Coding combinatorial sources with costs

We consider coding infinite sequences of a finite alphabet. The source is defined as a set of sequences (combinatorial source). The problem is to minimize the worst asymptotic compression ratio between each sequence and its coding output among the sequences in the combinatorial source. Ryabko showed that the optimal value coincides with the Hausdorff dimension of the combinatorial source. This correspondence extends the previous work in that the input and output costs are expressed in terms of not lengths but generalized costs. The essential quantity turns out to be the Hausdorff dimension with respect to the measure associated with the input cost. We construct an asymptotically optimal coding procedure, and also show that no coding scheme can beat the lower bound.     

Threshold for Millimeter-Wave (60 GHz)-Induced Ocular Injury

Journal of Infrared, Millimeter, and Terahertz Waves - Millimeter waves (MMW) absorbed by skin or cornea may induce damage by heat. We have developed a 60 GHz MMW exposure-induced eye...     

Engineering of Lipid Nanoparticles by the Multifunctionalization of the Surface with Amino Acid Derivatives for the Neutralization of a Target Toxic Peptide

Protein affinity reagents (e.g., antibodies) are often used for basic research, diagnostics, separations, and disease therapy. Although a lot of “synthetic” protein affinity reagents have been developed as a cost-effective alternative to antibodies, their low biocompatibility is a considerable problem for clinical application. Lipid nanoparticles (LNP) represent a highly biocompatible drug delivery agent. However, little has been reported that LNP itself works as a protein affinity reagent in living animals. Here, LNP is engineered for binding to and neutralizing a target toxic peptide in living animals by multifunctionalization with amino acid derivatives. Multifunctionalized LNP (MF-LNP) is prepared using amino acid derivative-conjugated lipids. Optimized MF-LNP exhibits nanomolar affinity to the target toxic peptide and inhibits toxic peptide-dependent hemolysis and cytotoxicity. In addition, MF-LNP captures and neutralizes the toxic peptide after intravenous injection in the bloodstream; in addition, MF-LNP does not release the toxic peptide in the accumulated organ. These results reveal the potential of using LNP as a highly biocompatible protein affinity reagent such as an antidote.     

Block Copolymer Permeable Membrane with Visualized High‐Density Straight Channels of Poly(ethylene oxide)

A simple fabrication, scalable to centimeter scale, of a permeable membrane made of block copolymer containing molecular transport channels is demonstrated by coating photo‐crosslinkable liquid‐crystalline block copolymer, consisting of poly(ethylene oxide) (PEO) and poly(methacrylate) (PMA) bearing stilbene (Stb) mesogens in the side chains (PEO₁₁₄‐b‐PMA(Stb)₅₂), onto a sacrificial cellulose acetate film substrate. After thermal annealing, perpendicularly aligned and hexagonally arranged PEO cylindrical domains with a surface density of 10¹¹ cm^?2 were formed and then fixed efficiently by photo‐crosslinking the stilbene moieties in the PMA(Stb) domains by [2 + 2] dimerization. The fully penetrating straight PEO cylindrical domains across the 480‐nm‐thick membrane were well‐defined and visualized as molecule‐transport channels. After exfoliated by removal of the cellulose acetate layer, the membrane could be transferred onto another substrate by either scooping or a horizontal lifting method. Throughout the processes, the fully penetrating PEO channels across the membrane are preserved to open at both ends. A simple permeation experiment demonstrates that rhodamine dyes permeate efficiently through the PEO cylindrical channels of the annealed membrane but not across a non‐annealed one.     

A Terahertz Video Camera Patch Sheet with an Adjustable Design based on Self-Aligned, 2D,Suspended Sensor Array Patterning

Terahertz (THz) imaging is expected to become powerful tools for non-destructive inspections. To ensure the practical use of THz non-destructive monitoring, versatile THz imagers with adjustable designs that can eliminate the complexities and the bulkiness of the device are urgently required. Herein, a self-aligned filtration process for a 2D, free-standing carbon nanotube film array and its application to a THz video camera patch are reported. The presented techniques enable a) to freely design the camera size, sensor array pattern, and suspended shape according to its applications, b) to cut the camera patch into desired shapes, and c) to attach them to the objects that are intended to be measured. Real-time, non-destructive monitoring of various infrastructures is demonstrated. These results indicate that it can function regardless of restrictions, such as the shapes and locations of the measurement samples, thus providing a strong possibility for use in future non-destructive sensor networks.     

