Miscibility of poly(acrylic acid)/poly(methyl vinyl ketone) blend and in vitro application as drug carrier system

A series of poly(acrylic acid)/poly(methyl vinyl ketone) (PAA/PMVK) blends with different compositions were prepared by the solvent casting method. The miscibility of this pair of polymers was investigated by differential scanning calorimetry(DSC), Fourier transform infra-red (FTIR) and X-Ray diffraction (XRD) techniques. An in-vitro cytotoxicity test of the drug-carrier system via MTT (3-(4,5-demethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay revealed no significant cytotoxic effects at concentrations up to 100 µg· ml^?1. The STX/PAA-50 drug carrier systems were also prepared by solvent casting of solutions containing the sulfamethoxazole (STX) used as drug model and PAA/PMVK blend in N.N-dimethylformamide then crosslinked with acidified ethylene glycol. The release dynamic of STX from the prepared hydrogels was investigated in which the diffusion through the polymer matrix, the enhancement of the water solubility of STX, the influence of the initial drug concentration, the pH of the medium, and the effect of the degree of swelling of the polymer matrix on the release dynamic was evaluated. According to the total gastrointestinal transit time estimated by Belzer, the estimate distribution of STX released in the different organs indicated that the performance is obtained with the drug – carrier-system containing equal ratios of polymer and 10 wt% of STX (STX-10/PAA-50).     

Thermal performance of different pond cells under actual climatic conditions in Qatar

Experimental work was undertaken to study the thermal performance of three different pond cells under actual climatic conditions of Qatar. The first cell was an open pond. In the second unit, a finned radiator, painted black, was placed over the pond. In the third cell, the water was contained in a polyethylene bag. Experimental results indicated that the exposed pond cell came out best, when considered in terms of how quickly the temperature of the stored water could be reduced, and how low that temperature could be. The water in the exposed pond was cooled directly (by evaporation and radiation to sky) whereas in the case of the finned radiator cell, heat had to be transferred from the stored water to the radiator, and then from the radiator to the surrounding. In the case of water-in-bag cell, evaporation was eliminated and radiative exchange with the sky was reduced due to the partial transparency of the polyethylene bag (in the infrared region).     

A genetic programming model for bankruptcy prediction: Empirical evidence from Iran

Prediction of corporate bankruptcy is a phenomenon of increasing interest to investors/creditors, borrowing firms, and governments alike. Timely identification of firms’ impending failure is indeed desirable. By this time, several methods have been used for predicting bankruptcy but some of them suffer from underlying shortcomings. In recent years, Genetic Programming (GP) has reached great attention in academic and empirical fields for efficient solving high complex problems. GP is a technique for programming computers by means of natural selection. It is a variant of the genetic algorithm, which is based on the concept of adaptive survival in natural organisms. In this study, we investigated application of GP for bankruptcy prediction modeling. GP was applied to classify 144 bankrupt and non-bankrupt Iranian firms listed in Tehran stock exchange (TSE). Then a multiple discriminant analysis (MDA) was used to benchmarking GP model. Genetic model achieved 94% and 90% accuracy rates in training and holdout samples, respectively; while MDA model achieved only 77% and 73% accuracy rates in training and holdout samples, respectively. McNemar test showed that GP approach outperforms MDA to the problem of corporate bankruptcy prediction.     

Marble mosaic tiling automation with a four degrees of freedom Cartesian robot

The art of mosaic has arisen thousands of years ago. Despite all those years and all the attention it has received till today, mosaic tiling is still being carried out manually and mosaic tiling processes have never been changed except the tool and material developments.     

A High-Frequency Variable-Voltage-Fed Inverter

A half-bridge inverter circuit capable of providing a wide range of ac output voltages and frequencies is presented. The inverter uses asymmetrical thyristors (ASCR's), which have the advantages of high-power handling capability, small turn-on and turn-off times, and exhibit the same ruggedness associated with conventional thyristors in regards to surge current and gating requirements. By using ASCR's for the main and auxiliary devices, the inverter offers other advantages such as low snubber-power loss, low commutation loss, simple protection circuits, and the ability to operate at high frequencies with different types of loads. Output voltage control is obtained by feeding the inverter from a variable dc source. Two fixed-value auxiliary dc sources are used to obtain a constant-current interruption capability. The performance of the inverter is evaluated both analytically and experimentally.     

All-pole biquadratic filter realization with the minimum ripple due to parameter variations

In this work, the minimization of the ripple in the relative change of the transfer function amplitude due to parameter variations is studied for the signal-flow graph of the state equations realizing all-pole second-order transfer function. First the measure for the ripple is defined and then branch transmittances minimizing the measure are found. the results obtained in this study can be used in all-pole active filter realizations with the minimum ripple measure.     

An intelligent system for multivariate statistical process monitoring and diagnosis

A knowledge-based system (KBS) was designed for automated system identification, process monitoring, and diagnosis of sensor faults. The real-time KBS consists of a supervisory system using G2 KBS development software linked with external statistical modules for system identification and sensor fault diagnosis. The various statistical techniques were prototyped in MATLAB, converted to ANSI C code, and linked with the G2 Standard Interface. The KBS automatically performs all operations of data collection, identification, monitoring, and sensor fault diagnosis with little or no input from the user. Navigation throughout the KBS is via menu buttons on each user-accessible screen. Selected process variables are displayed on charts showing the history of the variables over a period of time. Multivariate statistical tests and contribution plots are also shown graphically. The KBS was evaluated using simulation studies with a polymerization reactor through a nonlinear dynamic model. Both normal operation conditions as well as conditions of process disturbances were observed to evaluate the KBS performance. Specific user-defined disturbances were added to the simulation, and the KBS correctly diagnosed both process and sensor faults when present.     

Bacteriophages isolated from activated sludge processes and their polyvalency

In this study, bacteriophages were isolated from activated sludge and their host range was studied. Bacterial isolates were obtained from an activated sludge process treating urban sewage, and bacteriophages were obtained by plaque assay using the bacterial isolates obtained in this study as the host. Out of 15 bacteria isolated, 9 supported plaque formation. The host range test was conducted with a combination of 8 bacteriophage isolates and 9 bacterial isolates. All of the 8 bacteriophages tested were found to form plaques on more than 1 host, and 4 of them formed plaques on both gram-positive and gram-negative bacterial isolates. Three of the 8 bacteriophages failed to form plaques on their original bacterial host. The experimental result indicates that bacteriophages are an active part of the activated sludge microbial ecosystem, having a very close ecological relationship with their host bacteria.     

Integrated Routing Algorithms for Provisioning “Sub-Wavelength” Connections in IP-Over-WDM Networks

This work focuses on developing and implementing comprehensive unified constraint-based routing algorithms within the generalized multi-protocol label switching framework (GMPLS) to provision sub-wavelength circuits (low-rate traffic streams). Constraint-based routing is further augmented in this work by dynamically routing both an active and another alternate link/node-disjoint backup path at the same time in order to provision a given connection request. This new integrated approach combines both IP routing and optical resource allocation to setup end-to-end connections.