山区拱桥缆索吊装施工模拟仿真设计分析

以宁德市寿宁县坪坑大桥拱桥缆索吊装施工过程监控为例,基于现场实测数据,利用桥梁分析软件Midas对施工过程监控进行仿真分析,重点探讨拱圈拱箱节段吊装合龙、桥面铺装完成及徐变10年后的计算分析结果,得出施工预拱度的合理建议值及正常使用极限状态的计算结论,成果将为保证拱桥成桥线形提供理论依据及更好地指导后续施工。     

Surgical repair of urethral circumcision injuries

PURPOSE: The 2 types of urethral injury that can occur during circumcision are urethrocutaneous fistula and urethral distortion secondary to partial glans amputation. We report the surgical repair of these rare injuries. MATERIALS AND METHODS: In 8 patients urethrocutaneous fistulas located on the distal penile shaft or at the coronal margin were managed by splitting the glans and using a Mathieu style skin flap in 4 or vascularized penile skin flap in 4 to bridge the urethral defect. Three patients underwent repair of a hypospadiac deviated urethra secondary to partial glans amputation by 1 cm. of urethral mobilization and repositioning the meatus into a terminal position within the remaining glans tissue. RESULTS: The 8 patients with urethrocutaneous fistulas voided via a terminal meatus without fistula recurrence at a mean followup of 3.2 years (range 1 to 6). The 3 patients with partial glans amputation and urethral deviation repaired by short urethral advancement had functionally acceptable results, defined as a normal urinary stream, although 1 required meatal dilation postoperatively. CONCLUSIONS: The 2 types of urethral injuries that can occur during circumcision are a subcoronal urethrocutaneous fistula and scarred abnormal urethra from partial glans amputation. The urethrocutaneous fistula can be successfully repaired by splitting the glans and forming a neourethra from a vascularized pedicle flap of penile skin. The abnormal urethra after partial glans amputation is more difficult to repair but repositioning the urethra in a more cosmetic location has restored function.     

Grape skin extract inhibits mammalian intestinal α-glucosidase activity and suppresses postprandial glycemic response in streptozocin-treated mice

Intestinal α-glucosidases are the key enzymes responsible for starch digestion and absorption and their inhibition has been proven effective in both preventing and treating diabetes through improvement of postprandial hyperglycaemia. This study, for the first time, identified that a Norton grape skin extract (GSE) significantly inhibited mammalian intestinal α-glucosidases but not other digestive enzymes including structurally relevant pancreatic α-amylase. Norton GSE inhibited rat intestinal α-glucosidases through a competitive mode with an IC₅₀ of 0.384 mg/ml. Further animal study revealed that the oral intake of Norton GSE (400 mg/kg) significantly reduced postprandial blood glucose by 30.9% in the streptozocin-treated male C57BL/6 J mice following starch challenge. These findings suggest that Norton GSE may have a unique property of suppressing postprandial blood glucose through a mechanism involving the inhibition of α-glucosidases, thereby providing a novel dietary opportunity for diabetes management.     

Mapping the thermal distribution within a silica preform tube using regenerated fibre Bragg gratings

The temperature profile of the reaction zone inside the silica substrate tube during thermal heating with a H₂/O₂ flame under conditions identical to those used in the fabrication of optical fibre preforms using a modified chemical vapour deposition lathe has been characterised with ultra-high temperature stable regenerated optical fibre Bragg gratings. Experimental and theoretical results indicate a significant drop in temperature – up to several hundred degrees – across the tube wall from outside to inside. These results are in contradiction with the broadly accepted assumption that there is no significant thermal gradient across the tube itself. An array of regenerated gratings demonstrates that optical fibre grating based sensing can achieve distributed ultra-high temperature mapping and monitoring in harsh environments.     

Using Multiple Solution Tasks for the Evaluation of Students’ Problem-Solving Performance in Geometry

Abstract

The article demonstrates that multiple solution tasks (MSTs) in the context of geometry can serve as a research instrument for evaluating geometry knowledge and creativity. Geometry knowledge is evaluated based on the correctness and connectedness of solutions, whereas creativity is evaluated based on a combination of fluency, flexibility, and originality of solutions. In this article, the MST research instrument is introduced in connection with the theoretical analysis of the research literature and then explained and analyzed using geometry students’ performance results on one MST. The analysis shows that the research instrument differentiates between students belonging to high- and regular-level instruction groups and sheds light on the interrelations between components of geometry knowledge and creativity.