Analysis of photoreceptor membrane turnover in a Drosophila visual mutant, rdgA, by electron microscope autoradiography

A Drosophila visual mutant, rdgA, has photoreceptor cells whose rhabdomeres degenerate in several days after eclosion. Incorporations of 3H-amino acids, and 3H-mannose and 3H-glucosamine residues into the photoreceptive membranes were studied in newly emerged rdgA mutant flies by electron microscope autoradiography. The amount of 3H-amino acids incorporated in rdgA rhabdomeres at 3 hr after the injection was about 50%, and that of 3H-sugar residues was about 20% of normal. Together with our previous finding that degradative activity is low in rdgA cell bodies at this time, these data indicate that the supply of photoreceptive membrane proteins is defective in rdgA.     

A sub-0.5-V operating embedded SRAM featuring a multi-bit-error-immune hidden-ECC scheme

The mobile multi-media applications require to lower the operating voltage of embedded SRAMs. The ECC circuit implementation for increasing soft-error and the access timing control that tracks access delay fluctuation in memory core should be considered for the low-voltage operation. A hidden error-check-and-correction (HECC) scheme compensated the access time penalty caused by the ECC logic on the output critical path. And a multi-column ECC word assignment (MCE) increased the multi-bit-error immunity while using only 1-bit-correctable ECC which minimized area penalty. A source-level-adjusted direct sense amplifier (SLAD) and a write-replica circuit with an asymmetrical replica memory cell (WRAM) for the device-fluctuation-tolerant access control were also designed. A 130-nm CMOS 32-Kbit SRAM-macro was fabricated with these circuit techniques, which demonstrated: 1) 0.3-V operation with 6.8 MHz; 2) 30-MHz operation which is feasible for mobile use even at 0.4 V, while keeping 960MHz at 1.5 V; and 3) a reduction by 3.6/spl times/10/sup 5/ in soft-error rate compared with that of conventional ECC.     

Correlation study between VAD preform deposition surface and Germanium doping profiles

The refractive index profile of germanium doped preforms for optical fibers is determined by the radial distribution of germanium concentration. Knowing that there is a correlation between the germanium doping profile and the deposition surface profile of vapor-phase axial deposition (VAD) preforms, the study of this correlation has been carried out in order to estimate, indirectly, the refractive index profile of VAD preforms for optical fibers during the deposition stage. This correlation was studied through the parameterization of the preform deposition surface using two parameters: the power law index profile that best fits the preform bottom profile (/spl alpha/) and the axial distance from the bottom tip to a reference height (h). A range of values of these parameters to produce VAD preforms with standard and special doping profiles has been presented. Preforms with triangular index profile can be fabricated with /spl alpha/ and h values of about 2.0 and 5.0 mm, respectively, and preforms with parabolic index profiles can be produced with /spl alpha/ and h values of about 2.0 and 4.0 mm, respectively.     

Thermoelectric Generation Using Water Lenses

A solar light concentrator composed of water and plastic transparent film has been designed. This flexible lens design can trace the solar movement through control of the tensile stress and amount of water, and concentrate the solar energy onto the thermoelectric (TE) module surface. An experimental water lens was constructed, and the concentrated intensity was monitored by a photodiode as a function of x–z position; For example, when 3.0 kg water was filled and tension of 69.0 N/m was applied to the transparent vinyl sheet, the concentration ratio was evaluated as the maximum of 28.0 at a depth of 657 mm from the water lens bottom surface. TE generation was tested to show the validity of the water lens. The surface condition of the receiver was found to be critical.     

Ocular Effects of Exposure to 40, 75, and 95 GHz Millimeter Waves

The objective of this study was to develop a model of ocular damage induced by 40, 75, and 95 GHz continuous millimeter waves (MMW), thereby allowing assessment of the clinical course of ocular damage resulting from exposure to thermal damage-inducing MMW. This study also examined the dependence of ocular damage on incident power density. Pigmented rabbit eyes were exposed to 40, 75, and 95 GHz MMW from a spot-focus-type lens antenna. Slight ocular damage was observed 10 min after MMW exposure, including reduced cornea thickness and reduced transparency. Diffuse fluorescein staining around the pupillary area indicated corneal epithelial injury. Slit-lamp examination 1 day after MMW exposure revealed a round area of opacity, accompanied by fluorescence staining, in the central pupillary zone. Corneal edema, indicative of corneal stromal damage, peaked 1 day after MMW exposure, with thickness gradually subsiding to normal. Three days after exposure, ocular conditions had almost normalized, though corneal thickness was slightly greater than that before exposure. The 50% probability of ocular damage (DD₅₀) was in the order 40?>?95?≈?75 GHz at the same incident power densities.