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排序方式: 共有3866条查询结果,搜索用时 15 毫秒
91.
ME McCarty EA Grossi C Cutting CD Prevel R Elluru BL Eppley 《Canadian Metallurgical Quarterly》1995,16(7):476-481
In order to improve the understanding of the role of sympathetic nerve degeneration in reimplantation failure, the hindlimbs of eight rats (Group I) underwent near-complete amputation. The soft tissues of the hindlimb were transected at the proximal thigh with the femoral artery, vein and femur left intact. The femoral vessels were clamped and guanethidine was infused into a branch of the femoral artery of the right leg of each animal, while saline was injected into the left leg. The clamps were removed after 15 minutes. A baseline preoperative injection of radiolabeled microspheres was made, and subsequent injections at 6, 12, 18, and 24 hours postoperation. Twelve rats (Group II) were then used to assess the amount of arterial-venous shunting preoperatively (n = 6) and at 18 hours postoperation (n = 6), by venous sampling. Blood flow to both limbs increased postoperation, but there was significantly more flow in the guanethidine treated limb at 18 and 24 hours postoperation. The amount of shunting was approximately 50% in both limbs at 18 hours, as compared to 10% preoperation. These results highlight the potential benefit of guanethidine and other sympathetic blocking agents in reimplantation to increase blood flow, decrease tissue ischemia and increase anastomotic patency rates. They also suggest that sympathetic nerve degeneration did not affect the volume of arterial-venous shunting in this model, but the difference in blood flow was likely due to arteriolar vasospasm. Further study is needed to elucidate the clinical significance of sympathetic nerve degeneration in reimplantation failure. 相似文献
92.
ME D?schel 《Canadian Metallurgical Quarterly》1995,49(10):677-679
93.
ME Bertrand V Legrand J Boland E Fleck J Bonnier H Emmanuelson M Vrolix L Missault S Chierchia M Casaccia L Niccoli A Oto C White M Webb-Peploe E Van Belle EP McFadden 《Canadian Metallurgical Quarterly》1998,98(16):1597-1603
BACKGROUND: Dual therapy with ticlopidine and aspirin has been shown to be as effective as or more effective than conventional anticoagulation in patients with an optimal result after implantation of intracoronary metallic stents. However, the safety and efficacy of antiplatelet therapy alone in an unselected population has not been evaluated. METHODS: Patients were randomized to conventional anticoagulation or to treatment with antiplatelet therapy alone. Indications for stenting were classified as elective (decided before the procedure) or unplanned (to salvage failed angioplasty or to optimize the results of balloon angioplasty). After stenting, patients received aspirin and either ticlopidine or conventional anticoagulation (heparin or oral anticoagulant). The primary end point was the occurrence of bleeding or peripheral vascular complications; secondary end points were cardiac events (death, infarction, or stent occlusion) and duration of hospitalization. RESULTS: In 13 centers, 236 patients were randomized to anticoagulation and 249 to antiplatelet therapy. Stenting was elective in 58% of patients and unplanned in 42%. Stent implantation was successfully achieved in 99% of patients. A primary end point occurred in 33 patients (13.5%) in the antiplatelet group and 48 patients (21%) in the anticoagulation group (odds ratio=0.6 [95% CI 0.36 to 0.98], P=0.03). Major cardiac-related events in electively stented patients were less common (odds ratio=0.23 [95% CI 0.05 to 0.91], P=0.01) in the antiplatelet group (3 of 123, 2.4%) than the anticoagulation group (11 of 111, 9.9%). Hospital stay was significantly shorter in the antiplatelet group (4.3+/-3.6 versus 6. 4+/-3.7 days, P=0.0001). CONCLUSIONS: Antiplatelet therapy after coronary stenting significantly reduced rates of bleeding and subacute stent occlusion compared with conventional anticoagulation. 相似文献
94.
95.
