Regional Climate Simulations on EU-INDIA Grid Infrastructures: Methodologies and Performance

In this paper, we present a possible approach to use different Grid infrastructures across Europe and India for regional climate simulations and discuss in details the advantages and limitations in using them. The application taken into consideration is the Regional Climate Model RegCM4, which has been recently re-written for making it more efficient and easier to be fully exploited on any kind of computational infrastructure. We describe here the methods applied to port this package on the Grid infrastructures made available by the EU-IndiaGrid project. We also discuss different approaches, the way to run the model on both European and Indian infrastructures and our promising approach to deal with data management issues. Use of RegCM on Grid infrastructure has further been compared with that on HPC resources. The domain worked upon for these tests is the South-Asia CORDEX domain, which is of great importance for the Indian Summer Monsoon. Our final conclusion is that, for certain class of experiments, RegCM4 model can be efficiently and easily integrated on Grid infrastructures, by means of the procedures described in this paper.     

Ozonation of Selected Molecules Constituting Cellular Matter

Ozonation of purine and pyrimidine bases and of carbohydrates was studies in laboratory experiments. The results showed that nucleobases are much more reactive with molecular ozone in aqueous solution than carbohydrates. Second order rate constants for direct reaction of ozone on purines (adenine and guanine) and on pyrimidines (cytosine, thymine and uracil) ranged from 0.76 × 10³ to 6.8 × 10³ M^-1s^-1at 2°C. The difference of reactivity between these solutes may be attributed to their substituents. As far as carbohydrates are concerned, direct reactions of ozone are very slow k₀₃ ? 0.1 – 0.3 M_-1s_-1 at 20°C, and the results indicated that free radical reactions are predominant in the degradation pathway of carbohydrates by ozone. Some ozonation by-products of monosaccharides (glucose, xylose) and disaccharides (cellobiose) also were identified in this study by means of GC/MS analyses.     

An empirical investigation of Technology Readiness among medical staff based in Greek hospitals

Technology readiness (TR) represents an individual’s mental readiness to accept new technologies. Although the TR scale has been used in many studies, its application in the healthcare context is limited. This paper focuses on identifying the TR profiles of medical staff and to model preference TR variations with respect to computer use, computer knowledge and computer feature demands. The study reports results from a nationwide study conducted in Greece, during a three-year period, which sampled responses from 604 physicians and nurses working in 14 Greek hospitals. Exploratory Structural Equation Modelling analysis is used in order to confirm the structure of the Technology Readiness Index. The results confirm the five groups of the TR taxonomy. Statistical differences were found between classes in information and communication technology (ICT) knowledge, ICT feature demands, hours of use per week as well as ICT use performance, but not in the general use of ICT. The results facilitate comprehension of the factors, which influence the use of ICT by medical staff and, in addition, they convey important policy and managerial implications. In conclusion, medical staff should be treated according to its TR taxonomy classes in order to expedite the acceptance and use of an ICT system.     

The longitudinal impact of enterprise system users’ pre-adoption expectations and organizational support on post-adoption proficient usage

Although enterprise systems (ES) are ubiquitous, many firms report less than stellar payoffs from these costly investments, with underutilization often attributed to failures in the implementation process. Unfortunately, research has not provided sufficient insights into these failures, in part because it has focused on actual usage, as opposed to proficient usage, as the benchmark for successful implementation. Moreover, research has not generally examined how the adoption process unfolds over time, thus overlooking potential underlying mechanisms that may help explain how adopters achieve proficiency. To begin addressing these shortcomings, we study how adopters’ pre-adoption expectations, enacted over time, can influence their post-adoption proficiency, by shaping how and why they spend time using the system during the adoption period. We analyzed time-lagged survey data from 153 financial analysts, required to adopt new ES-based software, at a multinational bank. We found that adopters who hold pre-adoption expectations reflecting greater internal and external motives to adopt the system as well as systematically integrate it into their work routines are more apt to use the system in ways that enhance their cumulative knowledge of it, and subsequently develop higher levels of proficiency post-adoption. Moreover, greater organizational support enhanced the impact of adopters’ expectations on proficiency, except when their actual use is low in which case organizational support had an adverse effect.     

On the Relation of Job Insecurity,Job Autonomy,Innovative Work Behaviour and the Mediating Effect of Work Engagement

European policy is focusing on innovation as a way out of the economic crisis. At the same time, job insecurity is rising as Europe is still in crisis. In this paper, we examine whether job insecurity affects the innovative work behaviour of employees by focusing on the relation between job insecurity, job autonomy, work engagement and innovative work behaviour (IWB). Using employee level survey data, we use structural equation modelling to disentangle the relations between these variables. The partially mediated model shows the best fit with the data. This model shows that job insecurity and autonomy are both directly and indirectly, through work engagement, related with IWB. For autonomy these relations are positive, while they are negative (and smaller) for job insecurity. Moreover, a negative covariance is observed between job insecurity and autonomy.     

