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排序方式: 共有1433条查询结果,搜索用时 15 毫秒
61.
Larisa I. Privalova Boris A. Katsnelson Nadezhda V. Loginova Vladimir B. Gurvich Vladimir Y. Shur Yakov B. Beikin Marina P. Sutunkova Ilzira A. Minigalieva Ekaterina V. Shishkina Svetlana V. Pichugova Ludmila G. Tulakina Svetlana V. Beljayeva 《International journal of molecular sciences》2014,15(11):21538-21553
We used stable water suspensions of copper oxide particles with mean diameter 20 nm and of particles containing copper oxide and element copper with mean diameter 340 nm to assess the pulmonary phagocytosis response of rats to a single intratracheal instillation of these suspensions using optical, transmission electron, and semi-contact atomic force microscopy and biochemical indices measured in the bronchoalveolar lavage fluid. Although both nano and submicron ultrafine particles were adversely bioactive, the former were found to be more toxic for lungs as compared with the latter while evoking more pronounced defense recruitment of alveolar macrophages and especially of neutrophil leukocytes and more active phagocytosis. Based on our results and literature data, we consider both copper solubilization and direct contact with cellular organelles (mainly, mitochondria) of persistent particles internalized by phagocytes as probable mechanisms of their cytotoxicity. 相似文献
62.
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64.
Nadezhda S. Tian Tamara K. Meleshko Galina A. Polotskaya Iosif V. Gofman Anna V. Kashina Nina V. Kukarkina Elena N. Vlasova Zoolsho F. Zoolshoev Alexander V. Yakimansky 《Polymer Engineering and Science》2020,60(3):481-490
Composite films based on polyamide (poly(m-phenylene-iso-phthalamide)) (PA) and a brush-like polymer with polyimide (PI) backbone and side poly(methyl methacrylate) chains (PI-PMMA) were prepared by mixing individual solutions of PA and PI-PMMA and subsequent film casting. Macromolecular brushes with the same backbone length and density of side chains but with various lengths of side PMMA chains were synthesized via activator generated by electron transfer atom transfer radical polymerization. Interactions between PA and PI-PMMA, as well as distribution of PI-PMMA filler inside the PA matrix, were studied by viscometry, dynamic light scattering, differential scanning calorimetry, scanning electron microscopy, and IR spectroscopy. The mechanical properties of polymer samples were also investigated. Microphase separation was revealed in PA/PI-PMMA films. The length of side chains influences interactions between PA and PI-PMMA. At the same time, the degree of reduction in the rigidity parameters and in the elasticity parameter depends on the side chain length. Diffusion membranes were prepared on the basis of compositions with the best mechanical properties; these membranes proved to be highly efficient in pervaporation of methanol–hexane mixture. It was established that the fluxes and separation factors of the studied membranes are several times higher as compared to the corresponding characteristics of known commercial membranes. POLYM. ENG. SCI., 60:481–490, 2020. © 2019 Society of Plastics Engineers 相似文献
65.
Nadezhda Todorova Miroslav Rangelov Vanya Bogoeva Vishnya Stoyanova Anna Yordanova Ginka Nikolova Hristo Georgiev Daniela Dimitrova Safa Mohedin Katerina Stoyanova Ivanka Tsacheva 《International journal of molecular sciences》2021,22(15)
We addressed the issue of C1q autoantigenicity by studying the structural features of the autoepitopes recognized by the polyclonal anti-C1q antibodies present in Lupus Nephritis (LN) sera. We used six fractions of anti-C1q as antigens and selected anti-idiotypic scFv antibodies from the phage library “Griffin.1”. The monoclonal scFv A1 was the most potent inhibitor of the recognition of C1q and its fragments ghA, ghB and ghC, comprising the globular domain gC1q, by the lupus autoantibodies. It was sequenced and in silico folded by molecular dynamics into a 3D structure. The generated 3D model of A1 elucidated CDR similarity to the apical region of gC1q, thus mapping indirectly for the first time a globular autoepitope of C1q. The VH CDR2 of A1 mimicked the ghA sequence GSEAD suggested as a cross-epitope between anti-DNA and anti-C1q antibodies. Other potential inhibitors of the recognition of C1q by the LN autoantibodies among the selected recombinant antibodies were the monoclonal scFv F6, F9 and A12. 相似文献
66.
Based on the data on chemical binding of the salts of ten metals from aqueous solutions by polycaproamide fibres, the metal cations were divided into four groups as a function of the concentration of the salt solutions and their chemisorption power. Copper cations are most prone to chemisorption by PCA fibres and their chemisorption index is one order of magnitude higher than the index for cations of the other metals. 相似文献
67.
Felix Rivkin Irina Kuznetsova Nadezhda Ivanova Sergey Suhodolsky 《Soil Mechanics and Foundation Engineering》2002,39(1):42-43
Soil Mechanics and Foundation Engineering - 相似文献
68.
S. V. Bulyarskii O. V. Pyatilova A. V. Tsygantsov A. S. Basaev V. A. Galperin A. A. Pavlov Yu. P. Shaman 《Semiconductors》2010,44(13):1718-1722
A fundamental thermodynamic model of formation of catalyst clusters for growing carbon nanotubes has been developed and model
predictions have been compared with the experimental data. An expression for the size distribution function of clusters, depending
on the conditions of their formation, is obtained. It is shown that surface tension plays an important role in the cluster
formation. The surface tension coefficient for iron clusters at 950°C is determined. 相似文献
69.
Dangsheng Su Nadezhda I. Maksimova Vladimir L. Kuznetsov Robert Schlögl Nicolas Keller 《Carbon》2007,45(11):2145-2151
The catalytic properties of sp3-hybridized ultra-dispersed diamond and sp2-hybridized onion-like carbon in the oxidative dehydrogenation of ethylbenzene to styrene were investigated, highlighting the structure sensitivity of the reaction. The sp3-carbon led initially to C-C cleavage and benzene formation, while a switchover of the main reaction pathway into the styrene formation occurred with time on stream due to the formation of surface sp2 carbon, required for the selective styrene formation. This was confirmed by the behavior and the high stable styrene selectivity shown by onion-like carbons. High temperature oxygen pre-treatment created catalytically active species at the sp2 carbon surface, confirming that a high thermal stability carbon-oxygen complex was the active surface site for forming styrene. 相似文献
70.
O. S. Pavlov N. N. Kulov S. Yu. Pavlov 《Theoretical Foundations of Chemical Engineering》2009,43(6):856-860
A technological design of reactive distillation processes (catalytic distillation) is discussed that applies liquid-flooded
catalytic zones with a cocurrent-cross flow of the liquid, into each of which only a portion of the vapor stream is passed
from the zone located below. This allows the cross section of the catalytic zones to be multiply reduced and the local excessive
heating in them to be completely eliminated. 相似文献