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In this paper, we present a unified model for several well‐known checkpoint/restart protocols. The proposed model is generic enough to encompass both extremes of the checkpoint/restart space, from coordinated approaches to a variety of uncoordinated checkpoint strategies (with message logging). We identify a set of crucial parameters, instantiate them, and compare the expected efficiency of the fault tolerant protocols, for a given application/platform pair. We then propose a detailed analysis of several scenarios, including some of the most powerful currently available high performance computing platforms, as well as anticipated Exascale designs. The results of this analytical comparison are corroborated by a comprehensive set of simulations. Altogether, they outline comparative behaviors of checkpoint strategies at very large scale, thereby providing insight that is hardly accessible to direct experimentation. Copyright © 2013 John Wiley & Sons, Ltd.  相似文献   
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Conductance measurements are reported for s-alkylisothiouronium bromide, iodide and picrate salts in the dipolar aprotic solvent DMSO at 25°C. The data were analysed by Fuoss's equation (1975–1980) for 1:1 electrolytes, from which the values of Λ0, the Gurney's cosphere diameter R and KA are obtained. The results are discussed in the light of the recorded values of the constants KR and KS and the free energy term Gs.  相似文献   
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International Journal of Control, Automation and Systems - In this research, an Optimized Fuzzy-Padé Controller (OFPC) for attitude stabilization of a quadrotor is proposed by using Padé...  相似文献   
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A novel heteropolysaccharide, named cress water soluble polysaccharide (CWSP), was purified from Lepidium sativum seeds. Antioxidant activities and functional properties were characterized thermally using thermal gravimetric analysis (TGA), and the differential scanning calorimeter (DSC) results of CWSP were evaluated. The total antioxidant capacity and the metal chelating activities of CWSP at 3 mg/ml were equivalent to 116.34 µg ascorbic acid and 62.57%, respectively. As for the CWSP that was used for the production of cakes, it was thermally stable, and it presented high water (WHC) and oil holding (OHC) capacities and good emulsion properties. The samples were prepared with different levels of CWSP (0.1. 0.3, and 0.5%) and analyzed during 15 days of storage at room temperature. The obtained results indicated that the addition of CWSP had a significant effect on the texture profile, leading to the increase in all parameters in terms of hardness, springiness, cohesiveness, adhesiveness, and chewiness. Moreover, the reformulation samples presented higher a* and lower L* and b* than the control sample. The sensory evaluation showed that the formulation of cake with 0.3% of CWSP was the most acceptable. Therefore, CWSP was shown to be a new alternative for improving the quality attributes, indicating potent antioxidant activities on the shelf life during the storage of bakery foods.  相似文献   
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Cardiovascular disease (CVD) is one of the major causes of mortality worldwide. Inflammation is the underlying common mechanism involved in CVD. It has been recently related to amino acid metabolism, which acts as a critical regulator of innate and adaptive immune responses. Among different metabolites that have emerged as important regulators of immune and inflammatory responses, tryptophan (Trp) metabolites have been shown to play a pivotal role in CVD. Here, we provide an overview of the fundamental aspects of Trp metabolism and the interplay between the dysregulation of the main actors involved in Trp metabolism such as indoleamine 2, 3-dioxygenase 1 (IDO) and CVD, including atherosclerosis and myocardial infarction. IDO has a prominent and complex role. Its activity, impacting on several biological pathways, complicates our understanding of its function, particularly in CVD, where it is still under debate. The discrepancy of the observed IDO effects could be potentially explained by its specific cell and tissue contribution, encouraging further investigations regarding the role of this enzyme. Thus, improving our understanding of the function of Trp as well as its derived metabolites will help to move one step closer towards tailored therapies aiming to treat CVD.  相似文献   
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