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151.
152.
O van der Heijden HC Chiu TC Park H Takahashi VA LiVolsi JI Risinger JC Barrett A Berchuck AC Evans K Behbakht AW Menzin PC Liu I Benjamin MA Morgan SA King SC Rubin J Boyd 《Canadian Metallurgical Quarterly》1998,23(4):243-247
The degree and nature of patient involvement in consultations with health professionals influences problem and needs recognition and management, and public accountability. This paper suggests a framework for understanding the scope for patient involvement in such consultations. Patients are defined as co-producers of formal health services, whose potential for involvement in consultations depends on their personal rights, responsibilities and preferences. Patients' rights in consultations are poorly defined and, in the National Health Service (NHS), not legally enforceable. The responsibilities of patients are also undefined. I suggest that these are not to deny, of their own volition, the rights of others, which in consultations necessitate mutuality of involvement through information-exchange and shared decision-making. Preferences should be met insofar as they do not militate against responsibilities and rights. 相似文献
153.
P Barrett G Davidson DG Hazlerigg MA Morris AW Ross PJ Morgan 《Canadian Metallurgical Quarterly》1998,139(1):163-171
154.
155.
DK Robbins MA Castles DJ Pack VO Bhargava SJ Weir 《Canadian Metallurgical Quarterly》1998,19(7):455-463
The pharmacokinetics and dose proportionality of fexofenadine, a new non-sedating antihistamine, and its enantiomers were characterized after single and multiple-dose administration of its hydrochloride salt. A total of 24 healthy male volunteers (31 +/- 8 years) received oral doses of 20, 60, 120 and 240 mg fexofenadine HCl in a randomized, complete four-period cross-over design. Subjects received a single oral dose on day 1, and multiple oral doses every 12 h on day 3 through the morning on day 7. Treatments were separated by a 14-day washout period. Serial blood and urine samples were collected for up to 48 h following the first and last doses of fexofenadine HCl. Fexofenadine and its R(+) and S(-) enantiomers were analysed in plasma and urine by validated HPLC methods. Fexofenadine pharmacokinetics were linear across the 20-120 mg dose range, but a small disproportionate increase in area under the plasma concentration-time curve (AUC) (< 25%) was observed following the 240 mg dose. Single-dose pharmacokinetics of fexofenadine were predictive of steady-state pharmacokinetics. Urinary elimination of fexofenadine played a minor role (10%) in the disposition of this drug. A 63:37 steady-state ratio of R(+) and S(-) fexofenadine was observed in plasma. This ratio was essentially constant across time and dose. R(+) and S(-) fexofenadine were eliminated into urine in equal rates and quantities. All doses of fexofenadine HCl were well tolerated after single and multiple-dose administration. 相似文献
156.
在10 ̄(-5)_eV-20MeV中子能量范围内对天然汞的中子核数据进行评价。评价内容包括总的、弹性、去弹、总非弹、30条分立能级、连续非弹、(n,2n)、(n,3n,)、(n,n'P)、(n,n'α)、(n,P)、(n,α)、(n,d)、(n,t)和(n,γ)截面;次级中子角分布;双微分截面(DDCS);γ射线产生数据等。评价根据有效实验数据(至1993年)和UNF-92 ̄[1]理论计算。评价数据以ENDF/B6格式录入中国评价核数据库CENDL-2.1版(MAT=1800),并提供核工程有关部门使用。 相似文献
157.
AE Calogero F Nicoletti MA Palumbo N Burrello M Di Mauro M Lunetta K Bendtzen A Cianci 《Canadian Metallurgical Quarterly》1998,10(10):814-818
Myoclonus of the middle ear is a rare condition characterized by abnormal repetitive muscle contractions of the tympanic cavity. In this paper we describe what we believe is the first reported case of continuous high-frequency objective tinnitus caused by middle ear myoclonus. During exploratory tympanomastoidectomy it was hypothesized that a small dural arteriovenous malformation not identified on previous tests was the cause of the tinnitus. However, complete disappearance of the tinnitus during administration of curare for anesthesia led us to believe that the tinnitus might have been caused by myoclonus of the middle ear. Sectioning of the stapedius and tensor tympani tendons rendered the patient asymptomatic and confirmed the diagnosis of middle ear myoclonus. At follow-up of one year, the patient's quality of life had improved substantially; the tinnitus did not recur and she no longer had vertigo. 相似文献
158.
159.
Urinary tract abnormalities are fairly common in the perinatal period. Ultrasonography is an effective diagnostic tool for identifying fetal urinary tract anomalies and can be helpful in establishing prognosis and guiding treatment decisions. The sonographer is encouraged to characterize and localize the fetal urinary tract abnormality when identified. In doing so, the correct diagnosis can be selected from the differential possibilities, providing vital clinical information needed to develop a care plan for both the pregnant woman and her fetus. 相似文献
160.
MJ Kallio L Salmenper? MA Siimes J Perheentupa H Gylling TA Miettinen 《Canadian Metallurgical Quarterly》1998,43(3):381-385
Fatty acid uptake is partly controlled by the FATP gene family, of which at least five members are known in mice. Using the mmFATP1 cDNA as hybridization probe, a 1.6 kb partial cDNA clone was isolated from a human heart cDNA library. With 5' and 3' RACE procedures, the complete cDNA was isolated. Sequence comparisons with its mouse homologues identified this clone as hsFATP4. 相似文献