Experiments on in-vessel melt coolability in the EC-FOREVER Program

This paper reports the results from the experiments conducted on the coolability of corium melt during a severe accident scenario when the bottom head is full of the core melt, undergoing natural circulation. These experiments are part of the EC-FOREVER Program in which vessel failure experiments have also been performed. The experiments are performed in a 1/10th scale vessel (400 mm diameter and 15 mm wall thickness) and the oxidic melt employed is the mixture CaO + B₂O₃ at 1400 K, representing the corium melt mixture of UO₂ + ZrO₂.The experiments employed an initial phase, during which uniform volumetric heating of the melt was provided and the vessel was pressurised to 25 bar, for several hours, to generate maximum creep deformation of 5%, in order to provide the conditions for the formation of a gap between the melt-pool crust and the bottom head wall. After this phase, the vessel was flooded with water.Data were obtained on only the vessel and the melt pool temperatures in one of the EC-FOREVER experiments reported here. In the second experiment, however, besides the temperature data, additional data were obtained on the steam flow rate and the heat transfer to the water, at the upper face of the melt pool, as a function of time.It was found that the gap cooling mechanism was not effective in reducing the vessel wall temperatures after water flooding. Post-test examinations revealed that the water ingression extended to the depth of only 60 mm in the melt pool. The character of the heat transfer to the water from the melt pool upper surface was found to be similar to that observed in the MACE tests for the coolability of an ex-vessel melt pool flooded by water at the top.     

Rapid Reversible Osmoregulation of Cytoplasmic Biomolecular Condensates of Human Interferon-α-Induced Antiviral MxA GTPase

We previously discovered that exogenously expressed GFP-tagged cytoplasmic human myxovirus resistance protein (MxA), a major antiviral effector of Type I and III interferons (IFNs) against several RNA- and DNA-containing viruses, existed in the cytoplasm in phase-separated membraneless biomolecular condensates of varying sizes and shapes with osmotically regulated disassembly and reassembly. In this study we investigated whether cytoplasmic IFN-α-induced endogenous human MxA structures were also biomolecular condensates, displayed hypotonic osmoregulation and the mechanisms involved. Both IFN-α-induced endogenous MxA and exogenously expressed GFP-MxA formed cytoplasmic condensates in A549 lung and Huh7 hepatoma cells which rapidly disassembled within 1–2 min when cells were exposed to 1,6-hexanediol or to hypotonic buffer (~40–50 mOsm). Both reassembled into new structures within 1–2 min of shifting cells to isotonic culture medium (~330 mOsm). Strikingly, MxA condensates in cells continuously exposed to culture medium of moderate hypotonicity (in the range one-fourth, one-third or one-half isotonicity; range 90–175 mOsm) first rapidly disassembled within 1–3 min, and then, in most cells, spontaneously reassembled 7–15 min later into new structures. This spontaneous reassembly was inhibited by 2-deoxyglucose (thus, was ATP-dependent) and by dynasore (thus, required membrane internalization). Indeed, condensate reassembly was preceded by crowding of the cytosolic space by large vacuole-like dilations (VLDs) derived from internalized plasma membrane. Remarkably, the antiviral activity of GFP-MxA against vesicular stomatitis virus survived hypoosmolar disassembly and subsequent reassembly. The data highlight the exquisite osmosensitivity of MxA condensates, and the preservation of antiviral activity in the face of hypotonic stress.     

Structural Dynamic Model Updating Techniques: A State of the Art Review

This paper presents a review of structural dynamic model updating techniques. Starting with a tutorial introduction of basic concepts of model updating, the paper reviews direct and iterative techniques of model updating along with their applications to real life systems. The main objective of this paper is to review the most widely applied model updating techniques so that beginners as well as practising engineers can appreciate, choose and then utilize the most suitable model updating technique for their customized application. Another objective is to highlight the current issues, applications and observations for further advancements in the field of model updating.     

Determinants of metabolic acidosis among hemodialysis patients

Metabolic acidosis is frequently present, poorly controlled, and associated with adverse effects among hemodialysis patients. Potential determinants of metabolic acidosis include endogenous acid production, administration of alkali, neutralization of acid by buffers, dilution of serum bicarbonate by interdialytic fluid gain, and loss of bicarbonate in stool. Understanding the relative importance of these determinants may help guide efforts to manage metabolic acidosis. We used chart abstraction, patient interviews, and laboratory testing to assess variables related to acid production (protein breakdown), alkali administration (dialysis dose, missed treatments, dialysate bicarbonate concentration, oral bicarbonate supplements), acid buffering (phosphorus binders), dilution of bicarbonate (interdialytic weight gain), and loss of bicarbonate in stool (diarrhea) for 190 randomly selected patients from 44 hemodialysis facilities. We used multivariate analyses to determine which potential determinants were independently associated with predialysis serum bicarbonate levels. Of all patients, 30% had metabolic acidosis (serum bicarbonate level <22 mEq/L). On multivariate analysis, metabolic acidosis was more likely with increased protein nitrogen appearance (odds ratio [OR] 1.60 per 0.2 g/kg/day, p=0.001) and less likely with increased Kt/V (OR 0.61 per 0.20 increase in Kt/V, p<0.001) and with increased calcium carbonate use (OR 0.38 per 2 g/day, p=0.003). Key determinants of metabolic acidosis among hemodialysis patients are protein breakdown, dialysis dose, and specific phosphorus binders. Further work is needed to develop interventions to address these determinants.     

