maybetoo large) snapshot of a past network state it is usefulif partial state snapshots can be extracted quickly. It is thus of particular interest toconstruct an access method that can efficiently supportPartial Temporal Views. Efficiency implies that arequested partial temporal view should be constructed directly, without first computing the elaboratefull temporal view. In this paper we present a newaccess method (called the Neighbor History Index) forthis problem. One of the advantages of this method is that the update processing is independent ofthe evolution size (the total number of changes in theevolution). In addition, our method uses a small diskspace overhead. We then present a general framework for organizing time-evolving network data. Ourframework distinguishes between flat and hierarchicalevolutions and subsequently between flat andhierarchical temporal views. We also provide a way toefficiently construct temporal views on hierarchicalevolutions. This paper shows that supporting temporalviews on flat or hierarchical evolutions is notexpensive: our solutions use small space overhead, havesmall updating and compute temporal viewsfast.     

Design of product specifications and control policies in a single-stage production system

Screening (100%-inspection) is a common practice in quality engineering. Traditional screening procedures seek upper and lower specification limits for a quality characteristic associated with some product, such that the total quality cost per item is minimized. This practice ignores the effect of parts rejection on product lead times, inventory carrying costs, shortage costs, throughput, and, eventually, total profit rate of the system. In this paper, a single-stage production system is considered and two control policies arc determined jointly with the inspection plans. Numerical experiments indicate that such co-ordinated policies achieve a better performance than independently determined quality and production control policies     

Finite modeling of parabolic equations using Galerkin methods and inverse matrix approximations

In this paper we examine order reduction of parabolic systems using modal truncation. The parabolic distributed system is first approximated using the Galerkin method. The system matrices have a special structure that allows us to find the approximate spectrum of the parabolic system. To do this we compute approximate inverses of tridiagonal, diagonally dominant symmetric matrices. The approximation leads to algorithms of orderO(n), as opposed to traditional algorithms of orderO(n), wheren is the order of the system. Finally, an example is presented to illustrate the proposed algorithm.This research was supported by the National Science Foundation under contract NCR-9210408, by the Advanced Research Programs Agency under contract MDA-972-93-1-0032, and by the University of Hawaii Research Council Funds.     

Directed evolution on the cold adapted properties of TAB5 alkaline phosphatase

Psychrophilic alkaline phosphatase (AP) from the Antarctic strain TAB5 was subjected to directed evolution in order to identify the key residues steering the enzyme's cold-adapted activity and stability. A round of random mutagenesis and further recombination yielded three thermostable and six thermolabile variants of the TAB5 AP. All of the isolated variants were characterised by their residual activity after heat treatment, Michaelis-Menten kinetics, activation energy and microcalorimetric parameters of unfolding. In addition, they were modelled into the structure of the TAB5 AP. Mutations which affected the cold-adapted properties of the enzyme were all located close to the active site. The destabilised variants H135E and H135E/G149D had 2- and 3-fold higher kcat, respectively, than the wild-type enzyme. Wild-type AP has a complex heat-induced unfolding pattern while the mutated enzymes loose local unfolding transitions and have large shifts of the Tm values. Comparison of the wild-type and mutated TAB5 APs demonstrates that there is a delicate balance between the enzyme activity and stability and that it is possible to improve the activity and thermostability simultaneously as demonstrated in the case of the H135E/G149D variant compared to H135E.     

Spectroscopic investigations on the depth-dependent degradation gradients of aged triterpenoid varnishes

The depth-profiles of accelerated aged triterpenoid dammar and mastic varnishes, which had been uncovered by optimized KrF excimer laser ablation (248 nm, 25 ns), were examined by ultraviolet-visible (UV/VIS) spectrophotometry and attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectroscopy. The results reflect both the optical properties at the bulk (UV/VIS) and the surface (ATR/FT-IR) and establish the presence of degradation gradients across the depth of the degraded natural resin films. It is demonstrated that the UV part of the ambient radiation is absorbed by the deteriorated surface and that the optical densities of the aged varnish decrease as a function of depth. The absorbed UV wavelengths at the surface and the depth-wise reduction of light intensity result in a depth-dependent decrease in carbonyl absorbance and an increase in C-H bending vibration modes of methylene species pointing to structural modification in the triterpenoid mixture across depth.