Development of a pressure control system for brace treatment of scoliosis

Bracing is a common nonsurgical treatment for scoliosis, but its effectiveness has been debated. Some clinical studies have shown efficacy of brace treatment is correlated to how the brace has been worn. The more often the patients wear their braces to the prescribed tightness as well as the prescribed length of wear each day, the better the treatment outcome. A system of four wireless pressure control devices was developed to understand brace wear-time and regulate a target pressure range at the brace-body interface. Each pressure control device could function independently and be embedded in the brace at key pressure areas. Such a system could improve the quality of brace wear-making the treatment more effective and refining our understanding of the three-pressure-point brace treatment concept during daily activities. This paper reports the system development and validation. The system was tested on four healthy subjects for 2 h without pressure regulation and 2 h with regulation. The results show that the pressure regulation doubled the time spent in a desired pressure range on average (from 31% to 62%). Brace-wear time was logged correctly. The system was also validated through a seven-day continuous test, and a fully charged battery could run for 30 days without requiring recharge.     

高级电视中的灵巧集成技术

接要:介绍了典型的LCDTV为系统集成提供的模拟接口、数字接口,减少了内部连线,分析了“灵巧集成”的复杂度问题。采用在单芯片上集成多种接口和控制器功能的大规模集成电路可减少元器件的数量并且提高生产能力,但是有一定的风险。     

设计直接转换I／Q解调器接收器时对IP2和IP3的考虑

与传统超外差式接收器架构相比,直接转换接收器架构有许多优点.因为直接转换接收器不容易受镜频信号干扰,所以它降低了对RF前端带通滤波的要求.RF带通滤波器仅需要衰减较强的带外信号,以防止它们使前端过载.另外,直接转换接收器无须IF放大器和带通滤波器.RF输入信号直接转换成基带信号,在这种情况下,放大和滤波都容易了许多.这种接收器的总体复杂性降低了,器件数目也减少了.     

A quantitative comparison of synaptic density following perfusion versus immersion fixation in the rat cerebral cortex

The main objective of the present study was to perform an unbiased comparison of immersion vs. perfusion techniques to assess whether we could use the former to quantify synapses through electron microscopy (EM). Using the immersion technique is ideally suited for instances in which the specimen under study could not be perfused under the standard EM protocol. Our results suggest that, despite suboptimal qualitative results, fixation by immersion allows for adequate quantification of synapses.     

Extraction/conversion of geometric dimensions and tolerances for machining features

It is important for a feature-based system to preserve feature integrity during feature operation, especially when feature interaction occurs. The paper presents a feature conversion approach to convert design features used in a design model into machining features for the downstream applications. This process includes both form features (geometric information) and non-geometric features conversion. Most researchers have concentrated on geometric information extraction and conversion without tackling the important problem of non-geometric feature information. This paper focuses on the extraction and conversion of feature geometric dimensions and tolerances (GD&T) for downstream machining application.The main barrier to the integration of a feature-based CAD/CAPP/CAM system – feature interaction – is discussed in this paper, which alters design features in their geometries and non-geometric information. How to identify and validate these feature dimensions and tolerances is one of the key issues in feature interaction conversion. The development of robust methodologies for preserving feature integrity for use in process planning application is the main thrust of the work reported in this paper.     

Understanding affective commitment in social virtual worlds: The role of cultural tightness

Understanding how cultural differences affect the formation of users’ affective commitment (ACO) to social virtual world (SVW) services is a critical but understudied issue. Using a novel, norm-based cultural approach, we introduce cultural tightness (CT) to capture cultural differences in users’ collective environment and postulate a model that investigates the contingent effects of CT on the relationships between ACO and its drivers. A two-level analysis of survey data gathered from 400 field users of an influential SVW service and secondary data of CT reveals that the effects of satisfaction, calculative commitment, and subjective norm on ACO are contingent on CT.     

Microbial community structure in activated sludge floc analysed by fluorescence in situ hybridization and its relation to floc stability

The efficiency of activated sludge treatment plants is dependent on the solid-liquid separation properties of the activated sludge. A critical parameter is the stability of the microbial flocs. Weak flocs deflocculate easily leaving increased concentrations of suspended solids in the effluent. The knowledge about how different bacteria are attached to the flocs and their influence on the bioflocculation is limited. In this study, the deflocculation of different phylogenetic groups of bacteria in activated sludge from a full scale plant was investigated. The experiments were carried out by using a shear method where the sludge flocs are deflocculated under controlled shear conditions. The degree of deflocculation was measured as increase in turbidity of the supernatant. Identification and quantification of the microbial community structure of both total activated sludge and deflocculated bacteria were conducted with group-specific gene probes for broad groups of bacteria (Alphaproteobacteria, Betaproteobacteria, Gammaproteobacteria and Actinobacteria) and fluorescence in situ hybridization (FISH). The microbial community structure of the deflocculated bacteria was different compared to the total activated sludge with a higher abundance of Gammaproteobacteria in the supernatant indicating that different groups of bacteria are bound with different strength to the floc surface. The results show that the bacteria in the outer parts of the flocs are relatively loosely bound to the floc matrix and can be easily eroded from the surface when exposed to shear.     

Monitoring diet effects via biofluids and their implications for metabolomics studies

The effect of diet on metabolites found in rat urine samples has been investigated using nuclear magnetic resonance (NMR) and a new ambient ionization mass spectrometry experiment, extractive electrospray ionization mass spectrometry (EESI-MS). Urine samples from rats with three different dietary regimens were readily distinguished using multivariate statistical analysis on metabolites detected by NMR and MS. To observe the effect of diet on metabolic pathways, metabolites related to specific pathways were also investigated using multivariate statistical analysis. Discrimination is increased by making observations on restricted compound sets. Changes in diet at 24-h intervals led to predictable changes in the spectral data. Principal component analysis was used to separate the rats into groups according to their different dietary regimens using the full NMR, EESI-MS data or restricted sets of peaks in the mass spectra corresponding only to metabolites found in the urea cycle and metabolism of amino groups pathway. By contrast, multivariate analysis of variance from the score plots showed that metabolites of purine metabolism obscure the classification relative to the full metabolite set. These results suggest that it may be possible to reduce the number of statistical variables used by monitoring the biochemical variability of particular pathways. It should also be possible by this procedure to reduce the effect of diet in the biofluid samples for such purposes as disease detection.     

Diode-pumped Nd:YAG laser with 38 W average power and user-selectable, flat-in-time subnanosecond pulses

A diode-pumped injection-seeded Nd:YAG laser system with an average output power of 38 W is described. The laser operates at 300 Hz with pulse energies up to 130 mJ. The temporal pulse shape is nominally flat in time and the pulse width is user selectable from 350 to 600 ps. In addition, the spatial profile of the beam is near top hat with contrast <10%.     

Student-based Assessment in a Multi-disciplinary Problem-based Learning Environment

Engineering education in Australia must respond to a changing environment so that the nation continues to produce engineering graduates able to contribute towards the development of society in the face of local, national and international pressures. To address these changes, engineering schools are introducing teaching initiatives aimed at developing a range of skills including people, problem-solving and self-directed learning skills. Many of these programs encourage student learning through active participation with the subject matter; however, they also place a considerable burden upon staff because of the assessment load required to ensure that students attain the required competencies. Student-based assessment strategies are often proposed as techniques for enhancing student learning by transferring the ownership and some of the responsibility for the assessment process to the student body. This paper examines the literature relating to student-based assessment and presents some assessment strategies suitable for a problem-based learning course in embedded systems design.