用EGS4分析9MeV行波直线加速器屏蔽系统

采用了国际上广泛使用的ＭｏｎｔｅＣａｒｌｏ模拟计算程序ＥＧＳ４对海关集装箱检测系统用加速器屏蔽系统进行了辐射模拟分析，与实际测试数据进行分析、比较，解释了特殊剂量分布的原因，提出了系统改进的参考方案。     

Mechanical stretch induces hypertrophic responses in cardiac myocytes of angiotensin II type 1a receptor knockout mice

Many lines of evidence have suggested that angiotensin II (AngII) plays an important role in the development of cardiac hypertrophy through AngII type 1 receptor (AT1). To determine whether AngII is indispensable for the development of mechanical stress-induced cardiac hypertrophy, we examined the activity of mitogen-activated protein kinase (MAPK) family and the expression of the c-fos gene as hypertrophic responses after stretching cultured cardiac myocytes of AT1a knockout (KO) mice. When cardiac myocytes were stretched by 20% for 10 min, extracellular signal-regulated protein kinases (ERKs) were strongly activated in KO cardiomyocytes as well as wild type (WT) myocytes. Both basal and stimulated levels of ERKs were higher in cardiomyocytes of KO mice than in those of WT mice. Activation of another member of the MAPK family, p38(MAPK), and expression of the c-fos gene were also induced by stretching cardiac myocytes of both types of mice. An AT1 antagonist attenuated stretch-induced activation of ERKs in WT cardiomyocytes but not in KO cardiomyocytes. Down-regulation of protein kinase C inhibited stretch-induced ERK activation in WT cardiomyocytes, whereas a broad spectrum tyrosine kinase inhibitor (genistein) and selective inhibitors of epidermal growth factor receptor (tyrphostin, AG1478, and B42) suppressed stretch-induced activation of ERKs in KO cardiac myocytes. Epidermal growth factor receptor was phosphorylated at tyrosine residues by stretching cardiac myocytes of KO mice. These results suggest that mechanical stretch could evoke hypertrophic responses in cardiac myocytes that lack the AT1 signaling pathway possibly through tyrosine kinase activation.     

程控交换机收号系统模拟的研究

本文提出了一种模拟程控交换机收号系统的有效方法,采用消息驱动收号事件表的思想,运用并发控制技术,实现了在没有话路硬设备的条件下多用户同时拨号在线模拟收号控制的功能。本文提出的收号系统模拟方案已成功应用于某国产中大容量程控交换机的呼叫模拟系统中。     

Genomic imprinting and carcinogenesis

The solution structure of a synthetic ET(B) selective agonist, ET-1[Cys(Acm)(1,15), Ala3, Leu7, dAsp8, Aib11] has been solved by 1H NMR and molecular modelling studies. Such solution structures of linear modified peptides in aqueous methanol are being used in an ongoing program of research designed to assist in an understanding of the basic structural requirements for the biological activity of vasoconstrictors. The resulting structure of this peptide is characterised by an alpha-helical conformation between residues Leu6-His16 and by N- and C-termini which assume no defined conformation. A knowledge of the solution structures of this and related peptides, which are ET(B) selective agonists, are proving to be important in the understanding of how they interact with the ET(B) receptor.     

从萨沃伊别墅探究勒·柯布西耶的机器美学

文章论述了萨沃伊别墅的机器美学思想,主要结合了勒·柯布西耶在1926年提出的"建筑新五点"来探讨他所主张的机器美学在萨沃伊别墅上是如何得以实现。     

无线ILC系统测控信号延时效应补偿方法

针对通过无线信道进行测控信号传输的远程迭代学习控制( ILC)系统,研究信号传输延时对控制系统性能的影响.分析了测控信号延时情况下ILC系统的收敛性问题,通过引入预控制向量,提出了ILC系统信道延时效应补偿的向量更新方法.数值仿真结果表明了所提方法的有效性.     

带曲率补偿的带隙基准电流源的设计

简单介绍了带隙基准源的基本原理,给出了一款基于Widlar结构的带曲率补偿的带隙基准电压电流源的设计方法,通过采用TSMC₀.5μm工艺库对电路进行仿真,在-40～150℃的温度范围内,其带隙基准的输出具有12ppm/℃的温度系数,电流基准的输出具有42ppm/℃。此外,文中还对曲率补偿电路的工作原理进行了分析,并且通过仿真波形对曲率补偿的工作机制进行了讨论。     

基于SSH的企业员工信息管理系统的设计与实现

以企业员工信息管理系统为例,论述该系统的设计及其实现,研究J2EE、Struts、Hibernate和Spring等主流技术在实际开发中的应用。结果表明,SSH技术架构在构建复杂业务系统中提高了开发效率和系统的可维护性,同时增强了系统的可扩展性。     

An online multiple object tracker based on structure keeper net

We propose a novel online multiple object tracker taking structure information into account. State-of-the-art multi-object tracking (MOT) approaches commonly focus on discriminative appearance features, while neglect in different levels structure information and the core of data association. Addressing this, we design a new tracker fully exploiting structure information and encoding such information into the cost function of the graph matching model. Firstly, a new measurement is proposed to compare the structure similarity of two graphs whose nodes are equal. With this measurement, we define a complete matching which performs association in high efficiency. Secondly, for incomplete matching scenarios, a structure keeper net (SKnet) is designed to adaptively establish the graph for matching. Finally, we conduct extensive experiments on benchmarks including MOT2015 and MOT17. The results demonstrate the competitiveness and practicability of our tracker.

     

Image classification method on class imbalance datasets using multi-scale CNN and two-stage transfer learning

Neural Computing and Applications - Image classification tasks widely exist in many actual scenarios, including medicine, security, manufacture and finance. A major problem that hurts algorithm...