Unusual Two-Step Assembly of a Minimalistic Dipeptide-Based Functional Hypergelator

Self-assembled peptide hydrogels represent the realization of peptide nanotechnology into biomedical products. There is a continuous quest to identify the simplest building blocks and optimize their critical gelation concentration (CGC). Herein, a minimalistic, de novo dipeptide, Fmoc-Lys(Fmoc)-Asp, as an hydrogelator with the lowest CGC ever reported, almost fourfold lower as compared to that of a large hexadecapeptide previously described, is reported. The dipeptide self-assembles through an unusual and unprecedented two-step process as elucidated by solid-state NMR and molecular dynamics simulation. The hydrogel is cytocompatible and supports 2D/3D cell growth. Conductive composite gels composed of Fmoc-Lys(Fmoc)-Asp and a conductive polymer exhibit excellent DNA binding. Fmoc-Lys(Fmoc)-Asp exhibits the lowest CGC and highest mechanical properties when compared to a library of dipeptide analogues, thus validating the uniqueness of the molecular design which confers useful properties for various potential applications.     

核电厂中间量程保护定值标定方法改进

基于目前中国改进型三环路压水堆（CPR1000）部分机组存在因中间量程电流饱和导致无法在48%额定功率（Pn）完成定值标定及核电厂大修经济性考虑，采用MCNP程序及核设计软件包SCIENCE，研究分析中间量程保护定值标定的新方法。分析结果表明，中间量程保护定值标定调整至30%Pn功率平台实施，采用改进方法标定的保护定值更接近于设计值。      

Improving the initialization speed for long-range NRTK in network solution mode

Initialization speed is one of the most important factors in network real time kinematic (NRTK) performance. Owing to the low correlation among the error s     

冷矫机弯辊控制的完善与优化研究

本文据国内矫直机的使用情况,提出完善弯辊功能,解决辊缝标定清零及运行中的问题,提升轧钢厂运行效率与产品质量。     

基于Cortex-M的嵌入式设备固件更新方法研究

本文提出了一种基于分散加载技术实现Boot程序和用户应用程序在同一个工程编写开发的固件更新方法 .通过编写分散加载规范文件在工程中实现代码存储区分区.为了保证固件更新的稳定性和可靠性,在固件下载过程中引入CRC校验、丢包错包重传等容错技术.实验结果 验证了方法的有效性和可靠性.