Single nucleotide polymorphism data analysis - State-of-the-art review on this emerging field from a signal processing viewpoint

The basic structural units of the genome are nucleotides. A single nucleotide polymorphism (SNP) is a mutation at a single nucleotide position. This paper discusses several major problems in SNP data analysis and review some existing solutions in this work. Generally speaking, a rich set of SNP analysis problems are cast in the signal processing framework. Our objective is to offer a state-of-the art review on this topic from a signal processing viewpoint so that researchers in the signal processing field can grasp the important domain knowledge to overcome the barrier between the two fields     

纳米镍粉的制备工艺及产业化研究进展

综述了纳米镍粉的制备方法(包括物理法和化学法)及产业化现状,对纳米镍粉的各种制备方法进行了分析和评价。与物理法相比,化学法的产量高、成本低廉,能制备出性能优异的纳米镍粉,适合规模化生产;使用化学法制备的纳米镍粉的纯度、粒径及成本的控制仍需进一步加强。同时,对今后纳米镍粉的制备和产业化发展提出了建议。     

全球气候变暖对水资源的影响

全球气候变暖加剧了干旱、洪涝、台风等自然灾害的发生，是目前各国政府和社会公众普遍关注的热点问题。根据有关资料对气候变暖研究进展情况作相关介绍，可供参考。     

油田单井平均日产油量经济极限确定方法

从f(n,t)曲线的研究出发,得到了求解油田单井平均日产油量经济极限值的数学方程式,介绍了用曲线交汇法求解的过程,分析了油田月递减余率和原油销售价是影响油田单井平均日产油量经济极限的主要因素。该方法在油田开发调整方案的编制和油田开发规划部署工作中将起到一定的作用。     

纳米堵剂在油田超深疑难井封堵上的应用研究

封堵技术是油田“控水稳油”的主导技术之一,在油田开发中应用普遍。然而,近年国内新投入开发的油田中有相当数量的埋藏深、高温、高压、高矿化度、低渗透难开发的油藏,常规封堵剂适应性和安全性差,无法满足现场需求。因此研究开发了一种新型纳米堵剂,并对其性能进行了室内评价。室内评价结果表明,纳米堵剂浆体流变性和注入性能好,初凝时间可调,具有强度高、封堵率高、溶解率高、析水量少且体积不收缩、耐地下高温等特性。现场应用也表明,与油田常用高强度堵剂相比,具有耐高温、高压、高矿化度,强度高和易溶解的优势,且施工安全简便,措施成功率高,是解决超深疑难井堵水的一种新型封堵剂。     

润滑油资源与环境

解释了资源及环境的概念,讨论了润滑油资源与环境的关系,评述了润滑油如何适应环境保护的要求.     

Densitometry determination of dioxins using gold nanoparticlemodified dioxin response element probes

This study aims to develop a rapid and sensitive densitometry bioassay of dioxins. It is known that dioxin ligand can bind heterodimeric aryl hydrocarbon receptor (AhR) and trigger the formation of the complex of dioxin-AhR, AhR nuclear translocator (Arnt), and dioxin-responsive element (DRE). We have established a rapid and sensitive method using nanoparticle-modified DRE probes based on dioxin-dependent binding of DRE to AhR complex. Dioxins can trigger the binding of nanoparticle-modified DRE probe to AhR complex. The nanoparticle-modified DRE probes in the dioxin-AhR-Arnt-DRE complexes immobilized on the microplates were detected by measuring optical density after silver enhancement. Results showed that as little as 0.01 pM of TCDD could be detected. Dioxins could be quantified accurately with the linear range from 1 nM to 0.01 pM. The coefficient of variation was 5≈8% in this bioassay. The optical density of nanoparticle-based silver enhancement was produced in a dose- and time- dependent manner. The dioxin concentrations in fly ash samples determined by this bioassay were comparable with that by the standard HRGC/HRMS. Thus this bioassay is a sensitive and convenient cell-free bioassay of dioxin that is suitable for screening of dioxins in environmental or food matrices.     

New concept of surface modification to LiCoO2

As the continuance of our series study on LiCoO₂ surface modification, the complicated traditional surface coating method is replaced with simple addition of amorphous YPO₄ and Al₂O₃ in commercial LiCoO₂ or in commercial electrolyte based on our understanding to the improvement mechanism of surface modification. Comprehensive studies by X-ray photoelectron spectroscopy (XPS), gas chromatography and mass spectroscopy (GC–MS), inductively coupled plasma (ICP) and Fourier transformed infrared (FTIR) indicate that the products of spontaneous reaction between the additive and the LiPF₆ based electrolyte are responsible for the performance improvements.     

低压铸造流动与传热耦合计算的研究

根据低压铸造充型流动的特点 ,利用计算机数值模拟技术 ,对低压铸造充型阶段的流动怀传热过程进行了耦合计算 ,从而保证了模拟结果的准确性和可靠性。在此基础上开发出了模拟软件 ,并对实际低压铸件进行了模拟分析 ,结果与实际生产情况吻合很好     

NUMERICAL SIMULATION OF STRESS-INDUCED SECONDARY FLOWS WITH HYBRID FINITE ANALYTIC METHOD

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