Identification of Breast Cancer Prognosis Markers via Integrative Analysis

In breast cancer research, it is of great interest to identify genomic markers associated with prognosis. Multiple gene profiling studies have been conducted for such a purpose. Genomic markers identified from the analysis of single datasets often do not have satisfactory reproducibility. Among the multiple possible reasons, the most important one is the small sample sizes of individual studies. A cost-effective solution is to pool data from multiple comparable studies and conduct integrative analysis. In this study, we collect four breast cancer prognosis studies with gene expression measurements. We describe the relationship between prognosis and gene expressions using the accelerated failure time (AFT) models. We adopt a 2-norm group bridge penalization approach for marker identification. This integrative analysis approach can effectively identify markers with consistent effects across multiple datasets and naturally accommodate the heterogeneity among studies. Statistical and simulation studies demonstrate satisfactory performance of this approach. Breast cancer prognosis markers identified using this approach have sound biological implications and satisfactory prediction performance.     

Monitoring the Synthesis and Composition Analysis of Microsilica Encapsulated Acetylacetonatocarbonyl TriphenylphosphinerhodiumCatalyst by Inductively Coupled Plasma (ICP) Techniques

A novel technique to monitor the synthesis process of encapsulated acetylacetonatocarbonyl triphenylphosphinerhodium within a microsilica nanoshell has been studied using inductively coupled plasma (ICP) techniques. Nanospheres sized around 50-100 nm were obtained and ICP was used to quantify the exact composition of rhodium, phosphorous, and silicon with differing digestion solvents. In addition, ICP was used to detect rhodium and phosphorous in the nano core-shell catalysts as a quality control procedure     

基于Intel 815E芯片组的PCI-104 CPU模块设计

本文描述了基于Intel815E芯片组的PCl-104 CPU模块设计,对系统结构、总线拓扑、系统存储器以及外设等在设计过程中的注意事项作了阐述.     

喷射沉积柱坯的生长模型

根据现有喷射沉积设备的喷射几何关系推导了柱状沉积坯生长的数学模型,并利用该模型对沉积器的临界下降速度进行了初步估算。     

小波分析在三维地形数据简化中的应用研究

研究了小波分析在三维地形数据简化中的应用。在分析了小波多分辨率分析理论的基础上,重点探讨了小波多分辨率分析理论在三维地形简化中的应用,提出了实现三维地形数据简化的一种新的方法。     

A New Grade Carbon Black Produced by Thermal Plasma Process

This paper presents a new route about producing carbon black,by wich the natural gas cracking is carried out in the absence of oxygen thanks to an electric energy supply externally given by a plasma jet.The carbon black produced by this process has a narrow size distribution and a small average diameter of 38nm as well as a highly branched aggregate.The higher DBP value of 1.40ml/g shows it should be a high structure carbon black.The FTIR spectra shows that there are lots of aromatic c-c bonds and a large amount of nitrogen-coutaining functional groups on the carbon blacks surface,such as-NH,-CN as we3ll as -CH,-OH,-COOH groups.     

元数学对计算机科学的启示

文章提出了元数学对计算机科学的几点启示,这几个方面分别是传统程序设计的概念、机制、要素,数据库技术中的数据模型和函数依赖,面向对象分析和设计方法。文中一方面分析了元数学所提供的理论基础,另一方面说明了在应用方面是如何体现这些理论基础的,并提出了在计算机技术领域中应从数学基础问题、数理逻辑等的相关理论着手寻找突破的思想。     

A New ADI Scheme for Solving Three-Dimensional Parabolic Differential Equations

A new alternating-direction implicit (ADI) scheme for solving three-dimensional parabolic differential equations has been developed based on the idea of regularized difference scheme. It is unconditionally stable and second-order accurate. Further, it overcomes the drawback of the Douglas scheme and is to be very well to simulate fast transient phenomena and to efficiently capture steady state solutions of parabolic differential equations. Numerical example is illustrated.     

非正弦不对称三相三线电路负载侧相电压的定义与测量

对非正弦不对称三相三线电路，如何恰当地定义负载侧的相电压并能方便地测量一直未有明确的统一认识。本文从研究三相三线电路中相电压与线电压的关系着手，根据外部等效的思想。来定义三相三线电路负载侧的相电压。按此定义的相电压恒满足ｕ，＋“ｂ＋“ｃ＝０，并可方便地通过三相电压互感器或直接依据负载侧的线电压来唯一确定负载侧的相电压。     

触变泥浆润滑套在沉井工程中的应用

论述触变泥浆润滑套在沉井工程中的应用及主要参数。