Das deutsche Arzneimittelpatent – eine moralische Bewertung

Definition of the problem

This paper deals with the question whether the current German intellectual property right on pharmaceuticals is morally justifiable. To answer this question, I will map the relevant discourse and arrange the different positions with respect to their level of abstraction.

Arguments

I underline that both deontological and consequentialist arguments point out the moral deficits within the system.

Conclusion

The consequentialist position emphasizes the unsatisfying relationship between patented pharmaceutical costs and the number of innovations on the market. The deontological approach on the other hand highlights the dangers to citizens’ autonomy.

     

Dystopie und Methode: zur fiktionalen Verhandlung moralischer Überzeugungen in der Bioethik

Definition of the problem

The role of stories is well established in the traditions of narrative ethics and casuistry. However, from a methodological point of view, the inclusion of fictional works in moral deliberation remains yet unanswered. The paper explains the potential of dystopias for bioethics by means of selected examples and a critical reconstruction and expansion of existing approaches.

Arguments

By means of literary theories, it is proposed to include moral beliefs that motivate dystopias in coherent reflection and reasoning procedures. Furthermore, dystopia’s potential through socioculturally dense scenarios, a contemporary-historical context, and a sensitization to the moral relevance of language for bioethical research are systematically presented.

Conclusion

The methodological considerations provide, on the one hand, practical points of reference for didactic approaches and, on the other hand, for public deliberation. However, the analysis also shows that dystopias introduce their own moral positions beyond a mere illustration or warning.

     

Spezifische Bedarfe bei zahnärztlichen Patienten mit Demenz und ihre ethischen Implikationen

Definition of the problem

The central foundations of successful dental treatment consist of a trustful patient-dentist relationship, the professional and psychosocial expertise of the team treating the patient, and consideration of ethical aspects both during the therapeutic decision-making process and during the subsequent execution of therapy. This is especially true of the dental treatment of (mostly elder) persons with dementia, calling for an in-depth assessment of the various normative implications.

Arguments

In geriatric dentistry in particular, situational dilemmas regarding treatment often arise from specific constellations (e.?g. greatly reduced potential for dental therapy, lack of ability regarding oral hygiene and lack of individual patient responsibility) combined with an acute need for treatment and the necessary involvement of third parties. These dilemmas frequently place additional professional and normative demands on the dentist. The current contribution discusses this specific situation, first by way of theoretical discourse and subsequently with a case-related approach on the basis of two case histories.

Conclusion

It becomes clear here that classic state-of-the-art therapies are replaced by “compromise treatment” in many cases in geriatric dentistry. Such treatment follows divergent diagnostic and therapeutic rules, poses changed requirements in terms of communication and presents specific ethical challenges and pitfalls.

     

Electrochemical behavior of magnolol on FeWO<Subscript>4</Subscript> nanoflower modified carbon paste electrode

In order to establish a simple, sensitive, and fast reliable detection method to determine the magnolol, FeWO₄ nanoflower was synthesised through a solvothermal technique and FeWO₄ nanoflower modified carbon paste electrode (CPE) was developed. The voltammetric behavior of magnolol on the modified electrodes was studied using cyclic voltammetry (CV), linear sweep voltammetry (LSV), and differential pulse voltammetry (DPV). The experimental results showed that the modified electrode remarkably enhanced the electrochemical response of the magnolol and exhibited a wide linear range for determination of the magnolol from 1.0×10^-7 to 1.0×10^-4 mol/L with a low detection limit of 5.0×10^-8 mol/L.