Weight function for an external circumferential semielliptical crack in a cylinder

In this paper, the weight function was extracted at the deepest point of a semielliptical circumferential crack. The crack is assumed to exist on the outer surface of the cylinder. For this purpose, the three‐dimensional finite element method was accomplished to specify two reference loads, which are indispensable for determining the weight function. The verification study confirms the accuracy of the derived weight function under prescribed mechanical loading on the crack surfaces. There is consistency among the solution results compared with those in the literature. The second part describes the application of the weight function for the thermal boundary conditions. Steady‐state thermal stress intensity factors are demonstrated using the weight function and presented as a closed‐form solution. The results were compared with the finite element data on the special case of thermal loading, and good agreement is obtained.     

Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome

Background: Obesity coexists with variable features of metabolic syndrome, which is associated with dysregulated metabolic pathways. We assessed potential associations between serum metabolites and features of metabolic syndrome in Arabic subjects with obesity. Methods: We analyzed a dataset of 39 subjects with obesity only (OBO, n = 18) age-matched to subjects with obesity and metabolic syndrome (OBM, n = 21). We measured 1069 serum metabolites and correlated them to clinical features. Results: A total of 83 metabolites, mostly lipids, were significantly different (p < 0.05) between the two groups. Among lipids, 22 sphingomyelins were decreased in OBM compared to OBO. Among non-lipids, quinolinate, kynurenine, and tryptophan were also decreased in OBM compared to OBO. Sphingomyelin is negatively correlated with glucose, HbA1C, insulin, and triglycerides but positively correlated with HDL, LDL, and cholesterol. Differentially enriched pathways include lysine degradation, amino sugar and nucleotide sugar metabolism, arginine and proline metabolism, fructose and mannose metabolism, and galactose metabolism. Conclusions: Metabolites and pathways associated with chronic inflammation are differentially expressed in subjects with obesity and metabolic syndrome compared to subjects with obesity but without the clinical features of metabolic syndrome.     

Three-Point Bending Behavior of Foam-Filled Conventional and Auxetic 3D-Printed Honeycombs

Cellular hexagonal (conventional) and re-entrant (auxetic) honeycombs are applicable in automotive, construction, and protective engineering. Auxetic structures own excellent energy absorption and flexural behavior due to their special deformation under loading. This work explores the performance of additively manufactured polylactic acid (PLA)- and thermoplastic polyurethane (TPU)-based hexagonal and re-entrant honeycombs under flexural loading via experimental three-point bending (TPB) tests and finite-element analysis (FEA). 3D-printed conventional and auxetic cellular structures are filled with polyurethane (PU) foam and their energy absorption capacity and flexural modulus are compared with hollow structures. The results reveal that TPU-based structures’ energy absorption capacity and flexural modulus improve significantly, whereas the PLA-based structures’ performance deteriorates when filled with PU foam. Moreover, re-entrant honeycombs are better reinforced with foam in comparison to the hexagonal honeycombs, as the re-entrant's unit cell is more spacious than the hexagonal unit cell. Finally, parametric studies are performed via FEA to investigate the influence of geometric parameters of structures and flexural loading setup on the performance of the honeycombs, showing that structures with thicker struts and higher cell angle can act stiffer under TPB. The outcomes of this research indicate the promising performance of foam-filled TPU-based auxetic structures.     

A stabilized foam formulation using FTP-SDS surfactants for wettability alteration and flow diversion in carbonate fractured oil reservoirs

Foam injection contributes to improved oil recovery through flow diversion, reduction of interfacial tension (IFT), and wettability alteration of the rock while its stability is an issue. In this article, nitrogen-foam was optimally formulated using fluorocarbon tubiguard protect (FTP) surfactant stabilized with sodium dodecyl sulfate (SDS) co-surfactant that was later experimentally considered for oil recovery in a fractured carbonate rock taken from an oil field in the Middle East. The results showed that the 5:1 volume ratio of fluorocarbon surfactant and SDS (FS51) generates a stable foaming agent with ability of changing the wettability of the carbonate rock surfaces to an intermediate gas-wet state. A series of core-flood experiments at HPHT conditions were also carried out and designed to properly represent matrix-fracture media using both a horizontally and vertically oriented setup. The oil saturated cores were flooded with nitrogen gas first followed by foam injection. It was concluded that foam can divert the gas to flow from fractures to the matrix blocks and result in a significant oil recovery. The contact angle tests that performed after core-flood experiments revealed the wettability changes of fracture surfaces from an oil-wet to a gas-wet state. This allows gas to be imbibed into the matrix blocks by capillary force and results in enhancement of ultimate oil recovery. This study revealed that trapped oil in matrixes blocks that had not been drained during the gas injection process could be produced by designing a stable foam that sustainably diverts injected fluid from fractures to matrix zone.     

