非均匀介质透射波Goos-Hnchen位移的研究

基于不变嵌入理论,推导出电磁波入射到非均匀介质平板,反射系数和透射系数的耦合波方程;利用稳态相位方法,分析了透射波Goos-Hnchen(GH)位移的性质。通过数值计算,研究了入射角和介质厚度对透射率及GH位移的影响。结果显示,介质厚度一定时,透射率在特定角度具有极大值,对应的透射波发生负的GH位移,并且位移绝对值最大;入射角不变时,透射率和GH位移随厚度呈周期性变化,厚度增加,透射率呈下降趋势,但GH位移呈增大趋势。GH位移受入射角和介质厚度的影响很大,因此,可以通过调节厚度和入射角,获得合适的透射率和GH位移。     

利用故障录波数据对负荷模型进行校核的探讨

介绍了故障录波装置的特点,结合内蒙古自治区负荷特点,探讨了利用故障录波数据对负荷模型进行校核的方法。利用萨拉齐处故障录波数据进行负荷模型校验,结果表明,仿真得到的功率曲线与故障录波数据得到的功率曲线吻合得很好,说明所建立的负荷模型是合理的。     

Comprehensive Analysis of hsa-miR-654-5p’s Tumor-Suppressing Functions

The pivotal roles of miRNAs in carcinogenesis, metastasis, and prognosis have been demonstrated recently in various cancers. This study intended to investigate the specific roles of hsa-miR-654-5p in lung cancer, which is, in general, rarely discussed. A series of closed-loop bioinformatic functional analyses were integrated with in vitro experimental validation to explore the overall biological functions and pan-cancer regulation pattern of miR-654-5p. We found that miR-654-5p abundance was significantly elevated in LUAD tissues and correlated with patients’ survival. A total of 275 potential targets of miR-654-5p were then identified and the miR-654-5p-RNF8 regulation axis was validated in vitro as a proof of concept. Furthermore, we revealed the tumor-suppressing roles of miR-654-5p and demonstrated that miR-654-5p inhibited the lung cancer cell epithelial-mesenchymal transition (EMT) process, cell proliferation, and migration using target-based, abundance-based, and ssGSEA-based bioinformatic methods and in vitro validation. Following the construction of a protein–protein interaction network, 11 highly interconnected hub genes were identified and a five-genes risk scoring model was developed to assess their potential prognostic ability. Our study does not only provide a basic miRNA-mRNA-phenotypes reference map for understanding the function of miR-654-5p in different cancers but also reveals the tumor-suppressing roles and prognostic values of miR-654-5p.     

A vacuum ultraviolet laser with a submicrometer spot for spatially resolved photoemission spectroscopy

Vacuum ultraviolet(VUV)lasers have demonstrated great potential as the light source for various spectroscopies,which,if they can be focused into a small beam spot,will not only allow investigation of mesoscopic materials and structures but also find application in the manufacture of nano-objects with excellent precision.In this work,we report the construction of a 177 nm VUV laser that can achieve a record-small(〜0.76 μm)focal spot at a long focal length(~45 mm)by using a flat lens without spherical aberration.The size of the beam spot of this VUV laser was tested using a metal grating and exfoliated graphene flakes,and we demonstrated its application in a fluorescence spectroscopy study on pure and Tm3+-doped NaYF4 microcrystals,revealing a new emission band that cannot be observed in the traditional up-conversion process.In addition,this laser system would be an ideal light source for spatially and angleresolved photoemission spectroscopy.     

极大节旋藻(Arthrospira maxima)生物钟基因kaiC的克隆及分析

以kaiC基因簇部分已知序列为引物设计位点,采用PCR反应池法从节旋藻基因组fosmid文库中筛选到kaiC基因克隆,通过步移测序获得了kaiC基因全长序列。kaiC基因编码区长1554bo,基因GC碱基含量平均为41．76％,密码子第三位明显偏向于U。在基因上游385bp范围内发现一个可能的启动子序列和一些基因调控元件。KaiC蛋白分析发现了Walker A、DXXG、不完整的Walker B等重要模体和具有催化作用的功能位点。Southem杂交的结果证明kaiC基因在极大节旋藻中为单拷贝。极大节旋藻kaiC基因的特殊结构特征为研究kai基因簇的进化提供了重要的启示。     

海阔天空的乔迁工程

<正>首钢搬迁调整这一史无前例的国家工程将对北京市产生经济“减重”、社会“增压”、环境“减负”、空间“释放”四大效应。而挪一步海阔天空的首钢依然保持浓厚的首都情结,继续在北京开发建设创意产业园区,着力发展总部经济,将以创新的平台提升北京市产业的能级;以创优的平台增强北京市产业的实力;以创业的平台集合高素质的人才队伍;     

冷轧CVC和DSR板形控制技术之比较

根据多年的生产实践总结、理论分析以及基于有限元方法的数值仿真,从板形控制实绩、操作维护经验、板形调控功效、板形控制能力与特性和板形控制策略与模型等方面,对CVC4技术和DSR技术作出了评价和比较,以便有助于认识和选用此2项板形技术.     

Evaluating interfaces with children

Children are very different from adults—they have developing motor skills, limited reach, short attention spans, limited exposure to traditional user interfaces and social protocols. How do we evaluate user interfaces for children? In this paper, we present four evaluative techniques that we have successfully used with children.     

功能空间的综合设计理念

本方案是以公共建筑为主的大型酒店宾馆设计,所在地位于某市中心繁华地段。方案充分考虑了建筑物所出地段的建筑环境,从城市角度出发,确定建筑物的体量、体型。