ME Stefanek 《Canadian Metallurgical Quarterly》1995,7(6):527-530
Over the past year, increasing research attention has been devoted to the issue of women at increased risk of developing breast cancer. These articles focus on a range of issues from recruiting high-risk women into breast cancer trials to recommendations for assessment and counseling women with a family history of breast cancer. In addition, continuing research attention has focused on quality of life, symptom management, and articles related to physician-patient communication. This review summarizes and critiques publications in these areas, and it includes articles reviewing the status of research in psychosocial oncology. 相似文献
96.
D Sch?fer O Bianchi W Greulich C Sch?fer T Sch?fer ME Schl?fke 《Canadian Metallurgical Quarterly》1996,146(13-14):296-298
Most information about the structures within the brain stem that modulate respiration and sleep are gathered from animal experiments. Therefore we examined 10 patients several weeks after an infarction of the brain stem by means of polysomnography and tested the chemosensitive drives of respiration. None of these patients complained about symptoms of sleep disordered breathing. In each case polysomnographic measurements and ventilatory response curves revealed pathologic findings. The respiratory response to CO2 was diminished or completely abolished in each patient. In some cases hypoventilation or disturbances of the respiratory rhythmicity could be seen. In several cases missing REM sleep, sleep fragmentation or the reduction of slow wave sleep were observed. The study indicates that on the base of results from animal research the comparison of morphological and pathophysiological data is helpful to gain a better understanding on the coupling of the respiratory system with sleep at the brain stem level as well as on the pathomechanism of sleep related breathing disorder. 相似文献
97.
S. SIMARD M. DROGOWSKA H. ME´NARD L. BROSSARD 《Journal of Applied Electrochemistry》1997,27(3):317-324
The electrochemical behaviour of 1024 mild steel electrodes is investigated in the presence of 0.05–0.5 M sodium bicarbonate in aqueous solution at pH 8.9 and 25°C. Voltammograms are obtained with a rotating gold ring-mild steel electrode and the effect of the NaHCO3 concentration, the potential limits and the rotation speed of the disc electrode is considered. The voltammograms display an oxidation peak current at low potentials, a passivity region and a transpassive region at high potentials for the potential sweep in the anodic direction. The oxidation current in the passivity region is practically independent of the applied potential and the NaHCO3 concentration. The rate-determining step of the oxidation reaction in both the oxidation peak current region and the transpassive region is determined. 相似文献
98.
不稳定煤层采用单体液压支柱放顶煤开采技术,无疑是一种高效采煤方法。由于工作面采高大、单产高,且底层落煤与顶层放煤同时进行或工序间隔时间短,相应的采煤工作面瓦斯涌出量明显增大,采空区上部和工作面上方顶煤裂隙中易形成瓦斯积聚,从而严重威胁工作面的安全生产。本文通过分析简易放顶煤采煤工作面各生产工艺中瓦斯涌出规律,提出并实施有效的针对性综合瓦斯治理技术措施,实现了工作面的安全生产。 相似文献
99.
针对传统齿轮箱智能诊断系统获取知识的困难,提出了基于案例(case-based reasoning,CBR)和规则(rule-based reasoning,RBR)混合推理方式的智能诊断技术.在研究此2种推理技术优缺点的基础上,取长补短,合理地将其应用到轧机齿轮箱故障诊断工作中,提高了故障诊断的准确率和效率.针对传统案例检索中相似度算法的不足之处,提出了一种新的案例检索算法,有效地解决了传统的相似度算法检索案例不准确的问题. 相似文献
100.
研究和讨论了图像质量评估方法,提出一种基于模糊推理的块效应评估标准。假设图像由平滑区域、边缘区域以及纹理区域等组成,而且不同的区域应采用不同的方法进行质量评估。在此基础上,给出了三个分别适用于不同区域的图像质量评估因子,并提出了一个灵活的模糊图像质量评估方法。此方法把块效应和图像本身具有的边缘分开,防止了边缘会被误认为是块效应。仿真结果表明,提出的标准对于不同的图像具有鲁棒性,有一般图像质量评价标准的性能。 相似文献