Effect of iron (Wt.%) on adhesive wear response of Al-12Si-1Cu-0.1Mg alloy in dry sliding conditions

The presence of iron leads to different types of intermetallics in Al-Si alloys, among them needle shaped β-phase (Al₅FeSi) can lead to variations in hardness of the Al-Si alloy which ultimately can affect the wear resistance of the alloy. In this paper, the effect of iron on wear behavior of cast Al-Si alloys has been reported. Sliding wear behavior of eutectic alloy Al-12Si-1Cu-0.1Mg was investigated in dry sliding conditions by using pin-on-disk test configuration against heat treated EN31 steel counter-surface at room temperature. Sliding wear behavior has been evaluated at four normal loads of 5, 20, 50 and 70 N and two sliding speeds, 2 m/s and 4 m/s. Worn pin surfaces were examined by scanning electron microscopy (SEM) for analyzing wear mechanisms. The wear mechanism has been found to be mild oxidative type at lower sliding speed of 2m/s for entire range of loads used in the study. Transition to severe metallic wear occurs at higher sliding speed of 4 m/s at normal load of 5 N. Hardness of the alloy increased with increase in iron addition primarily due to presence of needle shaped Fe-rich intermetallics but it leads to an increased wear rate.     

G.V Black dental caries classification and preparation technique using optimal CNN-LSTM classifier

Multimedia Tools and Applications - Dental caries is one of the oral diseases which are a major health problem for many people across the globe. It can lead to pain, discomfort, disfigurement, and...     

Bake stability of CdTe and ZnS on HgCdTe: An x-ray photoelectron spectroscopy study

Mercury cadmium telluride (Hg_1?xCd_xTe or MCT) has been commonly used in devices for infrared (IR) detection. For the optimum performance of the device, a compatible surface-passivation technology that provides long-term stability is required. Using x-ray photoelectron spectroscopy (XPS), the present study examines the effects on Hg_0.8Cd_0.2Te passivated with CdTe and ZnS undergoing baking in vacuum at temperatures typically used for dewar bakeout. Spectra recorded as a function of depth in both cases clearly show out-diffusion of Hg from the substrate toward the surface, even before the bakeout. On baking in vacuum, dramatic changes are observed in the ZnS/MCT case with complete loss of Hg from the sample up to the tested depth of more than 1,000 Å. Compositions of the HgCdTe matrix, formed after Hg out-diffusion, before and after the bakeout are also calculated at selected depths (from 250 Å to 700 Å), which is vital information from a device point of view, as it affects the bandgap of this narrow-band semiconductor.     

Characterization of heat transfer processes in a melt pool convection and vessel-creep experiment

The results of an integral experiment on melt pool convection and vessel-creep deformation are presented and analyzed. The experiment is performed on a test facility, named Failure Of REactor VEssel Retention (FOREVER). The facility employs a 1/10-scaled 15Mo3-(German)-steel vessel of 400-mm diameter, 15-mm wall thickness and 750-mm height. A high-temperature (1300 °C) oxide melt is prepared in a SiC-crucible placed in a 50 kW induction furnace and is, then, poured into the 1/10th scale vessel. A MoSi₂ 50 kW electric heater is employed in the melt pool to heat and maintain its temperature at 1200 °C. The vessel is pressurized with argon at the desired pressure. In the FOREVER/C1 experiment, the vessel wall, maintained at about 900 °C and pressurized to 26 bars, was subjected to creep deformation in a 24-h non-stop test. The FOREVER/C1 test is the first integral experiment, in which a decay-heated oxidic naturally-convecting melt pool was maintained in long-term contact with the hemispherical lower head of a pressurized, creeping, steel vessel. A sizeable database was obtained on melt pool temperatures, melt pool energy split, heat transfer rates, heat flux distribution on the melt (crust)–vessel contact surface, vessel temperatures and, in particular the vessel wall creep rate as a function of time. The paper provides information on the FOREVER/C1 measured thermal characteristics and analysis of the observed thermal behavior. The coupled nature of thermal and mechanical processes, as well as the effect of other system conditions (such as depressurization) on the melt pool and vessel temperature responses are analyzed.