VNS反应合成LLM-116

以1,3-二硝基吡唑为原料,经热重排、氨气中和得到3,5-二硝基吡唑铵盐,然后酸化得到3,5-二硝基吡唑。以三甲基肼碘化物（TMHI）作为异常亲核取代氢（VNS）反应试剂,与3,5-二硝基吡唑在叔丁醇钾为催化剂,利用VNS反应合成4-氨基-3,5-二硝基吡唑（LLM-116）。采用红外分析、核磁共振、元素分析等仪器鉴定了其结构,讨论了VNS反应机理及影响因素。通过实验,得出最佳VNS反应试剂为TMHI,反应时间为4h,反应温度为25℃,收率达到60%。     

全断面双护盾掘进机在引黄工程断层破碎带的卡机处理

万家寨引黄工程国际Ⅱ、Ⅲ标已查明的断层有34条，隐伏断层可能还有一些，除了利民堡区域性大断层（F32）外，较大的集中于7#洞北段59＋700—68＋820，主要有F65、F70、F90、F74。全断面双护盾掘进机适应于较复杂的地质条件，因此在通过断层破碎带时一般都较正常。但在通过引黄工程区域性大断层F65时，发生了卡机事故，处理用了3个月时间。该文对处理TBM卡机事故的施工进行了总结。     

基于Mega8单片机和AD9833的正弦波信号发生器

正弦波信号作为一种基准信号广泛应用于各种电路中，产生正弦波信号的方法有很多种，DDS（Direct Digital Frequency Synthesis直接数字频率舍成器）作为一种新型技术，具有相对带宽宽，频率转换时间短，频率分辨率高，控制灵活方便等优点，成为现代频率合成技术中的佼佼者。AD公司生产的AD9833是一款低功耗、可编程波形发生器，在Mega8单片机的控制下可生成0-12．5MHz的正弦波，还可以生成三角波和方波。经现场验证，基于Mega8单片机和AD9833的正弦波信号发生器，可以非常方便地生成各种频率的正弦波。     

词汇、语法和传情达意--一个湖边餐厅的习作

建筑设计往往是以传达情感为最终目的，因此语言的简单和熟练便显得愈发的重要。这个餐厅的设计尝试以简单的词汇组成直截的语言，力图清晰明确的传递建筑师的情感。     

科技写作手段电脑化的研究：计算机排版与科技期刊编辑

论述了计算机排版与科技期刊编辑的关系，以及编辑人员在计算机排版时应具备的能力，总结了计算机排版工作中积累的一些值得借鉴的经验。     

Reactive energy measurement using frequency controlled analog-to-pulse-rate converter

Contents This paper analyzes a problem of phase shifting and deseribes a novel method for electronic reactive energy measurement. The proposed measurement structure, composed of an integrator as a phase shifting circuit and a frequency controlled analog-to-pulse-rate converter, provides for the measurement completely in accordance with IEC definition of reactive energy, which is performed with simple but high performance metering device.

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Die Blindverbrauchsmessung anhand eines netzsynchronisierten Analog-Frequenz-Wandlers

Übersicht In diesem Artikel wird das Problem der Phasenverschiebung analysiert und eine neue Meßmethode für elektronische Blindverbrauschsmessung aufgezeigt. Die vorgeschlagene Strucktur, bestehend aus einem Integrator als Phasenschieber und netzkontrolliertem Analog-Frequenz-Wandler, ermöglicht die Verwirklichung eines einfachen aber präzisen Elektrizitätszählers zur Messung der Blindenergie, dessen Arbeitsprinzip mit den IEC Empfehlungen vollkommen übereinstimmt.

     

联合循环机组汽封系统的设计改进

介绍了联合循环汽轮机原汽封系统存在的问题以及改进后汽封系统的工作原理和运行控制过程。     

大花水水电站坝基地质条件及主要工程地质问题评价

大花水水电站碾压混凝土双曲拱坝最大坝高134.5 m,为目前国内外同类坝型坝高之最。大坝坝基处于软硬岩相间的顺向河谷上,大部分为强可溶岩地层,尤以沿垂直河向结构面及左岸古河床部位岩溶极发育。坝址左右岸地形不对称,地基岩性也软硬不均,工程地质条件极为复杂。大坝坝基存在的主要工程地质问题有坝基变形问题、抗滑稳定及渗漏问题等。工程开挖施工后,地质工程师对坝基基本地质条件进行了较详细的复核,并及时提出了适当的处理建议。     

Gas chromatography in express diagnosis of candidiasis and monitoring of antifungal therapy efficacy by D-arabinitol and mannose levels in pediatric patients]

Methods for preventing and treating Ebola virus hemorrhagic fever are not still available despite the fact that this virus have been studied for 20 years. Methods of immunization of the animals (sheep, goats) non-susceptible to Ebola virus with live virus preparations were developed to obtain the hyperimmune anti-Ebola virus sera required to have highly immune antivirus gamma-globulins. These methods made it possible to obtain the immune sera having high virus-neutralizing antibodies. Caprine immunoglobulins were obtained from sera by fractionation of immune sera by Kohn's method. The neutralization indices of the immunoglobulins obtained were at least Ig. When administered in the first hours of infection, the protective effect of these preparations was shown on guinea pigs infected with LD50 of the strain pathogenic to the animals. Preclinical trials of these immunoglobulins on laboratory animals and clinical trials on volunteers were performed. The preparation was used as a preventive agent when accidents took place at the laboratory working with Ebola virus. The similar preparation from equine sera having high neutralizing and protective properties was elaborated at the Virological Center, Microbiological Institute, Russian Ministry of Defense. Its prophylactic efficiency was also shown in infected gamadrias.     

A variational method for contour tracking via covariance matching

This paper presents a novel formulation for contour tracking.We model the second-order statistics of image regions and perform covariance matching under the variational level set framework.Specifically,covariance matrix is adopted as a visual object representation for partial differential equation(PDE) based contour tracking.Log-Euclidean calculus is used as a covariance distance metric instead of Euclidean distance which is unsuitable for measuring the similarities between covariance matrices,because the matrices typically lie on a non-Euclidean manifold.A novel image energy functional is formulated by minimizing the distance metric between the candidate object region and a given template,and maximizing the one between the background region and the template.The corresponding gradient flow is then derived according to a variational approach,enabling partial differential equations(PDEs) based contour tracking.Experiments on several challenging sequences prove the validity of the proposed method.