Sulfhydryl phosphorus-containing collectors in flotation of copper–nickel platinum-group metals

The analysis involves influence of sulfhydryl phosphorus-containing collectors (SPC) on flotation of copper–nickel ore-bearing metals from platinum group. Efficiency of SPC and butyl xanthate combination is illustrated, and their optimal ratio is determined. The authors study influence of the test agents on electrode potential and hydrophobic behavior of pyrrhotine, pentlandite and platinum black. UV and IR spectrophotometry has shown origination of disulfide di-isobutyl dithiophosphinate on the surface of pyrrhotine.     

Choice of line reactors for HVDC lines and back-to-back links

Recommendations on the choice of a line reactor for HVDC lines and back-to-back links have been systematized. It is shown how the HVDC self-resonant frequencies should be detuned from resonance with network harmonics and how long-standing operation of BTBL and HVDC should be provided in commutations, failures, lightning high voltages, and short-circuit current.     

Study of the Consolidation and Phase Formation in the γ-TiAl-Based Material Sintered with a TiH2 Precursor

Powder Metallurgy and Metal Ceramics - The hydride powder technique was employed to produce intermetallic TiAl alloys using a mixture of Al and TiH2 powders. The features peculiar to the...     

Genome-Wide Association Analysis and Genomic Prediction of Thyroglobulin Plasma Levels

Thyroglobulin (Tg) is an iodoglycoprotein produced by thyroid follicular cells which acts as an essential substrate for thyroid hormone synthesis. To date, only one genome-wide association study (GWAS) of plasma Tg levels has been performed by our research group. Utilizing recent advancements in computation and modeling, we apply a Bayesian approach to the probabilistic inference of the genetic architecture of Tg. We fitted a Bayesian sparse linear mixed model (BSLMM) and a frequentist linear mixed model (LMM) of 7,289,083 variants in 1096 healthy European-ancestry participants of the Croatian Biobank. Meta-analysis with two independent cohorts (total n = 2109) identified 83 genome-wide significant single nucleotide polymorphisms (SNPs) within the ST6GAL1 gene (p<5×10−8). BSLMM revealed additional association signals on chromosomes 1, 8, 10, and 14. For ST6GAL1 and the newly uncovered genes, we provide physiological and pathophysiological explanations of how their expression could be associated with variations in plasma Tg levels. We found that the SNP-heritability of Tg is 17% and that 52% of this variation is due to a small number of 16 variants that have a major effect on Tg levels. Our results suggest that the genetic architecture of plasma Tg is not polygenic, but influenced by a few genes with major effects.