酶法钝化大豆中胰蛋白酶抑制因子的研究

采用国家标准GB 21498—2008检测钝化后大豆中胰蛋白酶抑制因子的活性。四因素四水平正交试验设计结果表明,最优的钝化工艺条件为：温度为45℃、pH 3.5、酸性蛋白酶用量为0.005μL/g、底物浓度为4%,在此条件下钝化完全,抑制率达97.8%。     

基于颜色矢量角的彩色图像检索算法研究

通过分析利用颜色直方图进行图像检索时存在的问题,提出了一种基于图像边缘空间分布特征的图像检索算法.即利用颜色矢量角对亮度不敏感,对色度和饱和度敏感的特性来提取图像的边缘信息.在图像的边缘空间,提取图像边缘点的颜色矢量角直方图,以此来描述图像的内容.该算法充分利用了图像的颜色信息、边缘信息及形状信息,实验表明该算法具有较好的光照不变性、尺度不变性、平移不变性和旋转不变性.     

PWM电液比例放大器的研制

本文讨论用单片机构成PWM电液比例放大器的硬件和软件设计。该放大器能寻优PWM的频率,能补偿校正比例电磁铁固有的滞回,能输出多种时间——电流波形,对流过电磁铁的电流进行PID闭环控制。具有结构简单、调试方便、功耗小、成本低廉的优点。     

基于GSM模块的电力变压器防盗系统

文章主要介绍了由单片机和GSM短信模块（TC35）组成的防盗系统,借助最可靠、最成熟的GSM移动网络,以短消息或电话形式,直接将报警地点的情况通过GSM网络与您的手机24小时保持联系。采用热释红外传感器和电感式接近开关对变压器进行监视,将传统的有线防盗系统变为无线的,给电力变压器的安全加了一个保险。     

南淝河生态补水水质改善效应试验研究

为改善南淝河水体水质,利用南淝河流域水污染治理和水生态修复成果,通过南淝河生态补水试验率定和验证 MIKE11 水动力水质模型合理性,分析南淝河在不同生态补水量下水质变化。MIKE11 水动力水质模型能够较好地模拟南淝河在生态补水条件下水动力和水环境质量改善的情况。通过条件优化和试算得出,与入河污染物总量相比,生态补水后河道自净能力的贡献占比约 14.6%～19.0%,其中河道自净能力增量占比约 6.2%～9.4%。研究结果表明,生态补水对南淝河水体水质情况有所改善,但仍以稀释作用为主,河道自净能力发挥的作用有限。     

Intranasal Administration of Codium fragile Polysaccharide Elicits Anti-Cancer Immunity against Lewis Lung Carcinoma

Natural polysaccharides have shown promising effects on the regulation of immunity in animals. In this study, we examined the immune stimulatory effect of intranasally administered Codium fragile polysaccharides (CFPs) in mice. Intranasal administration of CFPs in C57BL/6 mice induced the upregulation of surface activation marker expression in macrophages and dendritic cells (DCs) in the mediastinal lymph node (mLN) and the production of interleukin-6 (IL-6), IL-12p70, and tumor necrosis factor-α in bronchoalveolar lavage fluid. Moreover, the number of conventional DCs (cDCs) was increased in the mLNs by the upregulation of C-C motif chemokine receptor 7 expression, and subsets of cDCs were also activated following the intranasal administration of CFP. In addition, the intranasal administration of CFPs promoted the activation of natural killer (NK) and T cells in the mLNs, which produce pro-inflammatory cytokines and cytotoxic mediators. Finally, daily administration of CFPs inhibited the infiltration of Lewis lung carcinoma cells into the lungs, and the preventive effect of CFPs on tumor growth required NK and CD8 T cells. Furthermore, CFPs combined with anti-programmed cell death-ligand 1 (PD-L1) antibody (Ab) improved the therapeutic effect of anti-PD-L1 Ab against lung cancer. Therefore, these data demonstrated that the intranasal administration of CFP induced mucosal immunity against lung cancer.     

Prefrontal cortical projections to the hypothalamus in macaque monkeys

The organization of projections from the macaque orbital and medial prefrontal cortex (OMPFC) to the hypothalamus and related regions of the diencephalon and midbrain was studied with retrograde and anterograde tracing techniques. Almost all of the prefrontal cortical projections to the hypothalamus arise from areas within the "medial prefrontal network," as defined previously by Carmichael and Price ([1996] J. Comp. Neurol. 371:179-207). Outside of the OMPFC, only a few neurons in the temporal pole, anterior cingulate and insular cortex project to the hypothalamus. Axons from the OMPFC also innervate the basal forebrain, zona incerta, and ventral midbrain. Within the medial prefrontal network, different regions project to distinct parts of the hypothalamus. The medial wall areas 25 and 32 send the heaviest projections to the hypothalamus; axons from these areas are especially concentrated in the anterior hypothalamic area and the ventromedial hypothalamic nucleus. Orbital areas 13a, 12o, and Iai, which are related to the medial prefrontal network, selectively innervate the lateral hypothalamic area, especially its posterior part. The cellular regions of the paraventricular, supraoptic, suprachiasmatic, arcuate, and mammillary nuclei are conspicuously devoid of cortical axons, but many axons abut the borders of these nuclei and may contact dendrites that extend from them. Areas within the orbital prefrontal network on the posterior orbital surface and agranular insula send only weak projections to the posterior lateral hypothalamic area. The rostral orbital surface does not contribute to the cortico-hypothalamic projection.     

用于微流控荧光PCR的高分辨率温度控制系统

微流控荧光PCR产物在高分辨率熔解（HRM）曲线分析的过程中,随着DNA的解链荧光强度发生突变,而能否检测到该突变点则依赖于温控的精度。提出了多阈值PID算法,设计了一种适用于高分辨率熔解曲线分析的FPGA温度控制系统。根据测得温度值与设定值之间的差异,改变FPGA电路系统输出的脉冲宽度调制(pulse width modulation, PWM)波占空比和算法的调节频率实现对温度的准确控制。经过温度标定后,系统温度控制精度优于0.1℃,分辨率达到±0.01℃。HRM分析实验结果表明,本方法成功地辨别出了DNA序列的单碱基差异,温度控制系统达到了设计的要求。     

强筋小麦磨制面包粉工艺研究

为了研究中国育成并大面积推广强筋小麦品种的面包粉制粉工艺,以中国第一批确定的强筋面包小麦品种陕优225为主要原料,以国产4皮3芯中型加工设备进行工艺研究,同时也进行了以陕优225小麦为主原料的配麦试验。结果表明,面粉蛋白质品质,即蛋白质含量、湿面筋含量均以皮磨高于芯磨,皮磨由1B到4B逐渐升高,芯磨则由1M到3M逐渐降低;面团流变学品质除吸水率外,形成时间、稳定时间、拉伸性均与蛋白质品质规律基本一致,所不同的是面团流变学品质以3B为最高;面包烘焙品质面包体积和面包总评分其规律性与面团流变学品质相一致,皮磨以3B皮最好,以1B最差,芯磨以1M最好,3M最差。配麦试验结果显示,以陕优225与另一形成时间长的强力面包小麦以85:15配麦,取2B、3B、4B、1M、2M、3M前路粉,依次配置筛目目数为100、120、130、100、120目和130目,面粉品质明显改善,面包烘焙评分提高5.0～8.8分。