Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 modifications

The synthesis and antithrombotic activity of a series of nonpeptide bicyclic thrombin inhibitors is described. We have explored the SAR with modifications to the P1 site. The introduction of arginine mimetics at the P1 site led to potent and selective thrombin inhibitors.     

酞菁光敏剂对S180移植瘤的疗效

研究了GaS_4PC,ZnS_2PC两种酞菁在激光照射下对S180肉瘤的疗效,并讨论了其他酞菁光敏剂对癌细胞的杀伤效果。     

天津市正常人全血和血清微量元素含量分析

人体内微量元素含量平衡与否与人体健康状态有着密切关系已为大量实践所证实。人体血液中微量元素的正常值测定是研究人体健康与微量元素关系的一项基础性工作,本文提供了天津市正常人全血及血清中几种微量元素含量的数据。     

Nuclear proteins from liver and kidney bind a 37 bp sequence in the 5' upstream region of the mGAT1 gene

The mouse GABA transporter (mGAT1) gene has been shown to be exclusively expressed in brain by Northern and Western blot analyses. The interactions between the 5' flanking region of the mGAT1 gene and nuclear proteins from different mouse tissues were studied by means of gel-shift assay. Our results show that nuclear protein factors from non-nervous tissues can specifically recognize a 37 bp sequence that is conserved in the 5' flanking region between the human and mouse GAT1 genes. Similar nuclear protein factors were also found to exist in rat, rabbit and pig.     

复杂场景实时目标检测方法

针对含有非平稳背景的复杂场景,提出一种基于空间混合高斯模型的实时目标检测方法.该方法以混合高斯模型作为颜色分布的统计框架,并在空间邻域中利用背景与前景隶属度之间的竞争确定像素的归属,提高了检测准确率;同时通过基于偏差均值的匹配判断和低权重模型的移除提升了混合高斯统计框架的性能,以实时地对运动目标进行准确的检测.实验结果表明,文中方法对非平稳背景有很好的适应能力,在检测准确率和运行效率上均优于其他检测方法.     

RETRACTED ARTICLE: Design of traffic object recognition system based on machine learning

Neural Computing and Applications - In recent years, researchers have proposed many methods to solve the problem of obstacle detection. However, computer vision-based vehicle detection and...     

RETRACTED ARTICLE: Research on image classification method based on convolutional neural network

Neural Computing and Applications - Image classification method is currently the more popular image technology, but it still has certain problems in practice. In order to improve the image...     

基于FPGA和ARM的弹上相位自动微调控制器设计与实现

为了提高相位自动微调控制器的控制性能,针对某型导弹,提出并实现了以ARM+ FPGA双微处理器为核心的硬件设计方案,采用了模糊PID控制算法,通过优化步进电机控制模式,提高了相位自动微调控制器的控制精度,将步进电机的调整时间由800 ms缩短到100 ms以内;该方案已成功应用于某型弹上系统,实践证明,该设计方案成本低、可扩展性强,能够满足系统控制需求,具有较高的实用性,大大提高了装备维护效率.     

基于LabVIEW的虚拟车身CAN总线节点设计

为研究汽车车载CAN总线节点网络控制功能,通过对大众PASSAT1.8车身CAN总线系统的数据测试得该系统网络控制是以控制数据帧和状态数据帧的传输实现;选用通用CAN总线接口卡,上位机采用LabVIEW编程,设计虚拟左前门控单元节点模型样机;经实验表明,基于PC平台的虚拟车身CAN总线节点可替代实体车身CAN总线节点来实现原车网络控制功能,具有较强的开放性与灵活性,并可为车载CAN总线系统网络设计、测试与教学提供支撑.     

无线机电阻抗结构健康监测系统软件开发

机电阻抗技术是一种新兴的非参数结构健康监测方法,对结构局部微缺陷比较敏感;为了实现基于机电阻抗技术的结构健康监测,采用Visual C++和Matlab混合编程的方式设计和开发了系统监测软件;该软件用于控制现场的无线智能机电阻抗传感器进行数据采集,同时对测量数据进行处理,根据损伤评估算法评定结构健康状况;软件采用Visual C++编写系统人机交互界面和通信接口程序,采用Matlab编写数据处理和损伤评估算法,同时图形化输出运算结果;将两者的优势有机结合,从而缩短了软件的开发周期。