IT capability and organizational performance: the roles of business process agility and environmental factors

The business value of information technology (IT) has been one of the top concerns of both practitioners and scholars for decades. Numerous studies have documented the positive effects of IT capability on organizational performance but our knowledge of the processes through which such gains are achieved remains limited due to a lack of focus on the business environment. Such a linkage therefore remains the subject of debate in the information systems literature. In this study, we fill this gap by investigating the mediating role of business process agility and the moderating roles of environmental factors. On the basis of matched survey data obtained from 214 IT and business executives from manufacturing firms in China, our analyses show that even though firm-wide IT capability presents the characteristics of rarity, appropriability, non-reproducibility, and non-substitutability, its impact on organizational performance is fully mediated by business process agility. Our results also show that the impact of the environment is multifaceted and nuanced. In particular, environmental hostility weakens the effect of IT capability on business process agility, while environmental complexity strengthens it. The theoretical and practical implications of this study, and its limitations, are also discussed.     

Integrated clinical pathway management for medical quality improvement – based on a semiotically inspired systems architecture

Clinical pathway is an approach to standardise care processes to support the implementations of clinical guidelines and protocols. It is designed to support the management of treatment processes including clinical and non-clinical activities, resources and also financial aspects. It provides detailed guidance for each stage in the management of a patient with the aim of improving the continuity and coordination of care across different disciplines and sectors. However, in the practical treatment process, the lack of knowledge sharing and information accuracy of paper-based clinical pathways burden health-care staff with a large amount of paper work. This will often result in medical errors, inefficient treatment process and thus poor quality medical services. This paper first presents a theoretical underpinning and a co-design research methodology for integrated pathway management by drawing input from organisational semiotics. An approach to integrated clinical pathway management is then proposed, which aims to embed pathway knowledge into treatment processes and existing hospital information systems. The capability of this approach has been demonstrated through the case study in one of the largest hospitals in China. The outcome reveals that medical quality can be improved significantly by the classified clinical pathway knowledge and seamless integration with hospital information systems.     

Tribological behavior of pure and graphite‐filled polyimides under atmospheric conditions

As the use of common engineering plastics in tribological systems is limited to low sliding velocities and low loads because of creep and insufficient temperature resistance, there is increasing interest in application of high‐performance polymers such as polyimides, characterized by their ability to maintain favorable mechanical properties up to their melting point. However, for practical design, tribotesting remains necessary for determination of the material's performance under a given contact situation. In this article, two commercially available polyimides are tested at relatively high sliding velocities and contact pressures under atmospheric conditions of temperature and humidity. A consistent overview of tendencies in friction and wear for pure polyimides as a function of applied normal loads and sliding velocities is given. Addition of 15% by weight graphite powder as internal solid lubricant strongly influences friction and wear. Its behavior is compared with pure polyimide grades and differences are discussed in relation with experimental measured bulk‐temperatures. A linear temperature law is derived as a function of pv‐levels and a steady‐state condition is found at different temperature levels, in accordance with thermal conductivity of the polymer bulks. In case of graphite additives, a steady state in temperature coincides with the regime condition of wear rate.     

The removal of hydrogen sulfide with manganic sorbent in a high-temperature fluidized-bed reactor

The removal of hydrogen sulfide (H₂S) from simulated gas was carried out in a batch type fluidized-bed reactor using natural manganese ore (NMO), which consists of several metal oxides (MnO_x: 51.85%, FeO_y: 3.86%, CaO: 0.11%). The H₂S breakthrough curves were obtained by changing temperature, gas velocity, initial H₂S concentration, and aspect ratio. Moreover, the effects of the particle size and the particle-mixing fraction on H₂S removal were investigated in a binary system of different particle size. From this study, H₂S removal efficiency increased with increasing temperature but decreased with increasing excess gas velocity. The breakthrough time for H₂S decreased as the gas velocity increased, which leads to reducing gas-solid contacting due to gas bypassing in a fluidized bed reactor. Improvement of H₂S removal efficiency in continuous process can be expected from the results of the binary particle system with different size in a batch experiment. The NMO could be considered as a potential sorbent in H₂S removal.     

Inhibition of oxygen evolution by zaluzanin C

The inhibition of ATP synthesis, proton uptake, and electron transport (basal, phosphorylating, and uncoupled) from water to methylviologen by zaluzanin C indicates that it acts as an electron transport inhibitor. Uncoupled photosystem I electron transport rate was not affected by zaluzanin C; however, uncoupled photosystem II electron flow from water to 2,3,5,6-tetramethyl phenylenediamine and from water to silicomolybdate was inhibited, but electron transport from diphenylcarbazide to silicomolybdate was not affected. We conclude that the site of inhibition by zaluzanin C is located at the oxygen evolution level.