Green Synthesis of Chitosan-Coated Silver Nanoparticle,Characterization, Antimicrobial Activities,and Cytotoxicity Analysis in Cancerous and Normal Cell Lines

Journal of Inorganic and Organometallic Polymers and Materials - The production of silver nanoparticles (AgNPs) using chemical synthesis routes require hazardous and toxic solvents. Nowadays, there...     

CO2 utilization for methanol production; Optimal pathways with minimum GHG reduction cost

Mitigating CO₂ emissions from industries and other sectors of our economy is a critical component of building a sustainable economy. This paper investigates two different methanol synthesis routes based on CO₂ utilization (CO₂ capture and utilization [CCU], and tri-reforming of methane [TRM]), and compares the results with the conventional methanol production using natural gas as the feedstock (NG-MeOH). A comprehensive techno-economic analysis (TEA) model that includes the findings of the life cycle assessment (LCA) models of methanol production using various CO₂ utilization pathways is conducted. Economic analysis is conducted by developing a cost model that is connected to the simulation models for each production route. Compared to the conventional process (with a GHG emission of 0.6 kg CO₂/kg MeOH), the lifecycle GHG reduction of 1.75 and 0.41 kg CO₂/kg MeOH are achievable in the CCU and TRM pathways, respectively. Furthermore, the results indicate that, under current market conditions and hydrogen production costs, methanol production via CO₂ hydrogenation will result in a cost approximately three times higher than that of the conventional process. The integrated TEA–LCA model shows that this increased cost of production equates to a required life cycle GHG reduction credit of $279 to $422 per tonne of CO₂ utilized, depending on construction material and selected pathway. Additionally, when compared to the CO₂ hydrogenation route, the tri-reforming process (TRM-MeOH) can result in a 42% cost savings. Furthermore, a minimum financial support of $56 per tonne utilized CO₂ will be required to make the TRM-MeOH process economically viable.     

Fixed-time fault-tolerant control of uncertain MIMO switched interconnected systems subject to state delay,unknown control directions,and quantized nonlinear inputs

This paper investigates design of an adaptive fixed-time fault-tolerant decentralized controller for a class of uncertain multi-input multi-output (MIMO) switched large-scale non-strict interconnected systems under arbitrary switching subject to unknown control directions, quantized nonlinear inputs, actuator failures unknown external disturbances, and unmodeled dynamics. In addition to interconnected terms, time-varying delayed interconnected terms have been considered in the system model which makes it more general than previous works in the literature. The proposed controller can handle switched systems with unknown switching signal and different types of input nonlinearities including, saturation, backlash, and dead-zone. The singularity problem in designing the fixed time controller has been solved. The quantizer and actuators fault parameters are assumed to be unknown. The Razumikhin lemma has been used to deal with the delayed interconnected terms. To cope with the system unknown dynamics, neural networks (NNs) have been applied and by updating the maximum norms of the networks weight vectors the computational load has been reduced. The explosion of complexity occurring in the traditional back-stepping technique has been avoided by applying dynamic surface control (DSC). Finally, by defining an appropriate common Lyapunov function (CLF), fixed-time convergence of system outputs and the closed-loop system stability have been established. The effectiveness of the proposed controller has been shown via simulation study.     

Recapitulating Antioxidant and Antibacterial Compounds into a Package for Tissue Regeneration: Dual Function Materials with Synergistic Effect

Oxidative damage and infection can prevent or delay tissue repair. Moreover, infection reinforces reactive oxygen species (ROS) formation, which makes the wound's condition even worse. Therefore, the need for antioxidant and antibacterial agents is felt for tissue regeneration. There are emerging up-and-coming biomaterials that recapitulate both properties into a package, offering an effective solution to turn the wound back into a healing state. In this article, the principles of antioxidant and antibacterial activity are summarized. The review starts with biological aspects, getting the readers to familiarize themselves with tissue barriers against infection. This is followed by the chemistry and mechanism of action of antioxidant and antibacterial materials (dual function). Eventually, the outlook and challenges are underlined to provide where the dual-function biomaterials are and where they are going in the future. It is expected that the present article inspires the designing of dual-function biomaterials to more advanced levels by providing the fundamentals and comparative points of view and paving the clinical way for these materials.